MetMemory study

MetMemory study

An Australian-led research project at the Garvan Institute, funded by the National Health and Medical Research Council, is recruiting volunteers for a 3-year study examining the effects of metformin on cognition, brain anatomy and early signs of dementia.


We’re looking for people who meet the following eligibility criteria:

  • Live in the greater Sydney region;
  • Are over 60 years of age;
  • Are slightly overweight but do not have diabetes;
  • Do not have dementia;
  • Have concerns about changes in memory or thinking;
  • Are not currently taking metformin.

Metformin is a safe medication used to treat diabetes, but also other metabolic/hormonal conditions.

Our aims are to slow loss of memory and other aspects of cognition with ageing, and examine whether metformin affects other aspects of metabolism, inflammation and the ageing process.

Our team is made up of leading Australian and US dementia researchers, including:


Professor Katherine Samaras Professor Richard Day
Professor Perminder Sachdev Professor Peter MacDonald
Professor Henry Brodaty Dr Nicole Kochan
Professor Maria Fiatarone-Singh A/Professor Wei Wen
Professor Jose Luchsinger – Columbia University, New York In concert with representatives from Alzheimer’s Australia.


For more information, contact by telephone or email:


Phone number: (02) 9295-8585


This study is funded by the National Health and Medical Research Council (#1171665)

This study has been approved by the St Vincent’s Hospital Human Research Ethics Committee   

(HREC 2020 / 01652)