Human Comparative and Prostate Cancer Genomics

Selected Publications

Jaratlerdsiri W, Chan EKF, Petersen DC, Yang C, Croucher PI, Bornman MSR, Sheth P, Hayes VM. Next generation mapping reveals novel large genomic rearrangements in prostate cancer. Oncotarget (2017), Apr 4;8(14):23588-23602.

Hayes VM, Bornman MSR. Prostate cancer in Southern Africa: Does Africa hold untapped potential to add value to current understanding of a common disease? Journal of Global Oncology, (2017) DOI: 10.1200/JGO.2016.008862.

Kalsbeek AMF, Chan EKF, Grogan J, Petersen DC, Jaratlerdsiri W, Gupta R, Lyons RJ, Haynes A-M, Horvath LG, Kench JG, Stricker PD, Hayes VM. Mutational load of the mitochondrial genome predicts pathological features and biochemical recurrence in prostate cancer. Aging (2016) 8(11):2702-2712.

McCrow JP, Petersen DC, Louw M, Chan EK, Harmeyer K, Vecchiarelli S, Lyons RJ, Bornman MS, Hayes VM. Spectrum of mitochondrial genomic variation and associated clincal presentation of prostate cancer in South African men. Prostate 2016; 76:349-58

Stuchbery R, Kurganovs NJ, McCoy PJ, Nelson CC, Hayes VM, Corcoran NM, Hovens CM. Target Acquired: Progress and Promise of Targeted Therapeutics in the Treatment of Prostate Cancer. Cur Canncer Drug Targets 2015; 15:394-405

Chan EK, Hardie RA, Petersen DC, Beeson K, Bornman RM, Smith AB, Hayes VM. Revised timeline and distribution of the earliest diverged human maternal lineages in southern Africa. PLoS One 2015; 10:e0121223

Morris AG, Heinze A, Chan EKF, Smith AB, Hayes VM. First Ancient Mitochondrial Human Genome from a Pre-Pastoralist Southern African. Genome Biology & Evolution, (2014) 6(10):2647-53.

Tindall EA, Monare LR, van Zyl S, Petersen DC, Hardie R-A, Segone AM, Venter PA, Bornman MSR, Hayes VM. Clinical presentation of prostate cancer in Black South Africans. The Prostate, (2014) 74(8):880-91.

Pang AWC, MacDonald JR, Yuen RKC, Hayes VM, Scherer SW. Performance of high-throughput sequencing for the discovery of genetic variation across the complete size spectrum. Genes Genomes Genetics (2014), 4:63-65.

Tindall EA, Bornman MSR, van Zyl S, Petersen DC, Segone AM, Monare LR, Venter PA, Hayes VM. Epidemiological and genetic factors contributing to increased prostate cancer risk and aggressive disease in southern Africa. BMC Urology (2013), 13:74.

Petersen DC, Libiger O, Tindall EA, Hardie R-A, Hannick LI, Glashoff RH, Mukerji M, Indian Genome Variation Consortium, Fernandez P, Haacke W, Schork NJ and Hayes VM. Complex patterns of genomic admixture within southern Africa. PLoS Genetics (2013), 9(3):e1003309.

Saunders DN, Tindall EA, Shearer RF, Roberson J, Decker A, Amos Wilson J, Hayes VM. A novel SERPINA1 mutation causing serum Alpha1-Antitrypsin Deficiency. PLoS One (2012), 7(12):e51762.

Tindall EA, Severi G, Hoang HN, Southey MC, English DR, Hopper JL, Giles GG, Australian Prostate Cancer BioResource, Hayes VM. Interleukin-6 promoter variants, prostate cancer risk and survival. Prostate (2012), 72(16):1701-7.

Hayes VM. Indigenous genomics. Science (2011) May 6; 332(6030):639.

Miller W*, Hayes VM*, Ratan A, Petersen DC, Wittekindt NE, Miller J, Walenz B, Knight J, Qi J, Zhao F, Wang Q, Bedoya O, Katiyar N, Tomsho LP, Kasson LM, Hardie R-A, Woodbridge P, Tindall EA, Bertelsen MF, Dixon D, Pyecroft S, Helgen KM, Lesk AM, Pringle TH, Patterson N, Zhang Y, Kreiss A, Woods GM, Jones ME, Schuster SC*. Genetic diversity and population structure of the endangered marsupial Sarcophilus harrisii (Tasmanian devil). Proceedings of National Academy of Science USA (2011) 108(30):12348-53. NOTE: *Co-corresponding author

Hayes VM, Venter PA, Mphahlele J. Helping hand for genomics in Africa. Nature (2011) 476 (7359):152.

Tindall EA, Petersen DC, Nikolaysen S, Miller W, Schuster SC, Hayes VM. Interpretation of custom designed Illumina genotype cluster plots for targeted association studies and next-generation sequence validation. BMC Research Notes (2010) 3(1):39.

Tindall EA, Severi G, Hoang HN, Ma CS, Fernandez P, Southey MC, English DR, Hopper JL, Heyns CF, Tangye SG, Giles GG, Hayes VM. Comprehensive analysis of the cytokine rich 5q31 region suggests a role for IL-4 gene variants in prostate cancer risk. Carcinogenesis (2010), 31(10):1748-54.

Schuster SC, Miller W, Ratan A, Tomsho LP, Giardine B, Kasson LR, Harris RS, Petersen DC, Zhao F, Qi J, Alkan C, Kidd JM, Sun Y, Drautz DI, Bouffard P, Muzny DM, Reid JG, Nazareth LV, Wang Q, Burhans R, Riemer C, Wittekindt NE, Moorjani1 P, Tindall EA, Danko CG, Siang Teo W, Buboltz A, Zhang Z, Ma Q, Oosthuysen A, Steenkamp A, Oostuisen H, Venter P, Gajewski J, Zhang Y, Pugh BF, Makova KD, Nekrutenko A, Mardis ER, Patterson N, Pringle TH, Chiaromonte F, Mullikin JC, Eichler EE, Hardison RC, Gibbs RA, Harkins TT, Hayes VM. Complete Khoisan and Bantu Genomes from Southern Africa. Nature (2010) 463(7283):943-7.

Tindall EA, Hayes VM. Comprehensive sequence analysis of the human IL23A gene defines new variation content and a high rate of evolutionary conservation. DNA Research (2010) 17(2):117-22.

Tindall EA, Hoang HN, Southey MC, English DR, Hopper JL, Giles GG, Severi G, Hayes VM. The 4q27 locus and familial prostate cancer risk. BMC Cancer (2010) 10(1):69.

Patterson N, Petersen DC, van der Ross RE, Sudoyo H, Glashoff RH, Marzuki S, Reich D, Hayes VM. Genetic structure of a unique admixed population: implications for medical research. Human Molecular Genetics (2010) 19:411-419.

Miller W, Wright SJ, Zhang Y, Schuster SC, Hayes VM. Optimization methods for selecting founder individuals for captive breeding or reintroduction of endangered species. Pacific Symposium on Biocomputing (2010) 2010:43-53.

Ratan A, Zhang Y, Hayes VM, Schuster SC, Miller W. Calling SNPs without a reference sequence. BMC bioinformatics (2010) 11(1):130.

Rasiah KK, Gardiner-Garden M, Padilla EJD, Möller G, Kench J, Alles MC, Eggleton SA, Stricker PD, Adamski J, Sutherland RL, Henshall SM, Hayes VM. HSD17B4 overexpression, an independent biomarker of poor patient outcome in prostate cancer. Molecular and Cellular Endocrinology (2009) 301:89-96.

Tindall EA, Petersen DC, Woodbridge P, Schipany K, Hayes VM. Assessing High Resolution Melt Curve Analysis for accurate detection of gene variants in complex DNA fragments. Human Mutation (2009) 30:876-8311.

Severi G, Hayes VM, Southey MC, Hoang HN, Padilla EJD, Morris HA, English DR, Sutherland RL, Hopper JL, Giles GG. The rs743572 common variant in the promoter of CYP17A1 is not associated with prostate cancer risk or circulating hormonal levels. British Journal of Urology International (2008) 101:492-6.

Petersen DC, Severi G, Hoang HN, Padilla EJD, Southey MC, English DR, Hopper JL, Giles GG, Hayes VM. No association between common chemokine and chemokine receptor gene variants and prostate cancer risk. Cancer Epidemiology Biomarkers and Prevention (2008) 36:3615-17.

Tindall EA, Speight G, Petersen DC, Padilla EJD, Hayes VM. Novel PlexorTM SNP Genotyping Technology: Comparisons with TaqManÒ and Homogenous MassEXTENDTM MALDI-TOF Mass Spectrometry. Human Mutation (2007) 28:922-7.

Hayes VM, Severi G, Padilla EJD, Morris HA, Tilley WD, Southey MC, English DR, Sutherland RL, Hopper JL, Boyle P, Giles GG. 5-Alpha reductase type 2 gene variants associations with prostate cancer risk, circulating hormone levels and androgenetic alopecia. International Journal of Cancer (2007) 120:776-780.

Severi GS, Hayes VM, Padilla EJD, English DR, Southey MC, Sutherland RL, Hopper JL, Giles GG. The common variant rs1447295 on chromosome 8q24 and prostate cancer risk: results from an Australian population-based case-control study. Cancer Epidemiology Biomarkers and Prevention (2007) 16:610-612.

Hayes VM, Severi G, Southey MC, Padilla EJD, English DR, Hopper JL, Giles GG, Sutherland RL. Macrophage Inhibitory Cytokine-1 H6D Polymorphism, Prostate Cancer Risk and Survival. Cancer Epidemiology Biomarkers and Prevention (2006) 15:1223-1225.

Severi G, Hayes VM, P Neufing, EJD Padilla, W Tilley, SA Eggleton, H Morris, DR English, MC Southey, JL Hopper, RL Sutherland, P Boyle, GG Giles. Variants in the prostate-specific antigen (PSA) gene and prostate cancer risk, survival and circulating PSA. Cancer Epidemiology Biomarkers and Prevention (2006) 15:1142-1147.

Hayes VM, Severi G, Padilla EJD, Eggleton SA, Southey MC, Sutherland RL, Hopper JL, Giles GG. Genetic variants in the vitamin D receptor gene and prostate cancer risk. Cancer Epidemiology Biomarkers and Prevention (2005) 14:997-999.

Hayes VM, Severi G, Eggleton SA, Padilla EJD, Southey MC, Sutherland RL, Hopper JL, Giles GG. The E211G>A androgen receptor polymorphism is associated with a decreased risk of metastatic prostate cancer and androgenetic alopecia. Cancer Epidemiology Biomarkers and Prevention (2005) 14:993-996. 

More Garvan Publications