Deenick Lab

We are interested in understanding these signals and how they can go wrong – leading to immunodeficiency, allergy and autoimmunity (e.g. diseases such as systemic lupus erythematosus and autoimmune cytopenias). To do this, we study both immune cells from patients and mouse models of disease. Our aim is to understand the dysregulated immune signalling that drives these diseases. This will then allow us to find more effective therapies that directly target and stop drivers of each person’s disease, rather than just dampening their symptoms.