(missing name)
Biography
Radhika completed her PhD at the National Institute of Immunology in New Delhi, India, after being awarded two fellowships from the Department of Biotechnology (India) in 2003.
After a career break, she was awarded the prestigious international Career Development Fellowship from the Medical Research Council for her post- doctoral work at Hutchison / MRC Cancer Centre, Cambridge UK in 2005. She then relocated to Australia to work with Dr Alex Swarbrick at the Garvan Institute.
Radhika completed her PhD at the National Institute of Immunology in New Delhi, India, after being awarded two fellowships from the Department of Biotechnology (India) in 2003.
After a career break, she was awarded the prestigious international Career Development Fellowship from the Medical Research Council for her post- doctoral work at Hutchison / MRC Cancer Centre, Cambridge UK in 2005. She then relocated to Australia to work with Dr Alex Swarbrick at the Garvan Institute.
Awards and Honours
2000 - Senior Research Fellowship in 2000 for 3 years by DBT, Government of India
1998 - Junior Research Fellowship in 1998 for 2 years by DBT, Government of India
1997 - Bombay University merit based scholarship for MSc
Education
1998 - 1st class M.Sc., Biochemistry, Institute of Science, Bombay - India
1996 - 1st class Honours BSc, Microbiology Biochemistry, St. Xavier’s College, Bombay - India
Selected Publications
Pimentel B*, Nair R*,Bermejo-Rodriguez C, Agu C, Preston M, Wang X,Bernal JA, Sherrat D and de la Cueva-Mendez G. Toxin Kid uncouples DNA replication and cell division to enforce retention of plasmid R1 in E.coli cells . (* co first authors). Jan 21 2014; Proceedings of the National Academy of Sciences
Nair R*, Teo SW*, Mittal V, Swarbrick A. ID proteins regulate diverse aspects of cancer progression and provide novel therapeutic oppurtunities. (* co-first authors). May 2014 Molecular Therapy
Teo SW, Nair R, Swarbrick A. New insights into the role of ID proteins in breast cancer metastasis: a MET affair. May 2014 Breast Cancer Research
Nair R, Roden D, Teo WS, McFarland A, Junankar S , Ye S, Nguyen A, Yang J , Nikolic I, Morey A, Shah J, Selinger C, Baker LA, Cowley M, Naylor MJ, Ormandy CJ, Lakhani SR, Kaplan W, O’Toole SA, Swarbrick, A. A Myc transcriptional program that is independent of EMT drives a poor prognosis tumour- propagating phenotype in HER2+ breast cancer. Sep 23 2013, Oncogene.
Karlo Dante T. Natividad; Simon Rajesh Junankar; Norhanani Mohd Redzwan; Radhika Nair; Rushika Christina Wirasinha; Cecile King; Robert Brink; Alexander Swarbrick; Marcel Batten. Interleukin-27 signaling promotes immunity against endogenously arising murine tumors. Plos One 2013; 8(3):e57469.
Mun Hui, Aurélie Cazet, Radhika Nair, D Neil Watkins, Sandra A. O’Toole and Alexander Swarbrick. The Hedgehog Signalling Pathway in Breast Development, Carcinogenesis and Cancer Therapy. Review. Breast Cancer Research. 2013; 15(2):203
O’Toole, S.A., Machalek, D., Shearer, R., Millar, E.A., Nair, R., McLeod, D., Cooper, C., McFarland, A., Qiu, M., McNeil, C.M., Rabinovich, B., Martelotto, L., Vu, D., Sutherland, R.L., Watkins, N., and Swarbrick, A. Hedgehog ligand overexpression predicts poor outcome and is a potential therapeutic target for metastatic disease. Cancer Research. 2011; 71(11):4002-4014.
Hochgräfe, F., Zhang, L., O’Toole, S., Browne, B.C., Pinese, M., Porta Cubas, A., Lehrbach, G.M., Croucher, D.R., Rickwood, D., Boulghourjian, A., Shearer, R., Nair, R., Swarbrick, A., Biankin, A.V., Sutherland, R.L., J., R.M., and Daly, R.J. Tyrosine phosphorylation profiling reveals the signaling network characteristics of basal breast cancer cells. Cancer Research. 2010; 70(22):9391-401.
Nair, R., Junankar, S., O'Toole, S., Shah, J., Borowsky, A.D., Bishop, J.M., and Swarbrick, A. Redefining the expression and function of the inhibitor of differentiation 1 in mammary gland development. PLoS ONE. 2010;5: e11947.
Nair R, Shaha C. Diethylstilbestrol induces rat spermatogenic cell apoptosis in vivo through increased expression of spermatogenic cell Fas/FasL system. J. Biol. Chem. 2003; 278(8): 6470-6481.