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Dr Thach Tran

After completing his doctor of medicine and specialist training in Obstetrics Gynaecology (OG), Dr. Tran completed his PhD on clinical epidemiology of nosocomial infection in OG at Prince of Songkla University in 1999. He previously worked as both a senior consultant in OG and a university lecturer

Research Level

Research Officer

Biography

After completing his doctor of medicine and specialist training in Obstetrics & Gynaecology (OG), Dr. Tran completed his PhD on clinical epidemiology of nosocomial infection in OG at Prince of Songkla University in 1999. He previously worked as both a senior consultant in OG and a university lecturer in Vietnam until 2011 when he migrated to Australia. He was also working as a technical consultant and member of World Health Organisation (WHO) guideline development groups in management of high risk pregnancy (2006-2014), and a primary statistician for several large randomized controlled trials in Australia (2011-2014). He has extensive experience in experimental design and data analysis, including modelling complex longitudinal related data, developing a prediction model, and analyzing linked health care data, as well as managing big and complex datasets, particularly nation-wide linked data. 

Since 2014, Dr Tran has been playing an important role in the analysis of observational data from several large prospective cohorts to determine the contribution of fragility fractures on mortality and develop a model for predicting the conceptual risks of both fragility fractures and mortality in the elderly. He is interested in the implementation of novel and robust statistical analysis approaches to investigate the trajectories to subsequent hospital admissions and mortality following specific fragility fractures, and the interactions between multimorbidity and post-fracture mortality.

After completing his doctor of medicine and specialist training in Obstetrics & Gynaecology (OG), Dr. Tran completed his PhD on clinical epidemiology of nosocomial infection in OG at Prince of Songkla University in 1999. He previously worked as both a senior consultant in OG and a university lecturer in Vietnam until 2011 when he migrated to Australia. He was also working as a technical consultant and member of World Health Organisation (WHO) guideline development groups in management of high risk pregnancy (2006-2014), and a primary statistician for several large randomized controlled trials in Australia (2011-2014). He has extensive experience in experimental design and data analysis, including modelling complex longitudinal related data, developing a prediction model, and analyzing linked health care data, as well as managing big and complex datasets, particularly nation-wide linked data. 

Since 2014, Dr Tran has been playing an important role in the analysis of observational data from several large prospective cohorts to determine the contribution of fragility fractures on mortality and develop a model for predicting the conceptual risks of both fragility fractures and mortality in the elderly. He is interested in the implementation of novel and robust statistical analysis approaches to investigate the trajectories to subsequent hospital admissions and mortality following specific fragility fractures, and the interactions between multimorbidity and post-fracture mortality.

Awards and Honours

- American Society of Bone and Mineral Research (ASBMR) Mid-Career Travel Grant (2017)
- MSD-Australia New Zealand Bone and Mineral Research (ANZBMS) Clinical Research Excellent Award (2016)
- International Federation of Gynecology and Obstetrics (FIGO) Fellowship (2006)
- International Federation of Gynecology and Obstetrics (FIGO) Fellowship (2000)
- Asian Oceanic Federation of Obstetricians and Gynecologists (AOFOG) Young Gynaecologist Award (2000)

Education

- MS in Biostatistics, University of Sydney, Australia (in progress)
- PhD in Clinical Epidemiology, 1999, Prince of Songkla University, Thailand
- Level-1 specialist in Obstetrics& Gynaecology, 1996, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam
- Medical Doctor, 1994, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam

Fundings

- Research Human Resource Development Grant of UNFPA/WHO/World Bank special program of research, development and research training in human reproduction (1996-1999) 

Selected Publications

  1. Tran T, Bliuc D, Pham MH, et al. A risk assessment tool for predicting fragility fractures and mortality in the elderly. [Accepted for publication in J Bone Miner Res. May 2020]
  2. Crowther CA, Ashwood P, Andersen CC, Middleton PF, Tran T, Doyle LW, Robinson JS, Harding JE; ASTEROID Study Group. Maternal intramuscular dexamethasone versus betamethasone before preterm birth (ASTEROID): a multicentre, double-blind, randomised controlled trial. Lancet Child Adolesc Health. 2019 Sep 12. pii: S2352-4642(19)30292-5. doi: 10.1016/S2352-4642(19)30292-5.
  3. Bliuc D, Tran T, van Geel T, et al. Reduced Bone Loss Is Associated With Reduced Mortality Risk in Subjects Exposed to Nitrogen Bisphosphonates: A Mediation Analysis. J Bone Miner Res. 2019 Aug 12. doi: 10.1002/jbmr.3816.
  4. Nguyen PTK, Tran HT, Tran TS, Fitzgerald DA, Graham SM, Marais BJ. Predictors of 'unlikely bacterial pneumonia' and 'adverse pneumonia outcome' in children admitted to hospital in central Vietnam. Clin Infect Dis. 2019 May 27. pii: ciz445. doi: 10.1093/cid/ciz445.
  5. Mai HT, Tran TS, Ho-Le TP, Center JR, Eisman JA, Nguyen TV. Two-thirds of all fractures are not attributable to osteoporosis and advancing age: implication for fracture prevention. J Clin Endocrinol Metab. 2019 Apr 5. pii: jc.2018-02614. doi: 10.1210/jc.2018-02614.
  6. Bliuc D, Tran T, van Geel T, et al. Mortality risk reduction differs according to bisphosphonate class: a 15-year observational study. Osteoporos Int. 2019 Jan 3. doi: 10.1007/s00198-018-4806-0.
  7. Mai HT, Tran TS, Ho-Le TP, Pham TT, Center JR, Eisman JA, Nguyen TV. Low-trauma rib fracture in the elderly: Risk factors and mortality consequence. Bone. 2018 Nov;116:295-300.
  8. Tran T, Bliuc D, Hansen L, et al. Persistence of excess mortality following individual non-hip fractures: A relative survival analysis. J Clin Endocrinol Metab. 2018 Sep 1;103(9):3205-3214.
  9. van Geel TACM, Bliuc D, Geusens PPM, Center JR, Dinant GJ, Tran T, van den Bergh JPW, McLellan AR, Eisman JA. Reduced mortality and subsequent fracture risk associated with oral bisphosphonate recommendation in a fracture liaison service setting: A prospective cohort study. PLoS One. 2018 Jun 1;13(6):e0198006. doi: 10.1371/journal.pone.0198006. eCollection 2018.
  10. Chen W, Simpson JM, March LM, Blyth FM, Bliuc D, Tran T, Nguyen TV, Eisman JA, Center JR. Co-morbidities only account for a small proportion of excess mortality after fracture: a record linkage study of individual fracture types. J Bone Miner Res. 2018 Jan 4.
  11. Crowther CA, Ashwood P, McPhee AJ, Flenady V, Tran T, Dodd JM, Robinson JS; PROGRESS Study Group. Vaginal progesterone pessaries for pregnant women with a previous preterm birth to prevent neonatal respiratory distress syndrome (the PROGRESS Study): A multicentre, randomised, placebo-controlled trial. PLoS Med. 2017 Sep 26;14(9):e1002390.
  12. Tran T, Bliuc D, van Geel T, et al. Population-Wide Impact of Non-Hip Non-Vertebral Fractures on Mortality. J Bone Miner Res. 2017 Sep;32(9):1802-1810.
  13. Tran TS, Center JR, Seibel MJ, Eisman JA, Kushnir MM, Rockwood AL, Nguyen TV. Relationship between Serum Testosterone and Fracture Risk in Men: A Comparison of RIA and LC-MS/MS. Clin Chem. 2015 Sep;61(9):1182-90.
  14. Tran TS, Hirst JE, Do MAT, Morris JM, Jeffery HE. Early prediction of gestational diabetes in Vietnam: Clinical impact of currently recommended diagnostic guidelines. Diabetes Care. 2013;36(3):618-24.
  15. Hirst JE, Tran TS, Do MAT, Morris JM, Jeffery HE. Consequences of Gestational Diabetes in an Urban hospital in Vietnam: A Prospective Cohort Study. PLos Medicine 2012;9:e1001272. doi:10.1371/journal.pmed.1001272
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