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567 items matching your search terms.
  1. Preparation of an awake mouse for recording neural responses and injecting tracers

    It is well known that anesthesia alters neural response properties in various regions of the brain. In the auditory system, fundamental response properties of ...

    Located in Research / Publications Search
  2. Metabolomic analysis of insulin resistance across different mouse strains and diets

    Insulin resistance is a major risk factor for many diseases. However, its underlying mechanism remains unclear in part because it is triggered by a complex ...

    Located in Research / … / CIRCA / CIRCA publications
  3. Pharmacological reduction of NEFA restores the efficacy of incretin-based therapies through GLP-1 receptor signalling in the beta cell in mouse models of diabetes

    AIMS/HYPOTHESIS: Type 2 diabetes mellitus is associated with reduced incretin effects. Although previous studies have shown that hyperglycaemia contributes to ...

    Located in Research / Publications Search
  4. Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density

    The genetic landscape of diseases associated with changes in bone mineral density (BMD), such as osteoporosis, is only partially understood. Here, we explored ...

    Located in Research / … / CIRCA / CIRCA publications
  5. Do transmembrane domain neuregulin 1 mutant mice exhibit a reliable sensorimotor gating deficit?

    Evidence suggests that the heterozygous transmembrane domain mutant mouse model for the schizophrenia candidate gene neuregulin 1 (Nrg1 HET) exhibits a deficit ...

    Located in Research / Publications Search
  6. Projections from the ventral nucleus of the lateral lemniscus to the cochlea in the mouse

    Auditory efferents originate in the central auditory system and project to the cochlea. Although the specific anatomy of the olivocochlear (OC) efferents can ...

    Located in Research / … / CIRCA / CIRCA publications
  7. Rho kinase inhibition blocks pancreatic ductal adenocarinoma invasion and tumor growth

    The high mortality of pancreatic cancer demands that new therapeutic avenues be developed. The orally available small-molecule inhibitor AT13148 potently ...

    Located in Research / … / CIRCA / CIRCA publications
  8. Prostate hyperplasia in a transgenic mouse with prostate-specific expression of prolactin

    Prolactin (PRL) is one of several polypeptide factors known to exert trophic effects on the prostate. We have previously reported a dramatic prostate ...

    Located in Research / Publications Search
  9. Rho Kinase Inhibition by AT13148 Blocks Pancreatic Ductal Adenocarcinoma Invasion and Tumor Growth

    The high mortality of pancreatic cancer demands that new therapeutic avenues be developed. The orally available small-molecule inhibitor AT13148 potently ...

    Located in Research / … / CIRCA / CIRCA publications
  10. Behavioural characteristics of the Prader-Willi syndrome related biallelic Snord116 mouse model

    Prader-Willi syndrome (PWS) is the predominant genetic cause of obesity in humans and is associated with several behavioural phenotypes such as altered motoric ...

    Located in Research / Publications Search
« Previous 10 items Next 10 items » 1 ... 4 5 6 7 8 9 10 ... 57

Latest news

Clinical trial to test potential new combination therapy for aggressive breast cancer

Clinical trial to test potential new combination therapy for aggressive breast cancer

21 June 2022
Refining the teaching tools by creating better scientific animations

Refining the teaching tools by creating better scientific animations

10 June 2022
Stem-cell models reveal glaucoma secrets

Stem-cell models reveal glaucoma secrets

09 June 2022
New funding boosts Garvan breast cancer research

New funding boosts Garvan breast cancer research

17 May 2022
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We acknowledge the Gadigal and Gundangara peoples, the traditional custodians of the lands on which the Garvan Institute and the ABR are located. We pay respects to Elders, past, present and future, and recognise their continuing connection and contribution to this land.

Garvan is committed to ensuring equity, diversity, inclusion and belonging are in our DNA and we are proud of what we can achieve when our people can come together.

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The Garvan Institute of Medical Research (ABN 62 330 391 937) and the Garvan Research Foundation (ABN 91 042 722 738) are registered charities.

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