Program
PROGRAM - Australian Polygenic Risk Symposium, 2019
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Monday 18 November 2019 |
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| 12.00pm | Arrival, Registration, Lunch | |
| 12.45pm | Welcome | Professor Chris Goodnow |
| Session 1: International perspectives | ||
| Chair: Mary-Anne Young | ||
| 1.00 pm | From GWAS to personalized risk prediction: the experience from the Estonian Biobank and some methodological challenges |
Professor Krista Fischer Estonian Genome Center, Institute of Genomics, University of Tartu, Estonia |
| Perspectives on PRS |
Dr Tamsin Eades Illumina, Inc. |
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| Theory of polygenic risk |
Professor Naomi Wray Institute for Molecular Bioscience and Queensland Brain Institute, The University of Queensland |
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| 3.30pm |
Session 2: Theory to practice in Australia |
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| Chair: Georgia Chenevix-Trench |
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| Practical and clinical: the how to of PRS |
Associate Professor Paul James Parkville Familial Cancer Centre (Royal Melbourne Hospital and Peter MacCallum Cancer Centre) |
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| Polygenic risk scores and clinical utility in cardiovascular disease |
Associate Professor Mike Inouye The Baker Heart and Diabetes Institute and the University of Cambridge |
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| Polygenic risk in migraine and comorbid disorders |
Professor Dale Nyholt Queensland University of Technology |
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| **Accepted abstract: Improved polygenic risk score accuracy for 50 traits in biobank scale data by exploiting phenotypes on inferred relatives |
Associate Professor S. Hong Lee University of South Australia
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| 6-9pm | Social function | |
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Tuesday 19 November 2019
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| 9.00am | Welcome |
Associate Professor Sarah Kummerfeld Mary-Anne Young Kinghorn Centre for Clinical Genomics |
| Session 3: Polygenic risk and common complex disorders |
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| Chair: Naomi Wray |
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| International plenary: Polygenic risk scores in psychiatric disorders across disease course |
Professor Cathryn Lewis King's College London |
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| **Accepted abstract: Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke |
Dr Gad Abraham Baker Heart and DIabetes Institute; University of Cambridge; University of Melbourne |
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| **Accepted abstract: Predicting the future of predicting the future |
Associate Professor Stuart Macgregor QIMR Berghofer Medical Research Institute |
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| 11.00am | Session 4: Accepted abstracts in polygenic risk |
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| Chair: Lyn Griffiths |
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| Accepted abstract: Polygenic risk scores and breast and epithelial ovarian cancer risks for BRCA1 and BRCA2 carriers |
Professor Georgia Chenevix-Trench QIMR Berghofer Medical Research Institute |
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| **Accepted abstract: Testing rare disease polygenic risk with trios |
Dr Mark Pinese Children's Cancer Institute |
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| **Accepted abstract: Genomic Risk Scores for Predicting Juvenile Idiopathic Arthritis |
Dr Rodrigo Canovas Cambridge Baker Systems Genomics Initiative, The Baker Heart and Diabetes Institute |
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| **Accepted abstract: Polygenic risk and monogenic risk in glaucoma |
Dr Owen Siggs Flinders University |
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| **Accepted abstract: Clinical phenotype of glaucoma patients stratified by an intraocular pressure polygenic risk score |
Dr Ayub Qassim Flinders University |
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| **Accepted abstract: Pharmacological enrichment of polygenic risk for precision medicine in complex disorders |
William Reay School of Biomedical Sciences and Pharmacy, The University of Newcastle and Centre for Brain and Mental Health Research, Hunter Medical Research Institute |
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| 1.15pm | Session 5: Implementation | |
| Chair: Anne Cust | ||
| Implementing a polygenic risk score to tailor colorectal cancer screening in primary care |
Professor Jon Emery The University of Melbourne and the Victorian Comprehensive Cancer Centre |
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| PRS and implementation in melanoma |
Associate Professor Anne Cust Melanoma Institute Australia and The University of Sydney School of Public Health |
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Strategies for the implementation of polygenic risk models |
Dr Richard Allman Genetic Technologies Ltd and University of Melbourne |
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Risk-stratified population cancer screening: Is it acceptable to the general public and GPs? |
Kate Dunlop The University of Sydney School of Public Health |
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| **Accepted abstract: New Zealand Health Practitioner’s Perspectives Towards the Utility and Implementation of Polygenic Risk Scores |
Brittany Jones University of Otago, Department of Mathematics and Statistics |
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| 3.40pm | Session 6: Challenges to implementation |
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Chair: Jon Emery |
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Polygenic risk scores: challenges with implementation and workforce training needs
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Tatiane Yanes Postdoctorate Research Fellow, The University of Queensland Diamantina Institute |
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Insurance and polygenic risk |
Nick Kirwan Financial Services Council |
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Panel: in which disease contexts would we expect to see utility in PRS soonest? Moderator: Mary-Anne Young Panellists: A/Prof Anne Cust, Prof Jon Emery, Prof Dave Evans, Prof Krista Fischer, A/Prof Michael Inouye, Prof Cathryn Lewis, A/Prof Paul James |
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5.30pm |
Close |
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**Accepted abstracts are available in the APRS19 Accepted Abstracts Booklet
