Our areas of research
Bone biology research
Our researchers use a variety of approaches to understand the fundamental basis for skeletal disorders. These include new screening techniques, advanced genetic analysis, the latest methods for working with the critical cells that maintain our skeletons, novel high-resolution microscopy to study individual bone cells in living tissues and sophisticated animal models of disease.
Cancer cells exhibit certain hallmarks that distinguish them from normal cells, including an unrestrained capacity to divide and the ability to spread throughout the body. The overall goal of the Cancer Research Division is to identify and describe the mechanisms that drive the development and progression of human cancers and to exploit this information to develop new biomarkers and therapeutic strategies.
Genomics and epigenetics
The fundamental goal of Genomics and Epigenetics Division is to understand genome biology and its impact on disease. Genomics is the study of information that is encoded within the full DNA sequence complement of an organism. Epigenetics is the study of how DNA is organised and regulated in the cell to promote a stably heritable phenotype without alterations in the DNA sequence.
The latest technologies are used to manipulate and analyse the behaviour of immune cells, both in the body and in the test tube. This includes sophisticated gene manipulation and analysis techniques, precise and detailed approaches for analysing the rare cell populations that initiate immune responses, and the capability to visualise individual cells - through powerful microscopes - as they function within the body.
Garvan’s Neuroscience researchers seek to understand the molecular mechanisms that underpin the capacity of the human brain to learn, think and function. This includes the ways nerve cells communicate with each other and what goes wrong in disorders such as neurodegenerative disease.
Diabetes and metabolism research
This research looks at the global rise of diabetes and obesity, and the part genetics and changes in our lifestyle and diet have played in this. Our teams are particularly interested in how fat and sugar contributes to diabetes, and how insulin fails to work properly in sufferers.
Diseases we research
By collaborating across different fields of research, we see a future where countless devastating diseases are no longer a death sentence. Through our never-ending pursuit of new discoveries, we see a future where medicine is revolutionized by understanding your DNA and treatment is personalized to you.