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Prostate cancer
Jun 13, 2007 09:58 AM
Get the facts on prostate cancer, symptoms, diagnosis and treatment. Garvan's research is focused on genetic differences, tailored treatment options and quality of life in those affected.
Functional significance and clinical phenotype of nontruncat...
May 08, 2013 12:45 PM
BACKGROUND & AIMS: Germline mutations in mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer. A significant proportion of mutations are nontruncating and associated with a variability of c...
‘Connie’s Heart’ raises $110,000 for cancer research
Oct 31, 2017 04:30 PM
The large-scale artwork ‘Connie’s Heart’, by Marie Ramos, has this week been unveiled at Garvan by Samuel Johnson OAM. Inspired by Connie Johnson and Love Your Sister, the artwork was a year in the making and has r...
AIMS/HYPOTHESIS: Administration of anti-CD40 ligand (CD40L) antibodies has been reported to allow long-term islet allograft survival in non-human primates without the need for exogenous immunosuppression. However, the us...
BACKGROUND: The 46,XY female is characterised by a male karyotype and female phenotype arising due to any interruption in the sexual development pathways in utero. The cause is usually genetic and various genes are impli...
Vitamin D receptor gene polymorphisms and the risk of fractu...
May 08, 2013 12:45 PM
The association between vitamin D receptor gene polypmorphisms and bone mineral density is controversial. The relationship between vitamin D receptor genotype and risk of fracture is uncertain. To determine whether vitam...
Scientific output and its relationship to knowledge economy:...
May 08, 2013 12:46 PM
Human growth hormone production from a recombinant mammalian...
May 08, 2013 12:44 PM
Relationship between cytoplasmic pH and proliferation during...
May 08, 2013 12:44 PM
Flow cytometry was used to measure intracellular pH (pHi) on an individual cell basis during exponential and plateau phases of growth. In all three cell lines examined a range of pHi values was associated with exponentia...
Interleukin-6 increases insulin-stimulated glucose disposal ...
May 08, 2013 12:45 PM
Although interleukin-6 (IL-6) has been associated with insulin resistance, little is known regarding the effects of IL-6 on insulin sensitivity in humans in vivo. Here, we show that IL-6 infusion increases glucose dispos...
The mutated in colorectal cancer (MCC) is a multifunctional gene showing loss of expression in colorectal and liver cancers. MCC mutations can drive colon carcinogenesis in the mouse and in vitro experiments suggest that...
OBJECTIVES: Immune checkpoint blockade using inhibitors of programmed death-1 have shown promise in early phase clinical trials in NSCLC and programmed death-ligand 1 (PD-L1) tumoral expression could potentially be a use...
Short-term overfeeding may induce peripheral insulin resista...
May 08, 2013 12:46 PM
OBJECTIVE: Chronic low-grade inflammation is a feature of obesity and is postulated to be causal in the development of insulin resistance and type 2 diabetes. The aim of this study was to assess whether overfeeding induc...
Tissue specific and vitamin D responsive gene expression in ...
May 08, 2013 12:45 PM
Studies of gene expression in bone have adopted a number of molecular approaches that seek to determine those cis and trans-acting factors responsible for the development and physiological regulation of this unique tissu...
Growth hormone in exercise: comparison of physiological and ...
May 08, 2013 12:44 PM
This study was designed to compare the serum growth hormone (GH) response with quantified exercise to that obtained with other stimuli. In eight normal males, aged 21-24 yr, we studied the serum GH response to 20 min cyc...
Primary adrenal tumours--a ten-year experience
May 08, 2013 12:44 PM
The experience of 31 patients with primary adrenal tumours seen in one teaching hospital over a 10-year period is reviewed. There were 10 patients who had benign cortical adenomas; 11 had adrenal cortical carcinomas, and...
