KCCG’s nanopore sequencing service exists to support cutting-edge research projects in Australia and beyond. We are proud to say that our service contributed to the following studies published recently.
Genomics & epigenetics
Nanopore Sequencing Enables Comprehensive Transposable Element Epigenomic Profiling. Molecular Cell (2020).
https://doi.org/10.1016/j.molcel.2020.10.024
Canfam_GSD: De novo chromosome-length genome assembly of the German Shepherd Dog (Canis lupus familiaris) using a combination of long reads, optical mapping, and Hi-C. Gigascience (2020).
https://academic.oup.com/gigascience/article/9/4/giaa027/5813919
A universal and independent synthetic DNA ladder for the quantitative measurement of genomic features. Nature Communications (2020).
https://www.nature.com/articles/s41467-020-17445-5
Chiral DNA sequences as commutable controls for clinical genomics. Nature Communications (2019).
https://www.nature.com/articles/s41467-019-09272-0
Transcriptomics & RNA modifications
Accurate detection of m6A RNA modifications in native RNA sequences. Nature Communications (2019).
https://www.nature.com/articles/s41467-019-11713-9
High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes. Nature Communications (2019).
https://www.nature.com/articles/s41467-019-11049-4
Targeted, high-resolution RNA sequencing of non-coding genomic regions associated with neuropsychiatric functions. Frontiers in Genetics (2019).
https://www.frontiersin.org/articles/10.3389/fgene.2019.00309/full
Microbe, pathogen and metagenomics
Analytical validity of nanopore sequencing for rapid SARS-CoV-2 genome analysis. Nature Communications (2020).
https://www.nature.com/articles/s41467-020-20075-6
Single molecule, near full-length genome sequencing of dengue virus. Scientific Reports (2020)
https://www.nature.com/articles/s41598-020-75374-1
Unexpected host dependency of Antarctic Nanohaloarchaeota. PNAS (2019).
https://www.pnas.org/content/116/29/14661.abstract
Synthetic microbe communities provide internal reference standards for metagenome sequencing and analysis. Nature Communications (2018).
https://www.nature.com/articles/s41467-018-05555-0
Bioinformatics
Genopo: a nanopore sequencing analysis toolkit for portable Android devices. Communications Biology (2020)
https://www.nature.com/articles/s42003-020-01270-z
GPU accelerated adaptive banded event alignment for rapid comparative nanopore signal analysis. BMC Bioinformatics (2020).
https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-020-03697-x
Featherweight long read alignment using partitioned reference indexes. Scientific Reports (2019).
https://www.nature.com/articles/s41598-019-40739-8
SquiggleKit: a toolkit for manipulating nanopore signal data. Bioinformatics (2019).
https://academic.oup.com/bioinformatics/article/35/24/5372/5537108
