B cells race the clock to get a second wind
Co-stimulatory second signals delivered through TLRs or CD40 rescue antigen-stimulated B cells from metabolic dysfunction and apoptosis. This identifies a critical time-limited window during which B cells integrate sequential signals to successfully initiate humoral immunity.
|ISBN||1529-2916 (Electronic) 1529-2908 (Linking)|
|Authors||Phan, T. G.; Tangye, S. G.|
|Responsible Garvan Author|
|Publisher Name||NATURE IMMUNOLOGY|
|URL link to publisher's version||https://www.ncbi.nlm.nih.gov/pubmed/29988092|