Collection

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DNA, chromosomes and cells

The cells in your body contain DNA, packaged tightly within chromosomes. 

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What is your genome?

Your genome is your complete set of genetic information, including all of your DNA.

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Introduction to your genome

In this video, learn about your genome and the effects that variants in your DNA can have on your body.

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DNA and your health

In this video, learn more about variants and the types of information you can gain from having your genome sequenced.

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DNA and medications: Pharmacogenomics

In this video, learn about how your DNA can affect your response to medications like codeine.

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Genomic testing

Watch how sequencing, bioinformatics and analysis come together in the genomic testing process.

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What is genetic counselling? 

Find out why talking to genetic health professionals is so important, and what to expect in a typical genetic counselling session.

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Running a genomics facility

Find out about the huge amounts of infrastructure required to run a genomics facility. 

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Security of genomic data

Genomic testing generates a huge amount of data on a person that needs to be stored and transferred securely.  

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Weighing up evidence in genomic testing

Critically assessing the scientific evidence base is a crucial step in determining which variants may be contributing to a patient's condition.

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A 360 degree view of your genome

Explore your genome in 3D with this 360 degree video designed for Google Cardboard. 

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Copying, transferring and translating DNA 

Your cells copy, transfer and translate the information in your DNA to keep your body functioning. 

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Transcription close up

Transcription is the first step in the process of decoding the information contained in a gene.

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DNA methylation

DNA methylation is one of the ways cells can control which genes are active, and at what time. 

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Sequencing a genome

Genome sequencing is a way of analysing a person’s complete set of DNA that can see if they might have, or be at increased risk of, certain diseases.

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Genetic variants and disease

Differences in your DNA sequence contribute to your individuality, but can also cause diseases such as inherited heart conditions.

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Types of DNA variant: small variants

Variants in your DNA can be large or small, and can affect genes and proteins in different ways. 

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Types of DNA variant: structural variation

Rearrangements of large sections of DNA are known as structural variants, and can have a big impact on your health. 

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Effects of a genetic variant

Why is it that the same genetic variant can have different effects for different people? 

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The impact of genome sequencing

Genome sequencing is being used in medicine to diagnose inherited diseases, target cancer treatments, and identify health risks. 

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Filtering and analysing genomic variants

Genomic sequencing data needs to be processed through a series of manual and automated steps.

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The genomic research pathway

Genomics research disrupts the traditional research pathway and blurs research and clinical boundaries.

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The genome sequencing journey

Sequencing a genome involves a multidisciplinary team of scientists, clinicians, and genetics specialists

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A genetic cause of autoimmune disease

Variants in the LRBA gene can have a devastating effect on our immune system, potentially leading to autoimmune disease

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Genome editing with CRISPR-Cas9

CRISPR-Cas9 has been adapted for use as a cut-and-paste tool to edit DNA in the laboratory.