Cellular Immunity

The lab is focussed on four main topics on T cell biology:

  • transplantation tolerance by using particular IL-2/mAb complexes to induce selective expansion of T regulatory cells,
  • defining the mechanisms controlling self tolerance and homeostasis when naïve T cells differentiate into memory cells,
  • tolerance to the foetus during pregnancy, and
  • cancer immunotherapy induced by injection of antigen-loaded membrane fragments from antigen-presenting cells.

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