Cancer Mechanoimmunology Lab

Our research relies heavily on advanced microscopy and the development of image analysis platforms capable of automatically detecting and analysing the kinetics of the cytoskeleton, cell movements and interactions.

We use high-speed imaging to watch how cells move throughout complex three-dimensional environments and how multicellular systems coordinate behaviours .

Key research areas

• Mechanobiology of immune cell-tumour cell interactions
• Single cell and population-wide immune cell migration dynamics
• Advanced imaging and image analysis
• Computational modelling and simulations

Our lab is spearheading the use of complex in vitro and in vivo models for studying the mechanisms that govern the movements and interplay of immune cells, and their cytotoxic interactions with tumour cells. Using a multidisciplinary approach encompassing cell biology, biophysics, immunology, bioimage informatics and advanced light microscopy, our lab aims to unravel fundamental cell-driven processes and develop new methodologies for both basic cell biological research and applied immunotherapeutic solutions.