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Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody
Singh, M.; Jackson, K. J. L.; Wang, J. J.; Schofield, P.; Field, M. A.; Koppstein, D.; Peters, T. J.; Burnett, D. L.; Rizzetto, S.; Nevoltris, D.; Masle-Farquhar, E.; Faulks, M. L.; Russell, A.; Gokal, D.; Hanioka, A.; Horikawa, K.; Colella, A. D.; Chataway, T. K.; Blackburn, J.; Mercer, T. R.; Langley, D. B.; Goodall, D. M.; Jefferis, R.; Gangadharan Komala, M.; Kelleher, A. D.; Suan, D.; Rischmueller, M.; Christ, D.; Brink, R.; Luciani, F.; Gordon, T. P.; Goodnow, C. C.; Reed, J. H.
CELL 180 :1*17, 2020 10.1016/j.cell.2020.01.029
Fluids and their mechanics in tumour transit: shaping metastasis
Follain, G.; Herrmann, D.; Harlepp, S.; Hyenne, V.; Osmani, N.; Warren, S. C.; Timpson, P.; Goetz, J. G.
NATURE REVIEWS CANCER 20 (2) :107-124, 2020 10.1038/s41568-019-0221-x
Should the cardio-protective properties of sodium-glucose cotransporter 2 inhibitors dictate therapeutic decision-making in patients with type 2 diabetes
Milder, T. Y.; Day, R. O.; Stocker, S. L.; Greenfield, J. R.
INTERNAL MEDICINE JOURNAL 50 (5) :645-646, 2020 10.1111/imj.14819
Activated PI3Kdelta breaches multiple B cell tolerance checkpoints and causes autoantibody production
Lau, A.; Avery, D. T.; Jackson, K.; Lenthall, H.; Volpi, S.; Brigden, H.; Russell, A. J.; Bier, J.; Reed, J. H.; Smart, J. M.; Cole, T.; Choo, S.; Gray, P. E.; Berglund, L. J.; Hsu, P.; Wong, M.; O'Sullivan, M.; Boztug, K.; Meyts, I.; Uzel, G.; Notarangelo, L. D.; Brink, R.; Goodnow, C. C.; Tangye, S. G.; Deenick, E. K.
JOURNAL OF EXPERIMENTAL MEDICINE 217 (2) 2020 10.1084/jem.20191336
Who should access germline genome sequencing? A mixed methods study of patient views
Best, M. C.; Butow, P.; Jacobs, C.; Savard, J.; Biesecker, B.; Ballinger, M. L.; Bartley, N.; Davies, G.; Napier, C. E.; Smit, A. K.; Thomas, D. M.; Newson, A. J.; Members of the PiGeOn Project, .
CLINICAL GENETICS 97 (2) :329-337, 2020 10.1111/cge.13664
Differential methylation pattern of xenobiotic metabolizing genes and susceptibility to Balkan endemic nephropathy, in a cohort of Romanian patients
Ivan, A.; Lam, D.; Cristea, M. I.; Telea, A.; Gruia, A. T.; Oprean, C.; Margineanu, F.; Bojin, F. M.; Saffery, R.; Paunescu, V.; Tatu, C. A.
JOURNAL OF NEPHROLOGY 2020 10.1007/s40620-019-00621-2
Human inborn errors of immunity to herpes viruses
Emmanuelle Jouanguy, Vivien BA(c)ziat, Trine HMogensen, Jean-LaurentCasanova, Stuart GTangye, Shen-YingZhang
CURRENT OPINION IN IMMUNOLOGY 62 :106-122, 2020 https://doi.org/10.1016/j.coi.2020.01.004
MCL-1 antagonism enhances the anti-invasive effects of dasatinib in pancreatic adenocarcinoma
Castillo, L.; Young, A. I. J.; Mawson, A.; Schafranek, P.; Steinmann, A. M.; Nessem, D.; Parkin, A.; Johns, A.; Chou, A.; Law, A. M. K.; Lucas, M. C.; Murphy, K. J.; Deng, N.; Gallego-Ortega, D.; Caldon, C. E.; Australian Pancreatic Cancer Genome, Initiative; Timpson, P.; Pajic, M.; Ormandy, C. J.; Oakes, S. R.
ONCOGENE 39 (8) :1821-1829, 2020 10.1038/s41388-019-1091-0
Exploring the role of novel medical therapies for aggressive pituitary tumors: A review of the literature -"Are We There Yet?"
Lamb, L. S.; Sim, H. W.; McCormack, A. I.
Cancers 12 (2) :308, 2020 10.3390/cancers12020308
Pharmacodynamics effects of CDK4/6 inhibitor LEE011 (ribociclib) in high-risk, localised prostate cancer: a study protocol for a randomised controlled phase II trial (LEEP study: LEE011 in high-risk, localised Prostate cancer)
Scheinberg, T.; Kench, J.; Stockler, M.; Mahon, K. L.; Sebastian, L.; Stricker, P.; Joshua, A. M.; Woo, H.; Thanigasalam, R.; Ahmadi, N.; Centenera, M. M.; Butler, L. M.; Horvath, L. G.
BMJ Open 10 (1) :e033667, 2020 10.1136/bmjopen-2019-033667
The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly
Mark Pinese, Paul Lacaze, Emma M. Rath, Andrew Stone, Marie-Jo Brion, Adam Ameur, Sini Nagpal, Clare Puttick, Shane Husson, Dmitry Degrave, Tina Navin Cristina, Vivian F. S. Kahl, Aaron L. Statham, Robyn L. Woods, John J. McNeil, Moeen Riaz, Margo Barr, Mark R. Nelson, Christopher M. Reid, Anne M. Murray, Raj C. Shah, Rory Wolfe, Joshua R. Atkins, Chantel Fitzsimmons, Heath M. Cairns, Melissa J. Green, Vaughan J. Carr, Mark J. Cowley, Hilda A. Pickett, Paul A. James, Joseph E. Powell, Warren Kaplan, Greg Gibson, Ulf Gyllensten, Murray J. Cairns, Martin McNamara, Marcel E. Dinger & David M. Thomas
Nature Communications 11 (1) :435, 2020 10.1038/s41467-019-14079-0
The safety and pharmacokinetics of metformin in patients with chronic liver disease
Smith, F. C.; Stocker, S. L.; Danta, M.; Carland, J. E.; Kumar, S. S.; Liu, Z.; Greenfield, J. R.; Braithwaite, H. E.; Cheng, T. S.; Graham, G. G.; Williams, K. M.; Day, R. O.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS 2020 10.1111/apt.15635
Reductions in skeletal muscle mitochondrial mass are not restored following exercise training in patients with chronic kidney disease
Watson, E. L.; Baker, L. A.; Wilkinson, T. J.; Gould, D. W.; Graham-Brown, M. P. M.; Major, R. W.; Ashford, R. U.; Philp, A.; Smith, A. C.
FASEB JOURNAL 34 (1) :1755-1767, 2020 10.1096/fj.201901936RR
The role of the extracellular matrix and the heparan sulfate proteoglycan Perlecan
Elgundi, Z.; Papanicolaou, M.; Major, G.; Cox, T. R.; Melrose, J.; Whitelock, J. M.; Farrugia, B. L.
Frontiers in Oncology 9 :1482, 2020 10.3389/fonc.2019.01482
Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer
Achinger-Kawecka, J.; Valdes-Mora, F.; Luu, P. L.; Giles, K. A.; Caldon, C. E.; Qu, W.; Nair, S.; Soto, S.; Locke, W. J.; Yeo-Teh, N. S.; Gould, C. M.; Du, Q.; Smith, G. C.; Ramos, I. R.; Fernandez, K. F.; Hoon, D. S.; Gee, J. M. W.; Stirzaker, C.; Clark, S. J.
Nature Communications 11 (1) :320, 2020 10.1038/s41467-019-14098-x