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Search results for mouse

567 items matching your search terms.
  1. Galanin receptor-1 knockout mice exhibit spontaneous epilepsy, abnormal EEGs and altered inhibition in the hippocampus

    Galanin is a widely-distributed neuropeptide that acts as an endogenous anticonvulsant. We have recently generated a galanin receptor type 1 knockout mouse ...

    Located in Research / Publications Search
  2. Neuropeptide Y2 receptor protein is present in peptidergic and nonpeptidergic primary sensory neurons of the mouse

    The localization of the neuropeptide tyrosine (NPY) Y2 receptor (Y2R) protein was studied in mouse dorsal root ganglia (DRGs) and spinal cord, by using a ...

    Located in Research / Publications Search
  3. A missense mutation in the gene encoding the alpha 1 subunit of the inhibitory glycine receptor in the spasmodic mouse

    Hereditary hyperekplexia, an autosomal dominant neurologic disorder characterized by an exaggerated startle reflex and neonatal hypertonia, can be caused by ...

    Located in Research / Publications Search
  4. Mouse prolactin receptor gene: genomic organization reveals alternative promoter usage and generation of isoforms via alternative 3'-exon splicing

    In rodents, the prolactin receptor is expressed as multiple isoforms with identical extracellular and membrane-proximal region sequences but with different 3' ...

    Located in Research / Publications Search
  5. Mouse models of inflammatory bowel disease - insights into the mechanisms of inflammation-associated colorectal cancer.

    The association between chronic inflammation and cancer has been noted for at least a century but the exact molecular mechanisms of cancer initiation and ...

    Located in Research / Publications Search
  6. Galanin mediates the pathogenesis of cerulein-induced acute pancreatitis in the mouse.

    OBJECTIVES: Acute pancreatitis (AP) is characterized by pancreatic microcirculatory and secretory disturbances. As galanin can modulate pancreatic vascular ...

    Located in Research / Publications Search
  7. A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to beta-Cell Mitochondrial Dysfunction in Type 2 Diabetes

    Type 2 diabetes (T2D) is a complex metabolic disease associated with obesity, insulin resistance and hypoinsulinemia due to pancreatic beta-cell dysfunction. ...

    Located in Research / Publications Search
  8. Early epigenetic downregulation of WNK2 kinase during pancreatic ductal adenocarcinoma development

    Pancreatic ductal adenocarcinoma (PDAC) is usually incurable. Contrary to genetic mechanisms involved in PDAC pathogenesis, epigenetic alterations are ill ...

    Located in Research / Publications Search
  9. Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength.

    Osteoporosis is a common polygenic disease and global healthcare priority but its genetic basis remains largely unknown. We report a high-throughput ...

    Located in Research / Publications Search
  10. Fat aussie--a new Alstrom syndrome mouse showing a critical role for ALMS1 in obesity, diabetes, and spermatogenesis

    Mutations in the human ALMS1 gene are responsible for Alstrom syndrome, a disorder in which key metabolic and endocrinological features include childhood-onset ...

    Located in Research / Publications Search
« Previous 10 items Next 10 items » 1 2 3 4 5 6 7 8 ... 57

Latest news

Clinical trial to test potential new combination therapy for aggressive breast cancer

Clinical trial to test potential new combination therapy for aggressive breast cancer

21 June 2022
Refining the teaching tools by creating better scientific animations

Refining the teaching tools by creating better scientific animations

10 June 2022
Stem-cell models reveal glaucoma secrets

Stem-cell models reveal glaucoma secrets

09 June 2022
New funding boosts Garvan breast cancer research

New funding boosts Garvan breast cancer research

17 May 2022
More news

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We acknowledge the Gadigal and Gundangara peoples, the traditional custodians of the lands on which the Garvan Institute and the ABR are located. We pay respects to Elders, past, present and future, and recognise their continuing connection and contribution to this land.

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