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Secretory phospholipase A2 and lipoprotein lipase enhance 15...
May 08, 2013 12:45 PM
The oxidation of low-density lipoprotein (LDL) is thought to contribute to atherogenesis. 15-Lipoxygenase (15LO) induces LDL oxidation, and phospholipase A2 enhances this process [Sparrow, C. P. , Parthasarathy, S., and ...
The measurement of IgE in asthma by a new radioimmunoassay
May 08, 2013 12:44 PM
Mechanisms of cyclin-dependent kinase inactivation by proges...
May 08, 2013 12:45 PM
The steroid hormone progesterone regulates proliferation and differentiation in the mammary gland and uterus by cell cycle phase-specific actions. In breast cancer cells the predominant effect of synthetic progestins is ...
Adhesion Molecules and Chemoattratants in the Pathogenesis a...
May 08, 2013 12:45 PM
A Western Australian kindred with Dutch cerebral amyloid ang...
May 08, 2013 12:45 PM
A family from the south of Western Australia is described with Dutch cerebral amyloid angiopathy (HCHWA-D). The proband died at age 60 from recurrent lobar haemorrhages in the brain, as did his sister and five other fami...
Vitamin D deficiency promotes prostate cancer growth in bone...
May 08, 2013 12:46 PM
BACKGROUND: Vitamin D is considered as an important determinant of bone turnover as well as cancer growth. Using a murine model of bone metastasis, we investigated the effect of vitamin D deficiency on prostate cancer ce...
Genetic determinants of bone mass
May 08, 2013 12:45 PM
PURPOSE OF REVIEW: This review examines recent advances in the analysis of genetic determinants of bone mass. It addresses both human and animal linkage studies as well as genetic manipulations in animals, inbred mouse m...
The pharmacokinetics, safety and endocrine effects of authen...
May 08, 2013 12:44 PM
The pharmacokinetics, safety and endocrine effects of an authentic human growth hormone (bio-hGH), produced by the expression of genomic hGH in a mammalian cell line, were studied in six healthy young men who were admini...
BACKGROUND: Ipilimumab (Yervoy; Bristol-Myers Squibb) is a novel fully humanised monoclonal antibody that blocks cytotoxic T-lymphocyte antigen 4 (CTLA-4), an immune checkpoint molecule, to augment anti-tumour T-cell res...
Fat oxidation, body composition and insulin sensitivity in d...
May 08, 2013 12:45 PM
OBJECTIVE: To investigate whether normal glucose-tolerant and type II diabetic overweight adults differ in response to weight regain with regard to substrate oxidation and metabolic parameters. METHODS: A total of 15 ove...
Hypopituitarism - pituitary disease and intrinsic hypothal...
May 08, 2013 12:45 PM
BACKGROUND: In microbeam radiotherapy (MRT), parallel arrays of high-intensity synchrotron x-ray beams achieve normal tissue sparing without compromising tumor control. Grid-therapy using clinical linacs has spatial modu...
Logic and extent of miRNA-mediated control of autoimmune gen...
May 08, 2013 12:46 PM
Over the past few decades, multiple mechanisms have emerged that operate to prune the lymphocyte repertoire of self-reactive specificities and maintain immunological tolerance. Multiple families of small noncoding RNAs k...
BACKGROUND: Esophageal and gastroesophageal junctional (GEJ) adenocarcinoma is one of the most fatal cancers and has the fastest rising incidence rate of all cancers. Identification of biomarkers is needed to tailor trea...
Bone mineral density in prepubertal asthmatics receiving cor...
May 08, 2013 12:45 PM
OBJECTIVE: To examine whether bone mass is reduced in prepubertal, asthmatics receiving high doses of inhaled corticosteroids. METHODOLOGY: A cross-sectional comparison of lumbar spine-bone mineral density (LS-BMD) was u...
Physical exercise, genetics and bone mass
May 08, 2013 12:44 PM
