Recent studies

Links to recent studies supported by our sequencing services

KCCG’s nanopore sequencing service exists to support cutting-edge research projects in Australia and beyond. We are proud to say that our service contributed to the following studies published recently.

Genomics & epigenetics

Canfam_GSD: De novo chromosome-length genome assembly of the German Shepherd Dog (Canis lupus familiaris) using a combination of long reads, optical mapping, and Hi-C. Gigascience (2020).

https://academic.oup.com/gigascience/article/9/4/giaa027/5813919

A universal and independent synthetic DNA ladder for the quantitative measurement of genomic features. Nature Communications (2020).

https://www.nature.com/articles/s41467-020-17445-5

Chiral DNA sequences as commutable controls for clinical genomics. Nature Communications (2019).

https://www.nature.com/articles/s41467-019-09272-0

Transcriptomics & RNA modifications

Accurate detection of m6A RNA modifications in native RNA sequences. Nature Communications (2019).

https://www.nature.com/articles/s41467-019-11713-9

High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes. Nature Communications (2019).

https://www.nature.com/articles/s41467-019-11049-4

Targeted, high-resolution RNA sequencing of non-coding genomic regions associated with neuropsychiatric functions. Frontiers in Genetics (2019).

https://www.frontiersin.org/articles/10.3389/fgene.2019.00309/full

Microbe, pathogen and metagenomics

Unexpected host dependency of Antarctic Nanohaloarchaeota. PNAS (2019).

https://www.pnas.org/content/116/29/14661.abstract

Synthetic microbe communities provide internal reference standards for metagenome sequencing and analysis. Nature Communications (2018).

https://www.nature.com/articles/s41467-018-05555-0

Bioinformatics

Featherweight long read alignment using partitioned reference indexes. Scientific Reports (2019).

https://www.nature.com/articles/s41598-019-40739-8

SquiggleKit: a toolkit for manipulating nanopore signal data. Bioinformatics (2019).

https://academic.oup.com/bioinformatics/article/35/24/5372/5537108