Cancer
Cancer cells exhibit certain hallmarks that distinguish them from normal cells, including an unrestrained capacity to divide and the ability to spread throughout the body. The overall goal of the Cancer Research theme is to identify and describe the mechanisms that drive the development and progression of human cancers and to exploit this information to develop new biomarkers and therapeutic strategies.
Our research is underpinned by extensive tissue banks, collected through local, national and international collaborations, as well as by databases that document relevant clinical and pathological information. The Breast, Prostate and Pancreatic Cancer tissue banks and databases rank among the best in the world.
The Kinghorn Cancer Centre, which houses many of the research labs and groups from the Cancer Research theme, aligns our research with best practice cancer services at St Vincent's Hospital, to facilitate rapid translation to the clinic and to develop innovative approaches in personalised medicine and improve outcomes for cancer patients.
Research Laboratories and Groups
Australian Pancreatic Genome Initiative Lab (Lab Head: Prof Anthony Gill)
Cancer Biology Lab (Lab Head: Prof Chris Ormandy)
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Tumour Development (Group Leader: Dr David Gallego-Ortega)
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Cell Survival Group (Group Leader: Dr Samantha Oakes)
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Replication and Genome Stability Group (Group Leader: Dr Liz Caldon)
Cancer Cell Plasticity Lab (Lab Head: A/Prof Christine Chaffer)
Connie Johnson Breast Cancer Research Lab (Lab Head: A/Prof Elgene Lim)
Genomic Cancer Medicine (Lab Head: Prof David Thomas)
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Immunobiology of Cancer Group (Group Leader: Dr Maya Kansara)
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Genetic Cancer Risk Group (Group Leader: Dr Mandy Ballinger)
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DNA and RNA Methodologies Group (Group Leader: Dr James (Jim) Blackburn)
Invasion and Metastasis Lab (Lab Head: Prof Paul Timpson)
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Matrix and Metastasis Group (Group Leader: A/Prof Thomas Cox)
Network Biology Lab (Lab Head: A/Prof David Croucher)
Personalised Cancer Therapeutics Lab (Lab Head: A/Prof Marina Pajic)
Single Cell and Computational Genomics Lab (Lab Head: Dr Joseph Powell)
Tumour Progression Lab (Lab Head: A/Prof Alex Swarbrick)
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Translational Breast Cancer Research Group (Group Leader: Prof Sandra O'Toole)
Clinical Prostate Cancer Research Group (Group Leader: Prof Lisa Horvath)
Genome Evolution Group (Group Leader: Prof Richard Epstein)
Hormones and Cancer Group (Group Leader: Dr Ann McCormack)