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172 items matching your search terms.
An essential role for the Zn(2+) transporter ZIP7 in B cell development
Anzilotti, C.; Swan, D. J.; Boisson, B.; Deobagkar-Lele, M.; Oliveira, C.; Chabosseau, P.; Engelhardt, K. R.; Xu, X.; Chen, R.; Alvarez, L.; Berlinguer-Palmini, R.; Bull, K. R.; Cawthorne, E.; Cribbs, A. P.; Crockford, T. L.; Dang, T. S.; Fearn, A.; Fenech, E. J.; de Jong, S. J.; Lagerholm, B. C.; Ma, C. S.; Sims, D.; van den Berg, B.; Xu, Y.; Cant, A. J.; Kleiner, G.; Leahy, T. R.; de la Morena, M. T.; Puck, J. M.; Shapiro, R. S.; van der Burg, M.; Chapman, J. R.; Christianson, J. C.; Davies, B.; McGrath, J. A.; Przyborski, S.; Santibanez Koref, M.; Tangye, S. G.; Werner, A.; Rutter, G. A.; Padilla-Parra, S.; Casanova, J. L.; Cornall, R. J.; Conley, M. E.; Hambleton, S.
NATURE IMMUNOLOGY 20 (3) :350-361, 2019 10.1038/s41590-018-0295-8
Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity
Edwards, E. S. J.; Bier, J.; Cole, T. S.; Wong, M.; Hsu, P.; Berglund, L. J.; Boztug, K.; Lau, A.; Gostick, E.; Price, D. A.; O'Sullivan, M.; Meyts, I.; Choo, S.; Gray, P.; Holland, S. M.; Deenick, E. K.; Uzel, G.; Tangye, S. G.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 143 (1) :276-291 e6, 2019 10.1016/j.jaci.2018.04.030
Mutations affecting the actin regulator WDR1 lead to aberrant lymphoid immunity
Pfajfer, L.; Mair, N. K.; Jimenez-Heredia, R.; Genel, F.; Gulez, N.; Ardeniz, O.; Hoeger, B.; Bal, S. K.; Madritsch, C.; Kalinichenko, A.; Chandra Ardy, R.; Gerceker, B.; Rey-Barroso, J.; Ijspeert, H.; Tangye, S. G.; Simonitsch-Klupp, I.; Huppa, J. B.; van der Burg, M.; Dupre, L.; Boztug, K.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 142 (5) :1589-1604, 2018 10.1016/j.jaci.2018.04.023
Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency
Kong, X. F.; Martinez-Barricarte, R.; Kennedy, J.; Mele, F.; Lazarov, T.; Deenick, E. K.; Ma, C. S.; Breton, G.; Lucero, K. B.; Langlais, D.; Bousfiha, A.; Aytekin, C.; Markle, J.; Trouillet, C.; Jabot-Hanin, F.; Arlehamn, C. S. L.; Rao, G.; Picard, C.; Lasseau, T.; Latorre, D.; Hambleton, S.; Deswarte, C.; Itan, Y.; Abarca, K.; Moraes-Vasconcelos, D.; Ailal, F.; Ikinciogullari, A.; Dogu, F.; Benhsaien, I.; Sette, A.; Abel, L.; Boisson-Dupuis, S.; Schroder, B.; Nussenzweig, M. C.; Liu, K.; Geissmann, F.; Tangye, S. G.; Gros, P.; Sallusto, F.; Bustamante, J.; Casanova, J. L.
NATURE IMMUNOLOGY 19 (9) :973-985, 2018 10.1038/s41590-018-0178-z
Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes
Moran, I.; Nguyen, A.; Khoo, W. H.; Butt, D.; Bourne, K.; Young, C.; Hermes, J. R.; Biro, M.; Gracie, G.; Ma, C. S.; Munier, C. M. L.; Luciani, F.; Zaunders, J.; Parker, A.; Kelleher, A. D.; Tangye, S. G.; Croucher, P. I.; Brink, R.; Read, M. N.; Phan, T. G.
Nature Communications 9 (1) :3372, 2018 10.1038/s41467-018-05772-7
Germline-activating mutations in PIK3CD compromise B cell development and function
Avery, D. T.; Kane, A.; Nguyen, T.; Lau, A.; Nguyen, A.; Lenthall, H.; Payne, K.; Shi, W.; Brigden, H.; French, E.; Bier, J.; Hermes, J. R.; Zahra, D.; Sewell, W. A.; Butt, D.; Elliott, M.; Boztug, K.; Meyts, I.; Choo, S.; Hsu, P.; Wong, M.; Berglund, L. J.; Gray, P.; O'Sullivan, M.; Cole, T.; Holland, S. M.; Ma, C. S.; Burkhart, C.; Corcoran, L. M.; Phan, T. G.; Brink, R.; Uzel, G.; Deenick, E. K.; Tangye, S. G.
JOURNAL OF EXPERIMENTAL MEDICINE 215 (8) :2073-2095, 2018 10.1084/jem.20180010
B cells race the clock to get a second wind
Phan, T. G.; Tangye, S. G.
NATURE IMMUNOLOGY 19 :791-793, 2018 10.1038/s41590-018-0166-3
A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity
Beziat, V.; Li, J.; Lin, J. X.; Ma, C. S.; Li, P.; Bousfiha, A.; Pellier, I.; Zoghi, S.; Baris, S.; Keles, S.; Gray, P.; Du, N.; Wang, Y.; Zerbib, Y.; Levy, R.; Leclercq, T.; About, F.; Lim, A. I.; Rao, G.; Payne, K.; Pelham, S. J.; Avery, D. T.; Deenick, E. K.; Pillay, B.; Chou, J.; Guery, R.; Belkadi, A.; Guerin, A.; Migaud, M.; Rattina, V.; Ailal, F.; Benhsaien, I.; Bouaziz, M.; Habib, T.; Chaussabel, D.; Marr, N.; El-Benna, J.; Grimbacher, B.; Wargon, O.; Bustamante, J.; Boisson, B.; Muller-Fleckenstein, I.; Fleckenstein, B.; Chandesris, M. O.; Titeux, M.; Fraitag, S.; Alyanakian, M. A.; Leruez-Ville, M.; Picard, C.; Meyts, I.; Di Santo, J. P.; Hovnanian, A.; Somer, A.; Ozen, A.; Rezaei, N.; Chatila, T. A.; Abel, L.; Leonard, W. J.; Tangye, S. G.; Puel, A.; Casanova, J. L.
Science Immunology 3 (24) 2018 10.1126/sciimmunol.aat4956
Combined Immunodeficiency with Ring Chromosome 21
Norman, M.; Wainstein, B.; Anazodo, A.; Turner, A.; Ma, C.; Payne, K.; Tangye, S. G.; Gray, P.
JOURNAL OF CLINICAL IMMUNOLOGY 38 (3) :251-256, 2018 10.1007/s10875-018-0493-z
Is it dead or alive? TLR8 can tell
Tangye, S. G.
NATURE IMMUNOLOGY 19 (4) :324-326, 2018 10.1038/s41590-018-0070-x
IRF4 haploinsufficiency in a family with Whipple's disease
Guerin, A.; Kerner, G.; Marr, N.; Markle, J. G.; Fenollar, F.; Wong, N.; Boughorbel, S.; Avery, D. T.; Ma, C. S.; Bougarn, S.; Bouaziz, M.; Beziat, V.; Della Mina, E.; Oleaga-Quintas, C.; Lazarovt, T.; Worley, L.; Nguyen, T.; Patin, E.; Deswarte, C.; Martinez-Barricarte, R.; Boucherit, S.; Ayral, X.; Edouard, S.; Boisson-Dupuis, S.; Rattina, V.; Bigio, B.; Vogt, G.; Geissmann, F.; Quintana-Murci, L.; Chaussabel, D.; Tangye, S. G.; Raoult, D.; Abel, L.; Bustamante, J.; Casanova, J. L.
eLife 7 (7) :e32340, 2018 10.7554/eLife.32340
Human plasma C3 is essential for the development of memory B, but not T, lymphocytes
Jimenez-Reinoso, A.; Marin, A. V.; Subias, M.; Lopez-Lera, A.; Roman-Ortiz, E.; Payne, K.; Ma, C. S.; Arbore, G.; Kolev, M.; Freeley, S. J.; Kemper, C.; Tangye, S. G.; Fernandez-Malave, E.; Rodriguez de Cordoba, S.; Lopez-Trascasa, M.; Regueiro, J. R.
JOURNAL OF CLINICAL IMMUNOLOGY 141 (3) :1153-1154, 2018 10.1016/j.jaci.2017.09.037
Reversible Suppression of Lymphoproliferation and Thrombocytopenia with Rapamycin in a Patient with Common Variable Immunodeficiency
Deenick, E. K.; Morey, A.; Danta, M.; Emmett, L.; Fay, K.; Gracie, G.; Ma, C. S.; Macintosh, R.; Smith, Sabc; Sasson, S. C.; Sewell, W. A.; Cowley, M.; Tangye, S. G.; Kelleher, A. D.; Circa; Phan, T. G.
JOURNAL OF CLINICAL IMMUNOLOGY 38 (2) :159-162, 2018 10.1007/s10875-018-0477-z
STAT3 regulates cytotoxicity of human CD57+ CD4+ T cells in blood and lymphoid follicles
Alshekaili, J.; Chand, R.; Lee, C. E.; Corley, S.; Kwong, K.; Papa, I.; Fulcher, D. A.; Randall, K. L.; Leiding, J. W.; Ma, C. S.; Wilkins, M. R.; Uzel, G.; Goodnow, C. C.; Vinuesa, C. G.; Tangye, S. G.; Cook, M. C.
Scientific Reports 8 (1) :3529, 2018 10.1038/s41598-018-21389-8
Circulating TFH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity
Koutsakos, M.; Wheatley, A. K.; Loh, L.; Clemens, E. B.; Sant, S.; Nussing, S.; Fox, A.; Chung, A. W.; Laurie, K. L.; Hurt, A. C.; Rockman, S.; Lappas, M.; Loudovaris, T.; Mannering, S. I.; Westall, G. P.; Elliot, M.; Tangye, S. G.; Wakim, L. M.; Kent, S. J.; Nguyen, T. H. O.; Kedzierska, K.
Science Translational Medicine 10 (428) 2018 10.1126/scitranslmed.aan8405
Circulating TFH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity
Koutsakos, M., Wheatley, A. K., Loh, L., Clemens, E. B., Sant, S., Nussing, S., Fox, A., Chung, A. W., Laurie, K. L., Hurt, A. C., Rockman, S., Lappas, M., Loudovaris, T., Mannering, S. I., Westall, G. P., Elliot, M., Tangye, S. G., Wakim, L. M., Kent, S. J., Nguyen, T. H. O., Kedzierska, K.
Science Translational Medicine 10 (428) :1-15, 2018 10.1126/scitranslmed.aan8405