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Dr Joanna Achinger-Kawecka

Joanna completed her PhD on the identification of microRNAs for the prediction of breast cancer treatment outcome at the Dr. Margarete-Fischer-Bosch-Institute of Clinical Pharmacology (IKP) in Stuttgart, Germany in late 2013 and then moved to Australia to join the Epigenetics Research group at the G
Research Officer

Conjoint/Adjunct Role(s)

Conjoint Associate Lecturer, St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney

Joanna completed her PhD on the identification of microRNAs for the prediction of breast cancer treatment outcome at the Dr. Margarete-Fischer-Bosch-Institute of Clinical Pharmacology (IKP) in Stuttgart, Germany in late 2013 and then moved to Australia to join the Epigenetics Research group at the Garvan Institute. Her current research interests include studying the role of three-dimensional (3D) genome organization in cancer and identification of mechanisms by which chromatin architecture arises and is maintained in normal and cancer cells.

Research Interests

Epigenetic deregulation in cancer
Three-dimensional genome in normal and cancer biology
Chromatin organization
Chromosome Conformation Capture

Awards and Honours

2017 - The Ian Potter Foundation Travel Grant
2016 - Best Postdoc Poster Prize, 24th St Vincent’s Campus Research Symposium
2016 - Heliflite Young Explorer Award
2015 - Best Oral Presentation Prize, 23rd St Vincent’s Campus Research Symposium
2011 – FP7 Marie Curie Initial Training Network “Fighting Drug Failure” Fellowship

Education

2014 – PhD (Pharmaceutical Sciences), Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology and University Tuebingen - Germany
2011 – MSc (Biotechnology), Warsaw University of Life Sciences - Poland

Selected Publications

Achinger-Kawecka J, Taberlay PC, Clark SJ. Alterations in Three-Dimensional Organization of the Cancer Genome and Epigenome. Cold Spring Harb Symp Quant Biol. 2017 Apr 19. pii: 031013. doi: 10.1101/sqb.2016.81.031013. [Epub ahead of print]

Achinger-Kawecka J, Clark SJ. Disruption of the 3D cancer genome blueprint. Epigenomics, 2017 9 (1): 47-55 doi:10.2217/epi-2016-0111

Taberlay PC*, Achinger-Kawecka J*, Lun AT, Buske FA, Sabir K, Gould CM, Zotenko E, Bert SA, Giles KA, Bauer DC, Smyth GK, Stirzaker C, O'Donoghue SI, Clark S. Three-dimensional disorganisation of the cancer genome occurs coincident with long range genetic and epigenetic alterations. Genome Research 2016. 26: 719-731 *Equal first authors

Reiner Hoppe*, Joanna Achinger-Kawecka*, Stefan Winter, Peter Fritz, Wing-Yee Lo, Werner Schroth, Hiltrud Brauch. Increased expression of miR-126 and miR-10a predict prolonged relapse-free time of primary oestrogen receptor-positive breast cancer following tamoxifen treatment. European Journal of Cancer, 2013, doi:10.1016/j.ejca.2013.07.145 *Equal first authors

Dr Joanna Achinger-Kawecka



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