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118 items matching your search terms.
OpenAccess publication BCL-2 hypermethylation is a potential biomarker of sensitivity to anti-mitotic chemotherapy in endocrine-resistant breast cancer.
Stone, A.; Cowley, M.J.; Valdes-Mora, F.; McCloy, R.; Sergio, C.M.; Gallego-Ortega, D.; Caldon, C. E.; Ormandy, C.J.; Biankin, A.V.; Gee, J. M.; Nicholson, R. I.; Print, C.G.; Clark, S.J.; and Musgrove, E.A.;
MOLECULAR CANCER THERAPEUTICS :Submitted, 2013
OpenAccess publication Epigenetic-induced repression of microRNA-205 is associated with MED1 activation and a poorer prognosis in localized prostate cancer
Hulf, T.; Sibbritt, T.; Wiklund, E.D.; Patterson, K.; Song, J.Z.; Stirzaker, C.; Qu, W.; Nair, S.; Horvath, L.G.; Armstrong, N.J.; Kench, J.G.; Sutherland, R.L.; Clark, S.J.
ONCOGENE 32 (23) :2891-9, 2013 10.1038/onc.2012.300
OpenAccess publication Regional activation of the cancer genome by long-range epigenetic remodeling
Bert, S.A.; Robinson, M.D.; Strbenac, D.; Statham, A.L.; Song, J.Z.; Hulf, T.; Sutherland, R.L.; Coolen, M.W.; Stirzaker, C.; Clark, S.J.
CANCER CELL 23 (1) :9-22, 2013 10.1016/j.ccr.2012.11.006
OpenAccess publication ELF5 supresses estrogen sensitivity and underpins the acquisition of anitestrogen resistance in luminal breast cancer.
Kalyuga, M.; Gallego-Ortega, D.; Lee, H. J.; Roden, D. L.; Cowley, M. J.; Caldon, C. E.; Stone, A.; Allerdice, S. L.; Valdes-Mora, F.; Launchbury, R.; Statham, A. L.; Armstrong, N.; Alles, M. C.; Young, A.; Egger, A.; Au, W.; Piggin, C. L.; Evans, C. J.; Ledger, A.; Brummer, T.; Oakes, S. R.; Kaplan, W.; Gee, J. M.; Nicholson, R. I.; Sutherland, R. L.; Swarbrick, A.; Naylor, M. J.; Clark, S. J.; Carroll, J. S.; Ormandy, C. J.;
PLOS BIOL 10 (12) :e1001461, 2012 10.1371/journal.pbio.1001461
OpenAccess publication Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in adva
Wee, E.J.H.; Peters, K.; Nair, S.S.; Hulf, T.; Stein, S.; Wagner, S.; Bailey, P.; Lee, S.Y.; Qu, W.J.; Brewster, B.; French, J.D.; Dobrovic, A.; Francis, G.D.; Clark, S.J.; Brown, M.A.
ONCOGENE 31 (38) :4182-95, 2012 10.1038/onc.2011.584
OpenAccess publication Copy-number-aware differential analysis of quantitative DNA sequencing data
Robinson, M. D.; Strbenac, D.; Stirzaker, C.; Statham, A. L.; Song, J. Z.; Speed, T. P.; Clark, S. J.;
GENOME RESEARCH 22 (12) :2489-96, 2012 10.1101/gr.139055.112
OpenAccess publication Integrative genome-wide expression and promoter DNA methylation profiling identifies a novel panel of ovarian cancer epigenetic biomarkers.
Gloss, B.S.; Patterson, K.I.; Barton, C.A.; Gonzalez, M.; Scurry, J.P.; Hacker, N.F.; Sutherland, R.L.; O'Brien, P.M.; Clark, S.J.;
CANCER LETTERS 318 :76-85, 2012 10.1016/j.canlet.2011.12.003
OpenAccess publication Bisulfite sequencing of chromatin immunoprecipitated DNA (BisChIP-seq) directly informs methylation status of histone-modified DNA
Statham, A.L.; Robinson, M.D.; Song, J.Z.; Coolen, M.W.; Stirzaker, C.; Clark, S.J.
GENOME RESEARCH 22 (6) :1120-7, 2012 10.1101/gr.132076.111
OpenAccess publication Prognostic and diagnostic significance of DNA methylation patterns in high grade serous ovarian cancer
Montavon, C.; Gloss, B. S.; Warton, K.; Barton, C. A.; Statham, A. L.; Scurry, J. P.; Tabor, B.; Nguyen, T. V.; Qu, W.; Samimi, G.; Hacker, N. F.; Sutherland, R. L.; Clark, S. J.; O'Brien, P. M.
GYNECOLOGIC ONCOLOGY 124 (3) :582-8, 2012 10.1016/j.ygyno.2011.11.026
OpenAccess publication Acetylation of H2A.Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer
Valdes-Mora, F.; Song, J.Z.; Statham, A.L.; Strbenac, D.; Robinson, M.D.; Nair, S.S.; Patterson, K.I.; Tremethick, D.J.; Stirzaker, C.; Clark, S.J.
GENOME RESEARCH 22 (2) :307-21, 2012 10.1101/gr.118919.110
OpenAccess publication Epigenome remodelling in breast cancer: insights from an early in vitro model of carcinogenesis
Locke, W. J.; Clark, S. J.;
BREAST CANCER RES 14 (6) :215, 2012
OpenAccess publication Androgen receptor expression predicts breast cancer survival: the role of genetic and epigenetic events.
Peters, K.M.; Edwards, S.L.; Nair, S.S.; French, J.D.; Bailey, P.J.; Salkield, K.; Stein, S.; Wagner, S.; Francis, G.D.; Clark, S.J.; Brown, M.A.;
BMC Cancer 12 :132, 2012 10.1186/1471-2407-12-132
OpenAccess publication MicroRNA alterations and associated aberrant DNA methylation patterns across multiple sample types in oral squamous cell carcinoma
Wiklund, E. D.; Gao, S.; Hulf, T.; Sibbritt, T.; Nair, S.; Costea, D. E.; Villadsen, S. B.; Bakholdt, V.; Bramsen, J. B.; Sorensen, J. A.; Krogdahl, A.; Clark, S. J.; Kjems, J.
PLoS One 6 (11) :e27840, 2011
OpenAccess publication DNA methylation: bisulphite modification and analysis
Patterson, K.; Molloy, L.; Qu, W.; Clark, S.
Jove-Journal of Visualized Experiments (56) :e3170, 2011 3170 [pii] 10.3791/3170
OpenAccess publication Impact of the genome on the epigenome is manifested in DNA methylation patterns of imprinted regions in monozygotic and dizygotic twins.
Coolen, M.W.; Statham, A.L.; Qu, W.; Campbell, M.J.; Henders, A.K.; Montgomery, G.W.; Martin, N.G.; Clark, S.J.
PLoS One 6 (10) :e25590, 2011 10.1371/journal.pone.0025590 PONE-D-11-10374 [pii]
OpenAccess publication miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA
Hansen, T. B.; Wiklund, E. D.; Bramsen, J. B.; Villadsen, S. B.; Statham, A. L.; Clark, S. J.; Kjems, J.;
EMBO JOURNAL 30 (21) :4414-22, 2011