The lab is focussed on four main topics on T cell biology:
- transplantation tolerance by using particular IL-2/mAb complexes to induce selective expansion of T regulatory cells,
- defining the mechanisms controlling self tolerance and homeostasis when naïve T cells differentiate into memory cells,
- tolerance to the foetus during pregnancy, and
- cancer immunotherapy induced by injection of antigen-loaded membrane fragments from antigen-presenting cells.