Dr Hui-Ming Lin

Research Officer

Hui-Ming completed her PhD degree at the University of Auckland in 2010. Her PhD thesis was about the metabolomic analysis of the interleukin-10 knockout mouse model of inflammatory bowel disease.

Prior to her PhD studies, she was an Assistant Research Fellow in the Cancer Genetics Laboratory, University of Otago, New Zealand, from 2004-2006.

Her current research at the Garvan Institute focuses on identifying therapeutic response biomarkers and elucidating the mechanisms of chemotherapy resistance in metastatic prostate cancer.

Research Interests

biomarker discovery
predicting and improving therapeutic response in prostate cancer
role of microRNAs in therapeutic response


2010 - PhD (Molecular Medicine), University of Auckland, New Zealand
2003 - MSc (Biochemistry), University of Canterbury, New Zealand
2000 - BSc (Biochemistry), University of Canterbury, New Zealand

Selected Publications

Lin H-M, Mahon KL, Spielman C, Gurney H, Mallesara G, Stockler MR, Bastick P, Briscoe K, Marx G, Swarbrick A, Horvath LG. Phase 2 study of circulating microRNA biomarkers in castration-resistant prostate cancer. Br J Cancer. 2017; 116 (8):1002-1011

Mahon KL, Lin H-M, Castillo L, Lee BY, Lee-Ng M, Chatfield MD, Chiam K, Breit SN, Brown DA, Molloy MP, Marx GM, Pavlakis N, Boyer MJ, Stockler MR, Daly RJ, Henshall SM, Horvath LG. Cytokine profiling of docetaxel-resistant castration-resistant prostate cancer. Br J Cancer. 2015; 112 (8):1340-1348 

Lin H-M, Castillo L, Mahon KL, Chiam K, Lee BY, Nguyen Q, Boyer MJ, Pavlakis N, Marx G, Mallesara G, Gurney H, Clark SJ, Swarbrick A, Daly RJ, Horvath LG. Circulating microRNAs are associated with docetaxel chemotherapy outcome in castration-resistant prostate cancer. Br J Cancer. 2014; 110(10):2462-2471

Lee BY, Hochgrafe F, Lin H-M, Castillo L, Wu J, Raftery MJ, Shreeve SM, Horvath LG, Daly RJ. Phosphoproteomic profiling identifies focal adhesion kinase as a mediator of docetaxel resistance in castrate-resistant prostate cancer. Mol Cancer Ther. 2014;13(1):190-201

Lin H-M, Barnett MP, Roy NC, Joyce NI, Zhu S, Armstrong K, Helsby NA, Ferguson LR, Rowan DD. Metabolomic analysis identifies inflammatory and noninflammatory metabolic effects of genetic modification in a mouse model of Crohn’s disease. J Proteome Res. 2010;9(4):1965-1975

Dr Hui-Ming Lin