Transcriptomic Research Lab

Selected Publications

Clark MB*, Mercer TR*, Bussotti G, Leonardi T, Haynes KR, Crawford J, Brunck ME, Cao KA, Thomas GP, Chen WY, Taft RJ, Nielsen LK, Enright AJ, Mattick JS, Dinger ME. (2015) Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing. Nature Methods. 2015 Apr;12(4):339-42. 

Mercer TR*, Clark MB*, Andersen SB, Brunck ME, Haerty W, Crawford J, Taft RJ, Nielsen LK, Dinger ME, Mattick JS. (2015) Genome-wide discovery of human splicing branchpoints. Genome Research Feb;25(2):290-303. 

Mercer TR*, Clark MB*, Crawford JE, Brunck ME, Taft RJ, Nielsen LK, Dinger ME and Mattick JS. (2014) Targeted RNA sequencing for gene discovery and quantification. Nature Protocols. May;9(5):989-1009.

Mercer TR, Edwards SL, Clark MB, Neph SJ, Wang H, Stergachis AB, John S, Sandstrom R, Li G, Sandhu KS, Ruan Y, Nielsen LK, Mattick JS and Stamatoyannopoulos JA. (2013) DNase I–hypersensitive exons colocalize with promoters and distal regulatory elements. Nature Genetics  45: 852-9.

Mercer TR, Mattick JS. (2013) Understanding the regulatory and transcriptional complexity of the genome through structure. Genome Research. 23: 1081-1088

Mercer TR, Mattick JS (2012) Structure and function of long noncoding RNAs in epigenetic regulation. Nature Structural and Molecular Biology. 20: 300-307

Mercer TR, Gerhardt DJ, Dinger ME, Crawford J, Trapnell C, Jeddeloh JA, Mattick JS, Rinn JL (2011) Targeted RNA sequencing reveals deep complexity of the human transcriptome. Nature Biotechnology 30: 99-104

Mercer TR, Neph S, Dinger ME, Crawford J, Smith MA, Shearwood AJ, Haugen E, Bracken CP, Stamatoyannopoulos JA, Filipovska A, Mattick JS (2011) The human mitochondrial transcriptome. Cell 146: 645-658.

Mercer TR*, Dinger ME*, Bracken CP, Kolle G, Szubert JM, Korbie DJ, Askarian-Amiri ME, Gardiner BB, Goodall GJ, Grimmond SM, Mattick JS (2010) Regulated post-transcriptional RNA cleavage diversifies the eukaryotic transcriptome. Genome Research 20: 1639-1650.

Mercer TR, Dinger ME, Mattick JS (2009). Long noncoding RNA: insights into function. Nat Genet Rev. 10: 155-159.

Mercer TR*, Dinger ME*, Sunkin SM, Mehler MF, Mattick JS (2008). Specific expression of noncoding RNAs in the adult mouse brain. P. Natl. Acad. Sci. USA. 105: 716-721.


More Garvan Publications