5594 items matching your search terms.
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Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody
- Singh, M.; Jackson, K. J. L.; Wang, J. J.; Schofield, P.; Field, M. A.; Koppstein, D.; Peters, T. J.; Burnett, D. L.; Rizzetto, S.; Nevoltris, D.; Masle-Farquhar, E.; Faulks, M. L.; Russell, A.; Gokal, D.; Hanioka, A.; Horikawa, K.; Colella, A. D.; Chataway, T. K.; Blackburn, J.; Mercer, T. R.; Langley, D. B.; Goodall, D. M.; Jefferis, R.; Gangadharan Komala, M.; Kelleher, A. D.; Suan, D.; Rischmueller, M.; Christ, D.; Brink, R.; Luciani, F.; Gordon, T. P.; Goodnow, C. C.; Reed, J. H.
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CELL
180
:1*17,
2020
10.1016/j.cell.2020.01.029
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Fluids and their mechanics in tumour transit: shaping metastasis
- Follain, G.; Herrmann, D.; Harlepp, S.; Hyenne, V.; Osmani, N.; Warren, S. C.; Timpson, P.; Goetz, J. G.
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NATURE REVIEWS CANCER
20
(2)
:107-124,
2020
10.1038/s41568-019-0221-x
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Should the cardio-protective properties of sodium-glucose cotransporter 2 inhibitors dictate therapeutic decision-making in patients with type 2 diabetes
- Milder, T. Y.; Day, R. O.; Stocker, S. L.; Greenfield, J. R.
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INTERNAL MEDICINE JOURNAL
50
(5)
:645-646,
2020
10.1111/imj.14819
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Activated PI3Kdelta breaches multiple B cell tolerance checkpoints and causes autoantibody production
- Lau, A.; Avery, D. T.; Jackson, K.; Lenthall, H.; Volpi, S.; Brigden, H.; Russell, A. J.; Bier, J.; Reed, J. H.; Smart, J. M.; Cole, T.; Choo, S.; Gray, P. E.; Berglund, L. J.; Hsu, P.; Wong, M.; O'Sullivan, M.; Boztug, K.; Meyts, I.; Uzel, G.; Notarangelo, L. D.; Brink, R.; Goodnow, C. C.; Tangye, S. G.; Deenick, E. K.
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JOURNAL OF EXPERIMENTAL MEDICINE
217
(2)
2020
10.1084/jem.20191336
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Who should access germline genome sequencing? A mixed methods study of patient views
- Best, M. C.; Butow, P.; Jacobs, C.; Savard, J.; Biesecker, B.; Ballinger, M. L.; Bartley, N.; Davies, G.; Napier, C. E.; Smit, A. K.; Thomas, D. M.; Newson, A. J.; Members of the PiGeOn Project, .
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CLINICAL GENETICS
97
(2)
:329-337,
2020
10.1111/cge.13664
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Differential methylation pattern of xenobiotic metabolizing genes and susceptibility to Balkan endemic nephropathy, in a cohort of Romanian patients
- Ivan, A.; Lam, D.; Cristea, M. I.; Telea, A.; Gruia, A. T.; Oprean, C.; Margineanu, F.; Bojin, F. M.; Saffery, R.; Paunescu, V.; Tatu, C. A.
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JOURNAL OF NEPHROLOGY
2020
10.1007/s40620-019-00621-2
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Human inborn errors of immunity to herpes viruses
- Emmanuelle Jouanguy, Vivien BA(c)ziat, Trine HMogensen, Jean-LaurentCasanova, Stuart GTangye, Shen-YingZhang
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CURRENT OPINION IN IMMUNOLOGY
62
:106-122,
2020
https://doi.org/10.1016/j.coi.2020.01.004
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MCL-1 antagonism enhances the anti-invasive effects of dasatinib in pancreatic adenocarcinoma
- Castillo, L.; Young, A. I. J.; Mawson, A.; Schafranek, P.; Steinmann, A. M.; Nessem, D.; Parkin, A.; Johns, A.; Chou, A.; Law, A. M. K.; Lucas, M. C.; Murphy, K. J.; Deng, N.; Gallego-Ortega, D.; Caldon, C. E.; Australian Pancreatic Cancer Genome, Initiative; Timpson, P.; Pajic, M.; Ormandy, C. J.; Oakes, S. R.
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ONCOGENE
39
(8)
:1821-1829,
2020
10.1038/s41388-019-1091-0
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Exploring the role of novel medical therapies for aggressive pituitary tumors: A review of the literature -"Are We There Yet?"
- Lamb, L. S.; Sim, H. W.; McCormack, A. I.
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Cancers
12
(2)
:308,
2020
10.3390/cancers12020308
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Pharmacodynamics effects of CDK4/6 inhibitor LEE011 (ribociclib) in high-risk, localised prostate cancer: a study protocol for a randomised controlled phase II trial (LEEP study: LEE011 in high-risk, localised Prostate cancer)
- Scheinberg, T.; Kench, J.; Stockler, M.; Mahon, K. L.; Sebastian, L.; Stricker, P.; Joshua, A. M.; Woo, H.; Thanigasalam, R.; Ahmadi, N.; Centenera, M. M.; Butler, L. M.; Horvath, L. G.
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BMJ Open
10
(1)
:e033667,
2020
10.1136/bmjopen-2019-033667
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The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly
- Mark Pinese, Paul Lacaze, Emma M. Rath, Andrew Stone, Marie-Jo Brion, Adam Ameur, Sini Nagpal, Clare Puttick, Shane Husson, Dmitry Degrave, Tina Navin Cristina, Vivian F. S. Kahl, Aaron L. Statham, Robyn L. Woods, John J. McNeil, Moeen Riaz, Margo Barr, Mark R. Nelson, Christopher M. Reid, Anne M. Murray, Raj C. Shah, Rory Wolfe, Joshua R. Atkins, Chantel Fitzsimmons, Heath M. Cairns, Melissa J. Green, Vaughan J. Carr, Mark J. Cowley, Hilda A. Pickett, Paul A. James, Joseph E. Powell, Warren Kaplan, Greg Gibson, Ulf Gyllensten, Murray J. Cairns, Martin McNamara, Marcel E. Dinger & David M. Thomas
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Nature Communications
11
(1)
:435,
2020
10.1038/s41467-019-14079-0
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The safety and pharmacokinetics of metformin in patients with chronic liver disease
- Smith, F. C.; Stocker, S. L.; Danta, M.; Carland, J. E.; Kumar, S. S.; Liu, Z.; Greenfield, J. R.; Braithwaite, H. E.; Cheng, T. S.; Graham, G. G.; Williams, K. M.; Day, R. O.
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ALIMENTARY PHARMACOLOGY & THERAPEUTICS
2020
10.1111/apt.15635
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Reductions in skeletal muscle mitochondrial mass are not restored following exercise training in patients with chronic kidney disease
- Watson, E. L.; Baker, L. A.; Wilkinson, T. J.; Gould, D. W.; Graham-Brown, M. P. M.; Major, R. W.; Ashford, R. U.; Philp, A.; Smith, A. C.
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FASEB JOURNAL
34
(1)
:1755-1767,
2020
10.1096/fj.201901936RR
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The role of the extracellular matrix and the heparan sulfate proteoglycan Perlecan
- Elgundi, Z.; Papanicolaou, M.; Major, G.; Cox, T. R.; Melrose, J.; Whitelock, J. M.; Farrugia, B. L.
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Frontiers in Oncology
9
:1482,
2020
10.3389/fonc.2019.01482
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Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer
- Achinger-Kawecka, J.; Valdes-Mora, F.; Luu, P. L.; Giles, K. A.; Caldon, C. E.; Qu, W.; Nair, S.; Soto, S.; Locke, W. J.; Yeo-Teh, N. S.; Gould, C. M.; Du, Q.; Smith, G. C.; Ramos, I. R.; Fernandez, K. F.; Hoon, D. S.; Gee, J. M. W.; Stirzaker, C.; Clark, S. J.
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Nature Communications
11
(1)
:320,
2020
10.1038/s41467-019-14098-x