DNA, chromosomes and cells

The cells in your body contain DNA, packaged tightly within chromosomes. 


What is your genome?

Your genome is your complete set of genetic information, including all of your DNA.


Introduction to your genome

In this video, learn about your genome and the effects that variants in your DNA can have on your body.


DNA and your health

In this video, learn more about variants and the types of information you can gain from having your genome sequenced.


DNA and medications: Pharmacogenomics

In this video, learn about how your DNA can affect your response to medications like codeine.


Genomic testing

Watch how sequencing, bioinformatics and analysis come together in the genomic testing process.


What is genetic counselling? 

Find out why talking to genetic health professionals is so important, and what to expect in a typical genetic counselling session.


Running a genomics facility

Find out about the huge amounts of infrastructure required to run a genomics facility. 


Security of genomic data

Genomic testing generates a huge amount of data on a person that needs to be stored and transferred securely.  


Weighing up evidence in genomic testing

Critically assessing the scientific evidence base is a crucial step in determining which variants may be contributing to a patient's condition.


A 360 degree view of your genome

Explore your genome in 3D with this 360 degree video designed for Google Cardboard. 


Copying, transferring and translating DNA 

Your cells copy, transfer and translate the information in your DNA to keep your body functioning. 


Transcription close up

Transcription is the first step in the process of decoding the information contained in a gene.


DNA methylation

DNA methylation is one of the ways cells can control which genes are active, and at what time. 


Sequencing a genome

Genome sequencing is a way of analysing a person’s complete set of DNA that can see if they might have, or be at increased risk of, certain diseases.


Genetic variants and disease

Differences in your DNA sequence contribute to your individuality, but can also cause diseases such as inherited heart conditions.


Types of DNA variant: small variants

Variants in your DNA can be large or small, and can affect genes and proteins in different ways. 


Types of DNA variant: structural variation

Rearrangements of large sections of DNA are known as structural variants, and can have a big impact on your health. 


Effects of a genetic variant

Why is it that the same genetic variant can have different effects for different people? 


The impact of genome sequencing

Genome sequencing is being used in medicine to diagnose inherited diseases, target cancer treatments, and identify health risks. 


Filtering and analysing genomic variants

Genomic sequencing data needs to be processed through a series of manual and automated steps.


The genomic research pathway

Genomics research disrupts the traditional research pathway and blurs research and clinical boundaries.


The genome sequencing journey

Sequencing a genome involves a multidisciplinary team of scientists, clinicians, and genetics specialists


A genetic cause of autoimmune disease

Variants in the LRBA gene can have a devastating effect on our immune system, potentially leading to autoimmune disease


Genome editing with CRISPR-Cas9

CRISPR-Cas9 has been adapted for use as a cut-and-paste tool to edit DNA in the laboratory.