The Kinghorn Centre for Clinical Genomics (KCCG) comprises six program teams that work closely together to tackle major challenges that will advance the translation of genomic information to improve health.
Our research scope is divided into six key programs:
- Translational Genome Informatics:
Expanding the clinical utility of whole-genome sequencing by developing algorithms to annotate pathogenic loci in noncoding regions of the genome, applied to a range of rare monogenic disorders of substantial unmet need.
- Genomic Technologies:
Ensuring that the Garvan Institute is at the cutting edge of the rapidly evolving genomics technology landscape by evaluating new sequencing platforms, developing new methodologies, and translating these applications into clinical and commercial settings.
Organising the world’s genome information and make it universally accessible and useful to authorised users.
Providing comprehensive solutions to enrich the understanding of the associations occurring between diseases, genotype, phenotype and environment via structured knowledge representation and discovery techniques.
- Tumour genomics:
Establishing rapid and cost-effective genomics tests for cancer diagnosis, prognosis, and risk prediction, which include whole-genome somatic cancer testing, focussed capture sequencing, and inherited cancer predisposition screening.
- Education and Communication:
Developing and delivering targeted educational programs and resources for health professionals and diverse communities on the complex and fast-moving field of genomics.
We are already working on projects that integrate the skills and knowledge of team members across all programs to ensure that we are not siloed and make the most of our diverse expertise.
KCCG researchers are part of multiple national and international research collaborations:
- The Sydney Genomics Collaborative
- Australian Genomics Health Alliance
- Global Alliance For Genomics and Health
The impact of clinical genomics is becoming widespread and its importance to diverse disciplines is becoming increasingly recognised. KCCG engages closely with scientists, clinicians and ethicists through visiting appointments. These individuals bring additional expertise to KCCG and provide a mechanism for reciprocal engagement into the broader genomics community.
|Prof Andreas Zankl||Dr Jacqueline Savard||Dr Paul Lacaze||
|Dr Elizabeth (Emma) Palmer||Prof Carolyn Sue||Dr Ryan Davis||Peter Priestley|
|A/Prof Marcel Dinger|