Peter Croucher manages a highly competitive research group with an international reputation for research in bone cell biology, tumour-induced bone disease and its clinical translation. This includes research into the understanding how tumours grow in bone and cause bone disease, particularly the haematological malignancy multiple myeloma, and breast and prostate cancer bone metastasis. This has been based on the development of some of the most robust experimental models available of cancers that grow in bone, particular models of tumour cell dormancy and activation. This work has been underpinned by ‘state of the art’ imaging technology, including two-photon intra-vital imaging, three-dimensional bioluminescence imaging and ex vivo and in vivo micro-CT imaging, along with detailed dynamic bone histomorphometric techniques.
In addition, Peter has research interests in the development of new high resolution screening techniques to identify new genes that regulate bone mass. He and his group aim to identify new genes, which can possibly represent new therapeutic targets for the treatment of osteoporosis and cancer-induced bone disease.
Peter is the one of the principle investigators on two major international collaborations; ProMis (Prostate Cancer Metastasis) (www.promis.org.au) and The Origins of Bone and Cartilage Disease Project (www.boneandcartilage.com). ProMis is a new collaborative prostate cancer research consortium dedicated to addressing the mechanisms behind, and ultimately developing new treatments for, lethal prostate cancer metastasis. The Origins of Bone and Cartilage Disease (OCBD) project is a collaboration which aims to identify genetic causes and identify the molecular mechanisms underlying the onset and progression of bone and cartilage disease. The project is focused on promoting scientific collaboration and research training in skeletal biology.
Peter plays an active role in research supervision. He has successfully supervised students for higher degrees and MSc and MPhil students. Peter’s research is currently funded by the Cancer Council, Cancer Research UK, the Wellcome Trust and the European Union.
In the News
New Osteoporosis National Action Plan Sets Out Vision to Tackle Major National Health Issue - Oct 20, 2016
Garvan student a double prizewinner at UNSW 3MT competition - Sep 09, 2016
Double award for Garvan Bone Biology researcher - Aug 31, 2016
Three Minute Thesis 2016: St Vincent’s Precinct competition takes place - Jun 16, 2016
Janet Watters, Dubbo Osteoporosis and Epidemiology Study Clinic Nurse, to retire after 24 years - Dec 15, 2015
How to wake a sleeping cancer cell – and why you might want to - Dec 04, 2015
Student success at EMBL Australia Symposium - Dec 01, 2015
Garvan gets behind Movember - Nov 05, 2015
Australians across the generations at risk with weak understanding of osteoporosis - Oct 20, 2015
Scott Youlten wins People’s Choice and ASPIRE award at the 2015 UNSW Interfaculty Final - Oct 20, 2015
Scott Youlten Wins 2015 UNSW Faculty of Medicine Three Minute Thesis Competition - Jul 07, 2015
Garvan led team wins prestigious prostate cancer award - Mar 13, 2014
Knockout finding reveals large number of genes that affect our bones - Aug 03, 2012