Tools & services

Resources created by the BioVis Centre

Help with your data

Contact us if you need help with large, complex, or highly-multidimensional datasets. We have a sustained track record in creating world-leading solutions for deriving insight from challenging data (e.g., see tools listed below). We can provide training, consultation, and advice on best practises in the visual analysis of a wide variety of data, but especially data related to biological or biomedical research. We are most interested in cases where current methods for visual or automated analysis are inadequate (e.g., single-cell or single-molecule sequencing data), often requiring the invention of new, visual paradigms. Finally, we can help implement web-based, visual analysis tools that enable interactive data exploration, and accelerate discovery of insights buried in complex datasets.

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Aquaria

Atomic-resolution 3D structures are now known for thousands of proteins, providing insight into the molecular processes of life and disease. Unfortunately, many scientists miss these insights due to difficulties finding and using biomolecular structures. Aquaria helps by providing: (1) a concise visual summary of all 3D structural data related to any (SwissProt) protein sequence; and (2) an easy way to map sequence features (SNPs, PTMs, etc.) onto any related 3D structure.

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Group18

The five noble gases (helium, neon, argon, krypton, and xenon) have diverse biological properties, including an expanding range of clinical effects, such as anaesthesia, amelioration of ischemic damage, tissue protection prior to transplantation, and analgesic properties. The Group18 website helps biomedical researchers find new therapeutic uses for noble gases by showing where each noble gas is likely to interact within all currently know 3D structures of proteins.

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Minardo

Our cells constantly respond to external signals; many responses involve thousands of distinct modifications to the transcriptome or proteome (e.g., phosphorylation). Recent advances allow these modifications to be tracked, providing unprecedented detail into the molecular processes of life and disease; however, gaining insight from these complex datasets remains challenging. Minardo helps by providing a layout strategy for visually organising cellular events to clearly reveal casual relationships.

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Rondo

Genomics is rapidly becoming a core technology in society. However, our understanding of the genome is currently limited by lack of knowledge about how chromosomes are organised in 3D. A first glimpse in this organisation is provided by 'HiC', a recent experimental technique that can detect pairs of chromosomal regions within close spatial proximity. These experiments generate billions of 3D contacts, thus are challenging to interpret. Rondo helps by allowing intuitive exploration of HiC data, in combination with sequence features (e.g., genes, epigenomic marks).

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VIZBI

In the life sciences, visualisation is becoming increasingly important due to rapid growth in data volume and complexity. In computer science, many advanced visualization methods are being developed; unfortunately, adoption of these methods is impeded by the fact that scientists from these two communities rarely attend each other’s conferences. To address this, the VIZBI initiative was launched in 2010 to improve the global standard of data visualization in the life sciences.

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