Insulin Signalling Lab

Selected Publications

Schmitz-Peiffer C.  Anarchy in the UPR: A Ca2+-insensitive PKC inhibits SERCA activity to promote ER stress.  Biosci Rep. 2018 pii: BSR20170966. doi: 10.1042/BSR20170966. [Epub ahead of print].

Chandrashekaran IR, Norton RS, Schmitz-Peiffer C.  Characterisation of peptide interactions that regulate PKCε activation.  FEBS Lett. 2018; 592(2):179-189.

M.K. Montgomery, S.H. Brown, X.Y. Lim, C.E. Fiveash, B. Osborne, N.L. Bentley, J.P Braude, T.W. Mitchell, A.C. Coster, A.S. Don, G.J Cooney, C. Schmitz-Peiffer, N. Turner. Regulation of Glucose Homeostasis and Insulin Action by Ceramide Acyl-Chain Length: A Beneficial Role for Very Long-Chain Sphingolipid Species. Biochim. Biophys. Acta 2016; 1861:1828-1839.

B. Hayward,  J. C. Molero, K. Windmill, A. Sanigorski, J. Weir, N. L. McRae, K. Aston-Mourney, B. Osborne, B. Liao, K. R. Walder, P.J. Meikle, N. Konstantopoulos, C. Schmitz-Peiffer.  Pathways of Acetyl-CoA Metabolism Involved in the Reversal of Palmitate-Induced Glucose Production by Metformin and Salicylate.   Experimental and Clinical Endocrinology & Diabetes. 2016. In Press.

B. M. Liao, S. A. McManus, W. E. Hughes,  C. Schmitz-Peiffer.  Flavin-Containing Monooxygenase 3 Reduces Endoplasmic Reticulum Stress in Lipid-Treated Hepatocytes.  Mol Endocrinol. 2016 30(4):417-28.

B. M. Liao, K. Raddatz, L. Zhong, B. L. Parker, M. J. Raftery, C. Schmitz-Peiffer.  Proteomic Analysis of Livers from Fat-fed Mice Deficient in Either PKC delta or PKC epsilon Identifies Htatip2 as a Regulator of Lipid Metabolism.  Proteomics 2014 14:2578-87.

C. Schmitz-Peiffer. The Tail Wagging the Dog - Regulation of Lipid Metabolism by Protein Kinase C. Febs J. 2013; 280:5371-83.

D. J. Pedersen, B. Diakanastasis, J. Stoeckli and C. Schmitz-Peiffer. Protein Kinase Cepsilon Modulates Insulin Receptor Localization and Trafficking in Mouse Embryonic Fibroblasts. PLoS ONE 2013; 8: e58046.

G. Frangioudakis, B. Diakanastasis, B. Q. Liao, J. T. Saville, N. J. Hoffman, T. W. Mitchell and C. Schmitz-Peiffer. Ceramide Accumulation in L6 Skeletal Muscle Cells Due to Increased Activity of Ceramide Synthase Isoforms Has Opposing Effects on Insulin Action to Those Caused by Palmitate Treatment. Diabetologia 2013; 56:2697-701.


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