B Cell Biology Lab

Publications

Regulation of B-Cell Self-Tolerance By BAFF and the Molecular Basis of Its Action
Gardam, S.; Brink, R.
Contemporary Immunology:BLys Ligands and Receptors X111:43-63, 2010
Regulation of B cell self-tolerance by BAFF
Brink, R. :
SEMINARS IN IMMUNOLOGY 18(5):276-83, 2006
MicroRNA-155 controls affinity-based selection by protecting c-MYC+ B cells from apoptosis.
Nakagawa, R.; Leyland, R.; Meyer-Hermann, M.; Lu, D.; Turner, M.; Arbore, G.; Phan, TG.; Brink, R.; Vigorito, E.
JOURNAL OF CLINICAL INVESTIGATION 126:377-88, 2016
In vivo photolabeling of tumor-infiltrating cells reveals highly regulated egress of T-cell subsets from tumors.
Torcellan, T.; Hampton, HR.; Bailey, J.; Tomura, M.; Brink, R.; Chtanova, T.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 144(22):5677-5682, 2017
Plasma cell and memory B cell differentiation from the germinal center.
Suan, D.; Sundling, C.; Brink, R.
CURRENT OPINION IN IMMUNOLOGY 45:97-102, 2017
Control systems and decision making for antibody production
Goodnow, C.C; Vinuesa, C.G; Randall, K.L.; Mackay, F.; Brink, R.
NATURE IMMUNOLOGY 11(8):681-8, 2010
An open letter to the Prime Minister, the Honourable Tony Abbott, MP The G20, human health and sustainability: an interview with Jeffrey D Sachs
McMichael, A. J.; Leeder, S. R.; Armstrong, B. K.; Basten, A.; Doherty, P. C.; Douglas, R. M.; Green, A. C.; Nossal, G. J.; Shearman, D. J.; Stanley, F. J.; Vimpani, G. V.; Wodak, A. D.;
MEDICAL JOURNAL OF AUSTRALIA 2014
Lineage-specific transgene expression in hematopoietic cells using a versatile Cre-regulated retroviral vector
Turner, V.M; Gardam, S.; Brink, R.
JOURNAL OF IMMUNOLOGICAL METHODS 360(1-2):162-166, 2010
The role of B cells in transplantation and immunopathic diseases
Basten, A.;
Immune Network 10(3):81-4, 2010
SAMHD1 enhances immunoglobulin hypermutation by promoting transversion mutation
Thientosapol, E. S.; Bosnjak, D.; Durack, T.; Stevanovski, I.; van Geldermalsen, M.; Holst, J.; Jahan, Z.; Shepard, C.; Weninger, W.; Kim, B.; Brink, R.; Jolly, C. J.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 115(19):4921-4926, 2018
Self-Reactive B Cells in the Germinal Center Reaction
Brink, R.; Phan, T. G.
Annual Review of Immunology 36:339-357, 2018
The imperfect control of self-reactive germinal center B cells
Brink, R.
CURRENT OPINION IN IMMUNOLOGY 28:97-101, 2014
LOX-1 unlocks human plasma cell potential
Brink, R.
IMMUNITY 41(4):507-8, 2014
B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling
Mackay, F.;Silveira, P. A.;Brink, R. :
CURRENT OPINION IN IMMUNOLOGY 19(3):327-36, 2007
Germinal-center B cells in the zone
Brink, R. :
IMMUNITY 26(5):552-4, 2007
FAS inactivation releases "Rogue" Germinal Center B cells that escape antigen control and drive IgE and autoantibody production
Butt D, Chan TD, Bourne K, Hermes JR, Nguyen A, O'Reilly L, Strasser A, Schofield P, Christ D,; Basten A, Ma C, Tangye S, Phan TG, Rao VK and Brink R
IMMUNITY 42(5):890-902, 2015
Chronic bacterial infection activates autoreactive B cells and induces isotype switching and autoantigen-driven mutations
Jung, S.; Schickel, J.; Kern, A.; Knapp, AM.; Eftekhari, P.; Da Silva, S.; Jaulhac, B.; Brink, R.; Soulas-Sprauel P.; Pasquali, JL.; Martin, T.; Korganow, AS.
EUROPEAN JOURNAL OF IMMUNOLOGY 46:131-146, 2016
Atypical chemokine receptor 4 shapes activated B cell fate
Kara, E. E.; Bastow, C. R.; McKenzie, D. R.; Gregor, C. E.; Fenix, K. A.; Babb, R.; Norton, T. S.; Zotos, D.; Rodda, L. B.; Hermes, J. R.; Bourne, K.; Gilchrist, D. S.; Nibbs, R. J.; Alsharifi, M.; Vinuesa, C. G.; Tarlinton, D. M.; Brink, R.; Hill, G. R.; Cyster, J. G.; Comerford, I.; McColl, S. R.
JOURNAL OF EXPERIMENTAL MEDICINE 215(3):801-813, 2018
TRAF3 regulates the effector function of regulatory T cells and humoral immune responses
Chang, J. H. ; Hu, H. %A Jin, J. ; Puebla-Osorio, N. ; Xiao, Y. ; Gilbert, B. E. ; Brink, R. ; Ullrich, S. E. Sun, S. C.;
J EXP MED 211(1):137-51, 2014
In vivo control of B cell survival and antigen-specific B cell responses
Chan, T. D.; Gardam, S.; Gatto, D.; Turner, V. M.; Silke, J.; Brink, R.:
IMMUNOLOGICAL REVIEWS 237(1):90-103, 2010
Elimination of germinal center-derived self-reactive B cells is governed by the location and level of self-antigen
Chan, T.D.; Wood, K.; Hermes, J.R.; Butt, D.; Jolly, C.J.; Basten, A.; Brink, R.
IMMUNITY 37(5):893-904, 2012
New friends for bone marrow plasma cells
Brink, R.
NATURE IMMUNOLOGY 12(2):115-7, 2011
Deletion of cIAP1 and cIAP2 in murine B lymphocytes constitutively activates cell survival pathways and inactivates the germinal center response
Gardam, S.; Turner, V.M.; Anderton, H.; Limaye, S.; Basten, A.; Koentgen, F.; Vaux, D.L.; Silke, J.; Brink, R.
Blood 117(15):4041-51, 2011
EBI2 unlocks the door to the Tfh cell nursery
Brink, R.;
IMMUNOLOGY AND CELL BIOLOGY 94(7):621-2, 2016
Redemption of autoantibodies on anergic B cells by V-region glycosylation and mutation away from self-reactivity
Sabouri Z, Schofield PR, Horikawa K, Spierings E, Kipling E, Randall K, Langley D, Roome B, Vazquez-Lombardi R, Rouet R, Hermes J, Chan T, Brink R, Dunn-Walters DK, Christ D and Goodnow CC
P NATL ACAD SCI USA 2014
CCR6 defines memory B cell precursors in mouse and human germinal centers revealing light zone location and predominant low antigen affinity.
Suan, D.; Krautler, N.J.; Maag, J.L.V.; Butt, D.; Bourne, K.; Hermes, J.R.; Avery, D.T.; Young, C.; Statham, A.; Elliott, M.; Dinger, M.E.; Basten, A.; Tangye, S.G.; Brink, R.
IMMUNITY 47(6):1142-1153, 2017