Genomics is one of the fastest-growing areas of medical research and has emerged as a highly promising source of new insights into the genetic cause of disease.
The Sydney Genomics Collaborative program was established with NSW State Government funding in June 2014 to boost genomic research across NSW into inherited diseases and disorders with a genetic component, including cancer.
The Collaborative utilises the Illumina HiSeq X Ten, a high-speed genome sequencing system operated by the Garvan Institute of Medical Research. The Illumina HiSeq X Ten technology enables the study of whole-genome sequences at the scale of large populations.
The program comprises:
- Medical Genome Reference Bank — a resource containing approximately 4,000 whole genome sequences from healthy, aged people to be used for control purposes in disease-specific genomic research.
- NSW Genomics Collaborative Grants — funding for researchers to undertake whole-genome sequencing to improve understanding of the genetic causes of disease.
- Genomic Cancer Medicine Program — a research program dedicated to applying genomics to the understanding, early detection, prevention and management of cancer, led by the Head of Garvan’s Cancer Division and Director of The Kinghorn Cancer Centre, Professor David Thomas.