Lymphocyte Signalling and Activation Lab

Publications

The circulating life of a memory T-follicular helper cell
Ma, C. S.; Deenick, E. K.
Clinical & Translational Immunology 6(5):e145, 2017
Reversible Suppression of Lymphoproliferation and Thrombocytopenia with Rapamycin in a Patient with Common Variable Immunodeficiency
Deenick, E. K.; Morey, A.; Danta, M.; Emmett, L.; Fay, K.; Gracie, G.; Ma, C. S.; Macintosh, R.; Smith, Sabc; Sasson, S. C.; Sewell, W. A.; Cowley, M.; Tangye, S. G.; Kelleher, A. D.; Circa; Phan, T. G.
JOURNAL OF CLINICAL IMMUNOLOGY 38(2):159-162, 2018
IMMUNODEFICIENCIES. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations
Okada, S.; Markle, J. G.; Deenick, E. K.; Mele, F.; Averbuch, D.; Lagos, M.; Alzahrani, M.; Al-Muhsen, S.; Halwani, R.; Ma, C. S.; Wong, N.; Soudais, C.; Henderson, L. A.; Marzouqa, H.; Shamma, J.; Gonzalez, M.; Martinez-Barricarte, R.; Okada, C.; Avery, D. T.; Latorre, D.; Deswarte, C.; Jabot-Hanin, F.; Torrado, E.; Fountain, J.; Belkadi, A.; Itan, Y.; Boisson, B.; Migaud, M.; Arlehamn, C. S.; Sette, A.; Breton, S.; McCluskey, J.; Rossjohn, J.; de Villartay, J. P.; Moshous, D.; Hambleton, S.; Latour, S.; Arkwright, P. D.; Picard, C.; Lantz, O.; Engelhard, D.; Kobayashi, M.; Abel, L.; Cooper, A. M.; Notarangelo, L. D.; Boisson-Dupuis, S.; Puel, A.; Sallusto, F.; Bustamante, J.; Tangye, S. G.; Casanova, J. L.;
SCIENCE 349(6248):606-13, 2015
Molecular and cellular mechanisms underlying defective antibody responses.
Deenick, E.K.; Lau, A.; Bier, J.; Kane, A.
IMMUNOLOGY AND CELL BIOLOGY 98(6):467-479, 2020
Immune Dysregulation and Disease Pathogenesis due to Activating Mutations in PIK3CD-the Goldilocks' Effect
Tangye, S. G.; Bier, J.; Lau, A.; Nguyen, T.; Uzel, G.; Deenick, E. K.
JOURNAL OF CLINICAL IMMUNOLOGY 39(2):148-158, 2019
The regulation and role of T follicular helper cells in immunity
Deenick, E. K.; Ma, C. S.
IMMUNOLOGY 134(4):361-7, 2011
B cells: we need them now more than ever.
Deenick, E.K
IMMUNOLOGY AND CELL BIOLOGY 98(6):437-438, 2020
NK Cells Regulate CD8(+) T Cell Mediated Autoimmunity
Lang, P. A.; Crome, S. Q.; Xu, H. C.; Lang, K. S.; Chapatte, L.; Deenick, E. K.; Grusdat, M.; Pandyra, A. A.; Pozdeev, V. I.; Wang, R.; Holderried, T. A. W.; Cantor, H.; Diefenbach, A.; Elford, A. R.; McIlwain, D. R.; Recher, M.; Haussinger, D.; Mak, T. W.; Ohashi, P. S.
Frontiers in Cellular and Infection Microbiology 10:36, 2020
Activated PI3Kdelta breaches multiple B cell tolerance checkpoints and causes autoantibody production
Lau, A.; Avery, D. T.; Jackson, K.; Lenthall, H.; Volpi, S.; Brigden, H.; Russell, A. J.; Bier, J.; Reed, J. H.; Smart, J. M.; Cole, T.; Choo, S.; Gray, P. E.; Berglund, L. J.; Hsu, P.; Wong, M.; O'Sullivan, M.; Boztug, K.; Meyts, I.; Uzel, G.; Notarangelo, L. D.; Brink, R.; Goodnow, C. C.; Tangye, S. G.; Deenick, E. K.
JOURNAL OF EXPERIMENTAL MEDICINE 217(2):e20191336, 2020
Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4(+) T cells
Bier, J.; Rao, G.; Payne, K.; Brigden, H.; French, E.; Pelham, S. J.; Lau, A.; Lenthall, H.; Edwards, E. S. J.; Smart, J. M.; Cole, T. S.; Choo, S.; Joshi, A. Y.; Abraham, R. S.; O'Sullivan, M.; Boztug, K.; Meyts, I.; Gray, P. E.; Berglund, L. J.; Hsu, P.; Wong, M.; Holland, S. M.; Notarangelo, L. D.; Uzel, G.; Ma, C. S.; Brink, R.; Tangye, S. G.; Deenick, E. K.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 144(1):236-253, 2019