Clinical trials

Clinical trials are an essential part of our medical research.

We run a range of clinical trials for many diseases — see below for all current trials and ongoing programs. If appropriate, please consider participating: you'll be helping us create a healthier future for all.  

The benefits of clinical trials: 

  • enable deep insights and understanding of disease
  • identify new treatments and therapies
  • help decide government funding for new drugs.

All our trials adhere to strict protocols around safety, ethics and privacy.

MetMemory Study

An Australian-led research project at the Garvan Institute, funded by the National Health and Medical Research Council, is recruiting volunteers for a 3-year study examining the effects of metformin on cognition, brain anatomy and early signs of dementia.


We’re looking for people who meet the following eligibility criteria:

  • Live in the greater Sydney region;
  • Are over 60 years of age;
  • Are slightly overweight but do not have diabetes;
  • Do not have dementia;
  • Have concerns about changes in memory or thinking;
  • Are not currently taking metformin.
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Molecular screening and therapeutic trials (MoST)

The molecular screening and therapeutic trials (MoST) personalises experimental treatment based on an individual’s unique personal and cancer genetic profile, for patients with rare cancers.

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Personalised Medicine in Prediabetes (PREDICT)

The Personalised Medicine in Prediabetes – Towards Preventing Diabetes in Individuals at Risk (PREDICT) Study aims to test the efficacy of metformin administered with a personalised diet on blood sugar control in adults with prediabetes or early-stage type 2 diabetes.

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Australian Parkinson's Mission

The Australian Parkinson's Mission will conduct a clinical trial program using repurposed drugs, integrated with transformative research, to identify effective treatments for people with Parkinson’s. 

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Breast cancer clinical trials

Currently, there are a number of clinical trials running at the Kinghorn Cancer Centre for patients with early, advanced breast cancer and for patients undergoing breast cancer surgery. 

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Absorption of Ursolic acid in males

This trial aims to investigate the absorption profile of the nutritional supplement Ursolic acid. Studies in animals suggest it has the potential to help build muscle and prevent it from wasting away. Ursolic acid can be found in fruit and vegetables, however not much is absorbed. This study aims to determine the bio-availability, safety, and tolerability of ursolic acid.


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Insulin Resistance in Type 1 Diabetes managed with METformin (INTIMET study)

The INTIMET study aims to investigate the effects of metformin on hepatic and peripheral insulin resistance in adults with type 1 diabetes. 

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