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Genomic Cancer Medicine Lab

Our lab studies the germline and somatic genetics of cancers with poor outcomes, especially those affecting young people.

While we tackle all cancers, we focus particularly on sarcomas. Sarcomas are devastating cancers which arise in connective tissues – bone, muscle, fat and cartilage – and often occur in children and young adults.

We have developed some of the world's largest cohorts of patients and families affected by cancer. We use patient-centred approaches to understand why cancers occur, coupled with experimental systems to explore the biological and therapeutic implications of our clinical discoveries. We utilise state-of-the-art genomic technologies and creative clinical interventions, with the goal of improving health outcomes.

Our aim is to use the power of science to benefit patients and their families. Our approach to achieve this includes:

  • a whole-body MRI program for risk modification for individuals who have a high genetic risk, and
  • an innovative precision medicine trial to test new therapies based on genomic biomarkers.

Research team

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