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17 Jun 2019

How does cellular genomics work?

We have trillions of cells in our body – a single, individual cell can impact health and disease.

Cellular genomics is a revolutionary technology that’s transforming biological and medical research. 

Where whole genome sequencing is the study of all our DNA averaged over millions of cells, cellular genomics is the study of the genetic makeup of a single cell – from the cell’s entire DNA code (its genome), to the secondary code that organises the genome (its epigenome), and the total genetic output of the cell (its transcriptome). 

Cutting-edge cellular genomics technologies make it possible to unlock unprecedented insights into how cells work individually, and how they function together, in ways that were impossible only a few years ago. The Garvan-Weizmann Centre for Cellular Genomics, led by Associate Professor Joseph Powell, is one of the few global sites where state-of-the-art technologies are seamlessly integrated, including the latest platforms in flow cytometry, microfluidics, genomics, high-performance computing and bioinformatics.