Clinical Diabetes, Appetite and Metabolism Lab

Selected Publications

Clarke J, Proudfoot J, Vatiliotis V, Verge C, Holmes-Walker DJ, Campbell L, Wilhelm K, Moravac C, Indu PS, Bridgett M.  Attitudes towards mental health, mental health research and digital interventions by young adults with type 1 diabetes: A qualitative analysis.  Health Expect. 2018 doi: 10.1111/hex.12662. [Epub ahead of print]

Kozan P, Blythe JC, Greenfield JR, Samocha-Bonet D. The Effect of Buffering High Acid Load Meal with Sodium Bicarbonate on Postprandial Glucose Metabolism in Humans-A Randomized Placebo-Controlled Study. Nutrients. 2017 9(8). pii: E861.

Isaacs M1, Tonks KT1,2,3, Greenfield JR1,2,3. Euglycaemic diabetic ketoacidosis in patients using sodium-glucose co-transporter 2 inhibitors. Intern Med J. 2017 47(6):701-704.

Lee P, Swarbrick MM, Greenfield JR.   The Sum of All Browning in FGF21 Therapeutics.  Cell Metab. 2015 21:795-6.

Lee P and Greenfield JR. Non-pharmacological and pharmacological strategies of brown adipose tissue recruitment in humans. Molecular and Cellular Endocrinology. 2015 Dec 15;418 Pt 2:184-90. Review.

Samocha-Bonet D, Chisholm DJ, Gribble FM, Holst JJ, Greenfield JR. L-glutamine and whole protein restore first-phase insulin response and increase glucagon-like peptide-1 in type 2 diabetes patients. Nutrients. 2015 Mar 24;7 (4):2101-8.

Lee P, Greenfield JR. What is the optimal bone-preserving strategy for patients with Addison’s disease? Clin Endocrinol (Oxf). 2015 Aug 83(2):157-61.

Kozusko K, Tsang VHM, Bottomley W, Cho YH, Gandotra S, Mimmack ML, Lim K, Isaac I, Patel S, Saudek V, O'Rahilly S, Srinivasan S, Greenfield JR, Barroso I, Campbell LV, DB Savage. Clinical and molecular characterization of a novel PLIN1 frameshift mutation identified in patients with familial partial lipodystrophy. Diabetes. 2015 64: 299-310.

Samocha-Bonet D, Chisholm DJ, Gribble FM, Coster AC, Carpenter KH, Jones GR, Holst JJ, Greenfield JR. Glycemic Effects and Safety of L-Glutamine supplementation with or without sitagliptin in type 2 diabetes patients-a randomized study. PLoS One. 2014 20: e113366.

Kozusko K, Tsang VHM, Bottomley W, Cho YH, Gandotra S, Mimmack ML, Lim K, Isaac I, Patel S, Saudek V, O'Rahilly S, Srinivasan S, Greenfield JR, Barroso I, Campbell LV, DB Savage. Clinical and molecular characterization of a novel PLIN1 frameshift mutation identified in patients with familial partial lipodystrophy. Diabetes. 2014.

Heilbronn LK, Campbell LV, Xu, A, Samocha Bonet D. Metabolically protective cytokines adiponectin and fibroblast growth factor-21 are increased in acute overfeeding in healthy humans. PLOS-One 2013; 8:e78864.

Jenkins A, Batterham M, Samocha-Bonet D, Tonks K, Greenfield JR, Campbell LV. Segregation of a latent high adiposity phenotype in families with a history of type 2 diabetes mellitus implicates rare obesity-susceptibility genetic variants with large effects in diabetes-related obesity. PLOS One 2013; 8:e70435.

Samocha-Bonet D, Heilbronn LK, Lichtenberg D, Campbell LV. Does skeletal muscle oxidative stress initiate insulin resistance in genetically predisposed individuals?  Trends Endocrinol Metab. 2010; 21:83-8.

Peake P, Colagiuri S, Campbell LV and Shen Y. Paradoxically low levels of total and HMW adiponectin in relation to metabolic parameters in a Tongan population. ISRN Endocrinology 2013; 2013:873507.

Singer J, Trollor JN, Crawford J, O'Rourke MF, Baune BT, Brodaty H, Samaras K, Kochan NA, Campbell L, Sachdev PS, Smith E. The Association between Pulse Wave Velocity and Cognitive Function: The Sydney Memory and Ageing Study.  PLoS One. 2013; 8:e61855.

Greenfield JR, Chisholm DJ. How sweet it is: intestinal sweet taste receptors in type 2 diabetes. Diabetes 2013; 62:3336-3337.

Hocking SL, Samocha-Bonet D, Milner K-L, Greenfield JR, Chisholm DJ. Adiposity and insulin resistance in humans: the role of the different tissue and cellular lipid depots. Endocr Rev 2013; 34: 463-500.

Chang J, Wu T, Greenfield JR, Samocha-Bonet D, Horowitz M, Rayner CK. Effects of intraduodenal glutamine on incretin hormone and insulin release, the glycemic response to an intraduodenal glucose infusion and antropyloroduodenal motility in health and type 2 diabetes. Diabetes Care 2013; 36: 2262-2265.

Tonks KT, Ng Y, Miller S,Coster ACF, Samocha-Bonet D, Iseli TJ, Xu A, Patrick P, Yang JYH, Junutula JR, Modrusan Z, Kolumam G, Stöckli J, Chisholm DJ, James DE*,Greenfield JR* (*equal last authors).Impaired Akt phosphorylation in insulin-resistant human muscle is accompanied by selective and heterogeneous downstream defects. Diabetologia. 2013; 56: 875-85.

Greenfield JR, Samaras K, Campbell LV. Sugar-Sweetened Beverages and Genetic Risk of Obesity (Letter).  N Engl J Med. 2013; 368:285.

Purtell L, Jenkins A, Viardot A, Herzog H, Sainsbury A, Smith A, Loughnan G, Steinbeck K, Campbell LV, Sze L. Postprandial cardiac autonomic function in Prader-Willi syndrome.  Clin Endocrinol (Oxf). 2013; 79(1):128-33.

Samocha-Bonet D, Campbell LV, Mori TA, Croft KD, Greenfield JR, Turner N, Heilbronn LK.  Overfeeding reduces insulin sensitivity and increases oxidative stress, without altering markers of mitochondrial content and function in humans.  PLoS One. 2012; 7(5) e36320.

Samocha-Bonet D, Chisholm DJ, Tonks K, Campbell LV, Greenfield JR. Insulin-sensitive obesity in humans - a 'favorable fat' phenotype? Trends Endocrinol Metab. 2012; 23:116-24.

Trollor JN, Smith E, Agars E, Kuan SA, Baune BT, Campbell LV, Samaras K, Crawford J, Lux O, Kochan NA, Brodaty H, Sachdev P. The association between systemic inflammation and cognitive performance in the elderly: The Sydney Memory and Ageing Study. Age (Dordr). 2012; 34:1295-308.

Wilhelm K, Gillis I, Reddy J, Mitchell PB, Campbell L, Dobson-Stone C, Pierce KD, Schofield PR. Association between serotonin transporter promoter polymorphisms and psychological distress in a diabetic population. Psychiatry Res.  2012; 200:343-8.

Purtell L, Sze L, Loughnan G, Smith E, Herzog H, Sainsbury A, Steinbeck K, Campbell LV, Viardot A. In adults with Prader-Willi syndrome, elevated ghrelin levels are more consistent with hyperphagia than high PYY and GLP-1 levels. Neuropeptides. 2011; 45:301-7.

Ho-Pham LT, Campbell LV, Nguyen TV. More on body fat cutoff points. Mayo Clin Proc. 2011; 86:584.

Sze L, Purtell L, Jenkins A, Loughnan G, Smith E, Herzog H, Sainsbury A, Steinbeck K, Campbell LV, Viardot A. Effects of a Single Dose of Exenatide on Appetite, Gut Hormones, and Glucose Homeostasis in Adults with Prader-Willi Syndrome. J Clin Endocrinol Metab. 2011; 96:E1314-9.

Smith EV, Hay P, Campbell LV and Trollor JN. A review of the association between obesity and cognitive function across the lifespan: implications for novel approaches to prevention and treatment. Obesity Reviews 2011; 12:740-755.

Samocha-Bonet D, Wong O, Synnott, E-S, Piyaratna N, Douglas A, Gribble FM, Holst JJ, Chisholm DJ, Greenfield JR. Glutamine reduces postprandial glycaemia and augments the GLP-1 response in type 2 diabetes patients. J Nutrition 2011; 141: 1233-1238.

Martinelli CE, Keogh JM, Greenfield JR, Henning E, van der Klaauw AA, Blackwood A, O'Rahilly S, Roelfsema F, Camacho-Hubner C, Pijl H, Farooqi IS. Obesity due to Melanocortin 4 Receptor (MC4R) deficiency is associated with increased linear growth and final height, fasting hyperinsulinemia, and incompletely suppressed Growth Hormone secretion. J Clin Endocrinol Metab 2011; 96:E181-188E.

Greenfield JR. Invited review (Young Investigator Perspectives): Melanocortin signalling and the regulation of blood pressure in human obesity. Journal of Neuroendocrinology 2011; 23:186-193.

Campbell LV, Heitmann B. Gender bias in management of cardiovascular disease in women. Cardiology in General Practice.  2010; 14:30-31.

Viardot A, Sze L, Purtell L, Sainsbury A, Loughnan G, Smith E, Herzog H, Steinbeck K, Campbell LV. Prader-Willi Syndrome is associated with activation of the innate immune system independently of central adiposity and insulin resistance. J Clin Endocrinol Metab. 2010; 95:3392-9.

Tam CS, Viardot A, Clément K, Tordjman J, Tonks K, Greenfield JR, Campbell LV, Samocha-Bonet D, Heilbronn LK. Short-term overfeeding may induce peripheral insulin resistance without altering subcutaneous adipose tissue macrophages in humans.  Diabetes. 2010; 59:2164-70.

Jenkins AB, Campbell LV. Insulin secretion and impaired glucose tolerance. Diabetologia. 2010; 53:2266-8.

Ta MT, Nguyen KT, Nguyen ND, Campbell LV, Nguyen TV. Identification of undiagnosed type 2 diabetes by systolic blood pressure and waist-to-hip ratio. Diabetologia 2010; 53:2139-46.

Samocha-Bonet D, Campbell LV, Viardot A, Freund J, Tam CS, Greenfield JG, Heilbronn LK. A family history of type 2 diabetes increases risk factors associated with overfeeding. Diabetologia. 2010; 53:1700-8.

More Garvan Publications