KCCG’s nanopore sequencing service exists to support cutting-edge research projects in Australia and beyond. We are proud to say that our service contributed to the following studies published recently.
Genomics & epigenetics
Canfam_GSD: De novo chromosome-length genome assembly of the German Shepherd Dog (Canis lupus familiaris) using a combination of long reads, optical mapping, and Hi-C. Gigascience (2020).
A universal and independent synthetic DNA ladder for the quantitative measurement of genomic features. Nature Communications (2020).
Chiral DNA sequences as commutable controls for clinical genomics. Nature Communications (2019).
Transcriptomics & RNA modifications
Accurate detection of m6A RNA modifications in native RNA sequences. Nature Communications (2019).
High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes. Nature Communications (2019).
Targeted, high-resolution RNA sequencing of non-coding genomic regions associated with neuropsychiatric functions. Frontiers in Genetics (2019).
Microbe, pathogen and metagenomics
Unexpected host dependency of Antarctic Nanohaloarchaeota. PNAS (2019).
Synthetic microbe communities provide internal reference standards for metagenome sequencing and analysis. Nature Communications (2018).
Featherweight long read alignment using partitioned reference indexes. Scientific Reports (2019).
SquiggleKit: a toolkit for manipulating nanopore signal data. Bioinformatics (2019).