“Systems thinking” is considered an important skill for genetics and cell biology. Many students struggle to connect biological concepts across molecular, organism and population levels.
This activity models the use of a systems matrix for researching and conceptualising genetic disease. Use of the matrix is taught through three scaffolded case studies. In the third activity, students select a genetic disease and research its cause and effects, beginning with some suggested links and then undertaking independent research to complete the systems matrix. Skills relating to in-text referencing are also introduced. This activity can form the initial stages of a depth study into a genetic disease or be used alone to build understanding of genetic disease, systems thinking and research skills.
The activity also includes a Genetic Disease Resource Guide, which outlines a selection of genetic diseases along with links for students to use as a starting point for independent research (for case study 3 and/or other research tasks).
A full teacher guide is available for this activity. It includes an exemplar of the matrix based on Sickle Cell Disease. Teachers can email email@example.com from a school email address to gain access.
If you are interested in trialling this resource in your classroom and providing feedback, please email firstname.lastname@example.org
HSC Biology NSW
- model the process of polypeptide synthesis, including:
- analysing the function and importance of polypeptide synthesis
- assessing how genes and environment affect phenotypic expression
- investigate the structure and function of proteins in living things
- collect, record and present data to represent frequencies of characteristics in a population, in order to identify trends, patterns, relationships and limitations in data
- compare the causes, processes and effects of different types of mutation
Causes and Responses of Non-infectious Diseases
- investigate the causes and effects of non-infectious diseases in humans, including but not limited to:
- genetic diseases
- investigate the treatment/management, and possible future directions for further research, of a non-infectious disease using an example from one of the non-infectious diseases categories listed above
Processing Data and Information
Analysing Data and Information
DNA and polypeptide synthesis
Types of mutation
Mendelian inheritance (dominant/recessive, carriers etc)
|Research Matrix Activity Guide (Word file)||May 05, 2019 09:13 AM|
|Research Matrix Activity Guide (PDF)||May 05, 2019 09:13 AM|
|Genetic Diseases Resource Guide (Word File)||May 08, 2019 02:14 PM|
|Research Matrix PKU case study (PowerPoint presentation)||May 05, 2019 09:13 AM|
|Research Matrix blank (Word file)||May 05, 2019 09:13 AM|