Garvan scientists have shown that brown fat – a special type of fat that burns energy to keep us warm – may also help to keep blood sugar steady in adults. Their findings suggest new avenues for diabetes therapies that target brown fat.
Exploring the paradox of metabolically healthy obesity
Australian researchers have defined some key characteristics of the metabolically healthy obese – those obese individuals who remain free from type 2 diabetes and other disorders that usually associate with obesity. Their findings have implications for the treatment of type 2 diabetes, insulin resistance and obesity.
Measuring distress in people with Types 1 and 2 diabetes
Diabetes experts, psychiatrists and neuroscientists have reported the benefits of measuring depression and disease-related distress in patients with diabetes. They have also shown that distress is influenced by heritable genetic changes in the way patients’ bodies handle serotonin, a neurotransmitter that regulates mood.
Garvan scientists believe they have identified an enzyme that undermines a delicately balanced whole-body system that keeps blood sugar levels stable and low in healthy people. The collapse of this system in the pancreas, the liver and muscle leads to diabetes.
How fat might be controlled through the body clock
Garvan researchers have shed more light on an underexplored aspect of the important brain-signaling system that controls appetite, body composition and energy use. Their findings suggest that a specific gene regulating our body clock may play a central role in determining how fat we become.
Diabetes Australia recognition for Garvan researcher
Garvan congratulates Dr Dorit Samocha-Bonet (Diabetes and Metabolism Division), who has been awarded the 2016 ADS Diabetes Australia Research Grant in support of her research into body acidity and insulin resistance.