Guillain-Barré syndrome

Guillain-Barré syndrome is an autoimmune disorder where the immune system attacks the nerves that come out from the spinal cord.

What is Guillain-Barré syndrome?

People with Guillain-Barré syndrome (GBS) generally have muscle weakness or paralysis as well as some odd sensations like pins and needles. Most people with GBS recover fully, though some rehabilitation may be needed. A small percentage may be left with permanent disabilities.

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Key statistics

30-50

30-50

Most people diagnosed are between 30 to 50 years old, though GBS can affect all ages and genders.

2-8

2-8

Between 2 to 8 people in every 100,000 will develop GBS.

10-15%

10-15%

10-15% of cases will need long-term rehabilitation and experience permanent disabilities.

Guillain-Barré research at Garvan

We look at how infections can cause an autoimmune response, a peculiar mechanism that's not well understood. We're examining the underlying causes of GBS by using cellular genomics to study immune cells, and what happens during an autoimmune attack.

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