Breast cancer clinical trials

Our researchers are conducting a number of clinical trials for breast cancer at the Kinghorn Cancer Centre. The current trials are looking for patients with early, advanced-stage breast cancer and patients that are undergoing breast cancer surgery. 

All trials are held at The Kinghorn Cancer Centre, Darlinghurst NSW.

Contact us for further information, to see if you're eligible for treatment, or to enquire about an upcoming trial.

Aura Serrano, Breast Cancer Clinical Research Nurse 
Email: aura.serrano@svha.org.au
Phone: 02 9355 5723 
Fax: 02 9355 5735

 

Early stage breast cancer

WinPro Study with prometrium (microionised progesterone)

A study of endocrine therapy with progesterone in post-menopausal women with early-stage hormone receptor positive breast cancer, prior to undergoing breast surgery.

Requirements: post-menopausal women with early-stage breast cancer which is estrogen and progesterone receptors positive, HER2 receptor negative, a tumour size of ≥1cm and have not yet had breast surgery.

Reference: HREC/17/SVH/255


GDC9545 window study 

A study of endocrine therapy with GDC 9545 (selective oestrogen receptor degrader) in post-menopausal women with early-stage hormone receptor positive breast cancer, prior to undergoing breast surgery

Requirements: post-menopausal women with early-stage breast cancer which is estrogen receptor positive, HER2 receptor negative, a tumour size of ≥1cm and have not yet had breast surgery.

Reference: HREC/eth00224


Exercise during chemotherapy study

A study of exercise during chemotherapy for breast cancer given prior to surgery (Neoadjuvant or preoperative chemotherapy). We will provide patients with a personalised exercise program and study the effects of exercise on the tumour at the time of surgery.

Requirements: patients with early-stage breast cancer who have their chemotherapy prior to surgery.

Reference: HREC/16/SVH/334


 

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Advanced stage breast cancer

A selective estrogen receptor degrader study for ER positive breast cancer

A study of GDC-9545 alone or in combination with palbociclib (Ibrance) and goserelin (Zoladex) for advanced breast cancer.

Requirements: patients with advanced breast cancer, which is estrogen receptor positive and HER2 receptor negative.

Reference: HREC/17/PMCC/158


A novel selective estrogen receptor degrader for ER positive breast cancer

A study of LY3484356 alone or in combination with abemaciclib for women with advanced breast cancer

Reference: HREC/Pending 


Patina study with palbociclib (Ibrance, a CDK4/6 inhibitor)

A study of palbociclib (Ibrance) with trastuzumab (Herceptin), pertuzumab (Perjeta) and endocrine therapy for patients with advanced breast cancer.

Requirements: patients with advanced breast cancer which is estrogen and HER2 receptors positive, and have not received prior treatment for metastatic disease.

Reference: HREC/17/SVH/141


 

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All patients undergoing breast surgery at St Vincent's Hospital

Project SHARE (Specimens Help All Research Efforts)

We invite all patients undergoing breast surgery at St Vincent’s Hospital to partner with us in our research endeavours. Tissue that is routinely collected at the time of surgery and in excess of diagnostic requirements will be brought to the laboratories at the Garvan Institute, enabling many researchers use these tissues as building blocks for their research.