Dr Eva Chan

Dr Eva Chan completed her PhD in Computational Genetics and Genomics at the University of New South Wales, where she studied the genetic influence of gene expression. Following two Bioinformatics postdoctoral positions, at CSIRO (QLD, Australia) and University of California, Davis (CA, USA), Dr Chan
Senior Research Officer/Analyst

Dr Eva Chan completed her PhD in Computational Genetics and Genomics at the University of New South Wales, where she studied the genetic influence of gene expression. Following two Bioinformatics postdoctoral positions, at CSIRO (QLD, Australia) and University of California, Davis (CA, USA), Dr Chan took up a position as the Statistical Genetics Lead at the Vegetable Seeds Division of Monsanto Company, in California, in 2009.

Returning to Sydney in 2013, Dr Chan joined the Garvan Institute of Medical Research, undertaking research in human genomic diversity with particular interest in large-scale structural variations.

Research Interests

Computational genomics
Statistical genetics
Bioinformatics
Phylogenomics

Education

2007 - PhD, University of New South Wales - Australia
2002 - Honours, University of New South Wales - Australia
2001 - BSc, University of Queensland - Australia

Patents

Caldwell D, Chan E, De Vries J, Joobeur T, King J, Reina A, Shetty N. Methods and Compositions for identifying Downy Mildew resistance in cucumber plants. World patent WO/2011/050,296, 28 April 2011; US patent 12,910,478, 22 October 2010 .

Braun CJ III, Chan EKF, Garvey GS, Jones CM, Just BJ, Kniskern JM, Mein JR, Osborn TC, Van Poppel PMJA. Selection of Mature Fruit Color in Pepper Plants. WIPO patent WO/2014/204815, 24 December 2014; US patent 9,723,797, 23 June 2014.

Black L, Chan EKF, Colcol JF, Jones R, Kramer C, Xiang W. Disease resistance loci in Onion. US patent 14,550,705, 21 November 2014.

Selected Publications

Chan EKF, Petersen DC, Lyons RJ, Baldi BF, Papenfuss AT, Thomas DM, Hayes VM. Whole genome optical mapping reveals multiple fusion events chained by large novel sequences in cancer. bioRxiv. doi: 10.1101/166173.

Kalsbeek AMF, Chan EKF, Grogan J, Petersen DC, Jaratlerdsiri W, Gupta R, Lyons RJ, Haynes A, Horvath LG, Kench JG, Stricker PD, Hayes VM. Altered mitochondrial genome content signals worse pathology and prognosis in prostate cancer. The Prostate. 78 (1), 25-31.

Jaratlerdsiri W*, Chan EKF*, Petersen DC*, Yang C, Croucher PI, Bornman MSR, Sheth P, Hayes VM. Next generation mapping reveals novel large genomic rearrangements in prostate cancer. Oncotarget. 8(14): 23588-23602. (* equal first authors)

McCrow JP, Petersen DC, Louw M, Chan EK, Harmeyer K, Vecchiarelli S, Lyons RJ, Bornman MS, Hayes VM. Spectrum of mitochondrial genomic variation and associated clincal presentation of prostate cancer in South African men.  Prostate 2016; 76:349-58

Chan EK, Hardie RA, Petersen DC, Beeson K, Bornman RM, Smith AB, Hayes VM. Revised timeline and distribution of the earliest diverged human maternal lineages in southern Africa. PLoS One 2015; 10:e0121223

Chan EKF, Rowe HC, Corwin JA, Joseph B, Kliebenstein  DJ. Combining genome wide association mapping and transcriptional networks to identify novel genes controlling glucosinolates in Arabidopsis thaliana. PloS Biology. 2011; 9(8):e1001125.

Chan EKF, Rowe HC, Hansen BG, Kliebenstein DJ. The Complex Genetic Architecture of the Metabolome. PLoS Genetics 2010;6(11): e1001198 

Chan EKF, Rowe HC, Kliebenstein DJ. Understanding the evolution of defense metabolites in Arabidopsis thaliana using genome-wide association mapping. Genetics 2010; 185:991-1007.

Chan EKF, Nagaraj SH, Reverter A. The evolution of tropical adaptation: Comparing Taurine and Zebu cattle. Animal Genetics 2010; 41(5):467-477.

Chan EKF and Reverter A. The combined effect of SNP-marker and phenotype attributes in genome wide association studies. Animal Genetics 2009; 40(2):149-156.

Reverter A, Chan EKF. Combining partial correlation and an information theory approach to the reversed-engineering of gene co-expression networks. Bioinformatics 2008; 24(21):2491-2497.

Williams RBH*, Chan EKF*, Cowley MJ, Little PFR. The influence of genetic variation on gene expression. Genome Research 2007; 17:1707-1716. (* equal first authors)

Person portrait

Dr Eva Chan



Collaborative Program

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