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118 items matching your search terms.
OpenAccess publication Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodeling and mimics nucleosome positioning.
Hinshelwood, R.A.; Melki, J.R.; Huschtscha, L.I.; Paul, C.; Song, J.Z.; Stirzaker, C.; Reddel, R.R.; Clark, S.J.
HUMAN MOLECULAR GENETICS 18 (16) :3098-3109, 2009 10.1093/hmg/ddp251
OpenAccess publication Low 06-methylguanine-DNA methyltransferase (MGMT) expression and response to temozolomide in aggressive pituitary tumours
McCormack, A.I.; McDonald, K.L.; Gill, A.J.; Clark, S.J.; Burt, M.G.; Campbell, K.A.; Braund, W.J.; Little, N.S.; Cook, R.J.; Grossman A.B.; Robinson, B.G.; Clifton-Bligh, R.J.
CLINICAL ENDOCRINOLOGY 71 (2) :226-233, 2009 10.1111/j.1365-2265.2008.03487.x
OpenAccess publication Long range epigenetic silencing in 2q14.2 affects most human colorectal cancers and may have application as a non-invasive biomarker of disease
Mayor, R.; Casadome, L.; Azuara, D.; Moreno, V.; Clark, S.J.; Capella, G.; Peinado, M.A.
British Journal of Cancer 100 (10) :1534-1539, 2009 10.1038/sj.bjc.6605045
OpenAccess publication Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice
Guerrero-Bosagna, C. M.; Sabat, P.; Valdovinos, F. S.; Valladares, L. E.; Clark, S. J.
BMC Physiology 8 :17, 2008
OpenAccess publication Breast cancer epigenetics: normal human mammary epithelial cells as a model system
Hinshelwood, R.A.; Clark, S.J.
OpenAccess publication DNA methylation changes in ovarian cancer: implications for early diagnosis, prognosis and treatment
Barton, C. A.;Hacker, N. F.;Clark, S. J.;O'Brien, P. M. :
GYNECOLOGIC ONCOLOGY 109 (1) :129-39, 2008
OpenAccess publication Epigenetic markers of ovarian cancer
Barton, C. A.;Clark, S. J.;Hacker, N. F.;O'Brien, P. M. :
Advances in Experimental Medicine and Biology 622 :35-51, 2008
OpenAccess publication Concordant epigenetic silencing of transforming growth factor-beta signaling pathway genes occurs early in breast carcinogenesis
Hinshelwood, R. A.;Huschtscha, L. I.;Melki, J.;Stirzaker, C.;Abdipranoto, A.;Vissel, B.;Ravasi, T.;Wells, C. A.;Hume, D. A.;Reddel, R. R.;Clark, S. J. :
CANCER RESEARCH 67 (24) :11517-27, 2007
OpenAccess publication DNA methylation: bisulphite modification and analysis.
Clark, S. J.;Statham, A.;Stirzaker, C.;Molloy, P. L.;Frommer, M. :
Nature Protocols 1 (5) :2353-2364, 2007
OpenAccess publication Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer
Hitchins, M. P.;Lin, V. A.;Buckle, A.;Cheong, K.;Halani, N.;Ku, S.;Kwok, C. T.;Packham, D.;Suter, C. M.;Meagher, A.;Stirzaker, C.;Clark, S.;Hawkins, N. J.;Ward, R. L. :
CANCER RESEARCH 67 (19) :9107-16, 2007
OpenAccess publication Action at a distance: epigenetic silencing of large chromosomal regions in carcinogenesis
Clark, S. J. :
HUMAN MOLECULAR GENETICS 16 Spec No 1 :R88-95, 2007
OpenAccess publication Genomic profiling of CpG methylation and allelic specificity using quantitative high-throughput mass spectrometry: critical evaluation and improvements
Coolen, M. W.;Statham, A. L.;Gardiner-Garden, M.;Clark, S. J. :
NUCLEIC ACIDS RESEARCH 35 (18) :e119, 2007
OpenAccess publication DNA methylation: bisulphite modification and analysis
Clark, S. J.;Statham, A.;Stirzaker, C.;Molloy, P. L.;Frommer, M. :
Nature Protocols 1 (5) :2353-64, 2006
OpenAccess publication Permissive transcriptional activity at the centromere through pockets of DNA hypomethylation
Wong, N. C.;Wong, L. H.;Quach, J. M.;Canham, P.;Craig, J. M.;Song, J. Z.;Clark, S. J.;Choo, K. H. :
PLOS GENET 2 (2) :e17, 2006
OpenAccess publication Bisulphite differential denaturation PCR for analysis of DNA methylation
Rand, K. N.;Mitchell, S. M.;Clark, S. J.;Molloy, P. L. :
Epigenetics 1 (2) :94-100, 2006
OpenAccess publication Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band
Frigola, J.;Song, J.;Stirzaker, C.;Hinshelwood, R. A.;Peinado, M. A.;Clark, S. J. :
NATURE GENETICS 38 (5) :540-9, 2006