Dr Kate Patterson

Senior Visual Science Communications Officer

Dr Kate Patterson

I am a visual science communicator and create 3D molecular animations and immersive visualisation experiences to engage broad audiences more deeply in the important research endeavours at Garvan. I practiced as a veterinarian before coming to Garvan to pursue my interest in the origins of cancer. I

Biography

I am a visual science communicator and create 3D molecular animations and immersive visualisation experiences to engage broad audiences more deeply in the important research endeavours at Garvan.

I practiced as a veterinarian before coming to Garvan to pursue my interest in the origins of cancer. I completed my PhD in cancer biology, signal transduction 2009, but it was during my PhD that I realised my passion was for communicating science. I then worked as a science writer and illustrator with Prof Sue Clark and the Epigenetics Research Laboratory at Garvan and also at the National Breast Cancer Foundation. In 2012 I was awarded an Inspiring Australia grant to produce 3D animations on cancer and epigenetics.

I create animations using authentic scientific data, and blend storytelling with the tools of art and design. My current focus is on creating multi-media animations and immersive visualisation experiences for Garvan’s Cell Observatory, an immersive visualisation dome and virtual reality via head mounted displays.

My research interests include animation and visualisation in education, and I use practice-led and reflective practice approaches to explore research questions related to the field of scientific visualisation and biomedical animation. .

I am a Lab Research Fellow in the 3D visualisation and Aesthetics Laboratory at UNSW Art and Design and a Conjoint Senior Lecturer at UNSW Sydney.

I am a visual science communicator and create 3D molecular animations and immersive visualisation experiences to engage broad audiences more deeply in the important research endeavours at Garvan.

I practiced as a veterinarian before coming to Garvan to pursue my interest in the origins of cancer. I completed my PhD in cancer biology, signal transduction 2009, but it was during my PhD that I realised my passion was for communicating science. I then worked as a science writer and illustrator with Prof Sue Clark and the Epigenetics Research Laboratory at Garvan and also at the National Breast Cancer Foundation. In 2012 I was awarded an Inspiring Australia grant to produce 3D animations on cancer and epigenetics.

I create animations using authentic scientific data, and blend storytelling with the tools of art and design. My current focus is on creating multi-media animations and immersive visualisation experiences for Garvan’s Cell Observatory, an immersive visualisation dome and virtual reality via head mounted displays.

My research interests include animation and visualisation in education, and I use practice-led and reflective practice approaches to explore research questions related to the field of scientific visualisation and biomedical animation. .

I am a Lab Research Fellow in the 3D visualisation and Aesthetics Laboratory at UNSW Art and Design and a Conjoint Senior Lecturer at UNSW Sydney.

Awards and Honours

2015 - Cancer Is Not One Disease animation project awarded as a top ten finalist in the International Science Visualisation Competition: National Science Foundation Vizzies.
2013 – Awarded Registered Biomedical Illustrator (RBI) with the Australian Institute of Medical and Biological Illustrators
2012 – Inspiring Australia Grant, an Australian Government Initiative

Education

2009 - PhD: Faculty of Medicine New South Wales University
Thesis title: Characterisation of the atypical dual specificity phosphatase DUSP26
Supervisors: Dr Philippa O’Brien (Cancer Program - Ovarian Cancer Group) and Professor Roger Daly (Cancer Program - Signal Transduction Group).
2004 – One year postgraduate clinical internship training program at the University of Sydney Teaching Hospital, Camden
2004 – Veterinary Science Post Graduate Foundation distance education course - Medical Oncology
1999 to 2003 - Bachelor of Veterinary Science, The University of Sydney

Selected Publications

Patterson K, Molecules do not have colour. The Conversation, Science and Technology; February 14 2017.

Patterson K, When process becomes product: re-packing visual science communication. The Conversation, Science and Technology; September 15 2016.

Patterson K, Science by stealth: secret missions of a visual science communicator. The Conversation, Science and Technology; July 21  2016.

Patterson K, Is photoshopping science universally wrong? The Conversation, Science and Technology; June 1 2016.

Patterson K, Shifting the field of view - science stories in virtual reality, The Conversation, Science and Technology; April 12 2016.

Patterson K, Talking serious science using scissors and glue, The Conversation, Science and Technology; February 25 2016.

Patterson K, Clark S. Art and Science Combine to Reveal the Inner Workings of Our DNA. The Conversation, Science and Technology; July 21 2015.

Patterson K, Tagging DNA: Mislabelling the Cancer Genome - Biomedical Animation published to the Garvan YouTube Channel. Duration: 03:15. 12 July 2015. 

Patterson K, VIZBIplus Visualising the Future of Biomedicine. Longnecker, C. Harris & K. Madden. (Eds.). 2015. Proceedings of the Australian Science Communicators National Conference. 2–5 Feb, 2014, Brisbane.  www.asc.asn.au/publications/

Patterson K, Cancer is Not One Disease - Biomedical Animation published to the Garvan Institute YouTube Channel. Duration 04:40. 9 April 2014.

Hulf T, Sibbritt T, Wiklund ED, Patterson K, Song JZ, Stirzaker C, Qu W, Nair S, Horvath LG, Armstrong NJ, Kench JG, Sutherland RL, Clark SJ. Epigenetic-induced repression of microRNA-205 is associated with MED1 activation and a poorer prognosis in localized prostate cancer. Oncogene. 2013; 32(23):2891-9.

Gloss BS, Patterson KI, Barton CA, Gonzalez M, Scurry JP, Hacker NF, Sutherland RL, O'Brien PM, Clark SJ. Integrative genome-wide expression and promoter DNA methylation profiling identifies a potential novel panel of ovarian cancer epigenetic biomarkers. Cancer Lett. 2012; 318(1):76-85.

Valdés-Mora F, Song JZ, Statham AL, Strbenac D, Robinson MD, Nair SS, Patterson KI, Tremethick DJ, Stirzaker C, Clark SJ. Acetylation of H2A.Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer. Genome Res. 2012; 22(2):307-21.

Devaney J, Stirzaker C, Qu W, Song JZ, Statham AL, Patterson KI, Horvath LG, Tabor B, Coolen MW, Hulf T, Kench JG, Henshall SM, Pe Benito R, Haynes AM, Mayor R, Peinado MA, Sutherland RL, Clark SJ. Epigenetic deregulation across chromosome 2q14.2 differentiates normal from prostate cancer and provides a regional panel of novel DNA methylation cancer biomarkers. Cancer Epidemiol Biomarkers Prev. 2011; 20(1):148-59.

Wang L, Chen H, Liu F, Madigan MC, Power CA, Hao J, Patterson KI, Pourgholami MH, O'Brien PM, Perkins AC, Li Y. Monoclonal antibody targeting MUC1 and increasing sensitivity to docetaxel as a novel strategy in treating human epithelial ovarian cancer. Cancer Lett. 2011; 300(2):122-33.

Patterson KI, Molloy L, Qu W, Clark SJ. DNA methylation: bisulphite modification and analysis. J Vis Exp. 2011; 56: e3170.
Patterson KI, Brummer T, Daly RJ, O'Brien PM. DUSP26 negatively affects the proliferation of epithelial cells, an effect not mediated by dephosphorylation of MAPKs. Biochim Biophys Acta. 2010; 1803(9):1003-12.

Wang L, Madigan MC, Chen H, Liu F, Patterson KI, Beretov J, O'Brien PM, Li Y. Expression of urokinase plasminogen activator and its receptor in advanced epithelial ovarian cancer patients. Gynecol Oncol. 2009; 114(2):265-72.

Patterson KI, Brummer T, O'Brien PM, Daly RJ. Dual-specificity phosphatases: critical regulators with diverse cellular targets. Biochem J. 2009; 418(3):475-89.

O'Brien PM, Davies MJ, Scurry JP, Smith AN, Barton CA, Henderson MJ, Saunders DN, Gloss BS, Patterson KI, Clancy JL, Heinzelmann-Schwarz VA, Murali R, Scolyer RA, Zeng Y, Williams ED, Scurr L, Defazio A, Quinn DI, Watts CK, Hacker NF, Henshall SM, Sutherland RL. The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro. Br J Cancer. 2009; 98(6):1085-93.