Human Comparative and Prostate Cancer Genomics
The team is focused on understanding the complexities of the human and cancer genome and how genomic variation has shaped human evolution and health, cancer evolution, risk and outcomes. The team is using and developing an array of genomic tools from whole genome mapping, whole genome sequencing, exome sequencing, mitochondrial genome sequencing, high-throughput genotyping, Y-chromosome analysis and admixture mapping to capture genomic complexity, while computational and molecular-based methods are used to predict biological impact.
The most complex of the human genomes, specifically the earliest derived (most divergent or genetically distinct) and highly admixed human populations from Southern Africa, and the complex cancer genome of the prostate, form the focus of our laboratory. To address the complex genomics of early-derived human diversity and prostate cancer, the team is actively involved in adopting new state-of-the-art technologies.
In the News
Mapping the genome of prostate cancer uncovers a new world of DNA rearrangements - Apr 11, 2017
2015 St Vincent's Precinct 3 Minute Thesis Competition Held - Jun 19, 2015
Ancient human genome from southern Africa throws light on our origins - Sep 29, 2014
Garvan led team wins prestigious prostate cancer award - Mar 13, 2014
Garvan announces the purchase of Irys Technology from BioNano Genomics - Dec 04, 2013
Genomics expert to assume Petre Foundation Chair of Prostate Cancer Research - Nov 30, 2013
Professor Vanessa Hayes awarded for exceptional Africa-related work - Jul 29, 2013
A finding that could help Alpha-1 sufferers breathe more easily - Dec 14, 2012
Garvan scientist wins Academy of Science Award - Jan 22, 2008
How Garvan Tall Poppy searches for prostate cancer gene - Oct 19, 2007
Genes and disease - Jun 13, 2007