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Vitamin D and the Liver-Correlation or Cause?


Vitamin D is becoming increasingly accepted as an important physiological regulator outside of its classical role in skeletal homeostasis. A growing body of evidence connects vitamin D with hepatic disease. This review summarises the role of vitamin D in liver homeostasis and disease and discusses the therapeutic potential of vitamin D-based treatments to protect against hepatic disease progression and to improve response to treatment. While pre-clinical experimental data is promising, clinical trials around liver diseases have mostly been under-powered, and further studies will be required to clarify whether vitamin D or vitamin D analogues have beneficial effects on liver disease.

Type Journal
ISBN 2072-6643 (Electronic) 2072-6643 (Linking)
Authors Keane, J. T.; Elangovan, H.; Stokes, R. A.; Gunton, J. E.
Responsible Garvan Author (missing name)
Publisher Name Nutrients
Published Date 2018-04-01
Published Volume 10
Published Issue 4
Status Always Electronic
DOI 10.3390/nu10040496
URL link to publisher's version