Immunology and Immunodeficiency Lab

Publications

Long-term outcome of LRBA deficiency in 76 patients after various treatment modalities as evaluated by the immune deficiency and dysregulation activity (IDDA) score
Tesch, V. K.; Abolhassani, H.; Shadur, B.; Zobel, J.; Mareika, Y.; Sharapova, S.; Karakoc-Aydiner, E.; Riviere, J. G.; Garcia-Prat, M.; Moes, N.; Haerynck, F.; Gonzales-Granado, L. I.; Santos Perez, J. L.; Mukhina, A.; Shcherbina, A.; Aghamohammadi, A.; Hammarstrom, L.; Dogu, F.; Haskologlu, S.; Ikinciogullari, A. I.; Kostel Bal, S.; Baris, S.; Kilic, S. S.; Karaca, N. E.; Kutukculer, N.; Girschick, H.; Kolios, A.; Keles, S.; Uygun, V.; Stepensky, P.; Worth, A.; van Montfrans, J. M.; Peters, A. M. J.; Meyts, I.; Adeli, M.; Marzollo, A.; Padem, N.; Khojah, A. M.; Chavoshzadeh, Z.; Avbelj Stefanija, M.; Bakhtiar, S.; Florkin, B.; Meeths, M.; Gamez, L.; Grimbacher, B.; Seppanen, M. R. J.; Lankester, A.; Gennery, A. R.; Seidel, M. G.; Inborn Errors, Clinical; Registry Working Parties of the European Society for, Blood; Marrow, Transplantation; the European Society for, Immunodeficiencies
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 145(5):1452-1463, 2020
Regulation of T follicular helper cell formation and function by antigen presenting cells
Deenick, E.K.; Ma, C.S.; Brink, R.; Tangye, S.G:
CURRENT OPINION IN IMMUNOLOGY (23):1, 2011
Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cells.
Suryani, S.; Fulcher, D. A.; Santner-Nanan, B.; Nanan, R.; Wong, M.; Shaw, P. J.; Gibson, J.; Williams, A.; Tangye, S. G.
Blood 115(3):519-29, 2010
Thucydides and longer-lived plasma cells
Tangye, S. G.
Blood 125(11):1684-5, 2015
Circulating TFH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity
Koutsakos, M., Wheatley, A. K., Loh, L., Clemens, E. B., Sant, S., Nüssing, S., Fox, A., Chung, A. W., Laurie, K. L., Hurt, A. C., Rockman, S., Lappas, M., Loudovaris, T., Mannering, S. I., Westall, G. P., Elliot, M., Tangye, S. G., Wakim, L. M., Kent, S. J., Nguyen, T. H. O., Kedzierska, K.
Science Translational Medicine 10(428):1-15, 2018
Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee
Tangye SG, Al-Herz W, Bousfiha A, Chatila T, Cunningham-Rundles C, Etzioni A, Franco JL, Holland SM, Klein C, Morio T, Ochs HD, Oksenhendler E, Picard C, Puck J, Torgerson TR, Casanova JL, Sullivan KE.
JOURNAL OF CLINICAL IMMUNOLOGY 2020
Memory B cells: total recall
Phan, TG.; Tangye, SG.
CURRENT OPINION IN IMMUNOLOGY 45:130-140, 2017
The role of BAFF and APRIL in regulating human B-cell behaviour: implications for disease pathogenesis
Tangye, S.G.; Fulcher, D.A.
Contemporary Immunology:BLys Ligands and Receptors :195-220, 2010
What can primary immunodeficiencies teach us about Th9 cell differentiation and function?
Worley, L; Ma, C; Tangye, SG
IMMUNOLOGY AND CELL BIOLOGY 97(4):380-388, 2019
Genetic susceptibility to EBV infection: insights from inborn errors of immunity
Tangye, S.G.
HUMAN GENETICS 139(6-7):885-901, 2020
Functional STAT3 deficiency compromises the generation of human T follicular helper cells
Ma, C. S.; Avery, D. T.; Chan, A.; Batten, M.; Bustamante, J.; Boisson-Dupuis, S.; Arkwright, P. D.; Kreins, A. Y.; Averbuch, D.; Engelhard, D.; Magdorf, K.; Kilic, S. S.; Minegishi, Y.; Nonoyama, S.; French, M. A.; Choo, S.; Smart, J. M.; Peake, J.; Wong, M.; Gray, P.; Cook, M. C.; Fulcher, D. A.; Casanova, J. L.; Deenick, E. K.; Tangye, S. G.
Blood 119(17):3997-4008, 2012
Characterization of the clinical and immunologic phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations
Lorenzini, T.; Fliegauf, M.; Klammer, N.; Frede, N.; Proietti, M.; Bulashevska, A.; Camacho-Ordonez, N.; Varjosalo, M.; Kinnunen, M.; de Vries, E.; van der Meer, J. W. M.; Ameratunga, R.; Roifman, C. M.; Schejter, Y. D.; Kobbe, R.; Hautala, T.; Atschekzei, F.; Schmidt, R. E.; Schroder, C.; Stepensky, P.; Shadur, B.; Pedroza, L. A.; van der Flier, M.; Martinez-Gallo, M.; Gonzalez-Granado, L. I.; Allende, L. M.; Shcherbina, A.; Kuzmenko, N.; Zakharova, V.; Neves, J. F.; Svec, P.; Fischer, U.; Ip, W.; Bartsch, O.; Baris, S.; Klein, C.; Geha, R.; Chou, J.; Alosaimi, M.; Weintraub, L.; Boztug, K.; Hirschmugl, T.; Dos Santos Vilela, M. M.; Holzinger, D.; Seidl, M.; Lougaris, V.; Plebani, A.; Alsina, L.; Piquer-Gibert, M.; Deya-Martinez, A.; Slade, C. A.; Aghamohammadi, A.; Abolhassani, H.; Hammarstrom, L.; Kuismin, O.; Helminen, M.; Allen, H. L.; Thaventhiran, J. E.; Freeman, A. F.; Cook, M.; Bakhtiar, S.; Christiansen, M.; Cunningham-Rundles, C.; Patel, N. C.; Rae, W.; Niehues, T.; Brauer, N.; Syrjanen, J.; Seppanen, M. R. J.; Burns, S. O.; Tuijnenburg, P.; Kuijpers, T. W.; BioResource, Nihr; Warnatz, K.; Grimbacher, B.; BioResource, Nihr
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 146(4):901-911, 2020
Refractory very early-onset inflammatory bowel disease associated with cytosolic isoleucyl-tRNA synthetase deficiency: A case report
Fagbemi, A.; Newman, W. G.; Tangye, S. G.; Hughes, S. M.; Cheesman, E.; Arkwright, P. D.
WORLD JOURNAL OF GASTROENTEROLOGY 26(15):1841-1846, 2020
The Clinical Immunogenomics Research Consortium Australasia (CIRCA): a Distributed Network Model for Genomic Healthcare Delivery
Phan, Tri Giang; Gray, Paul E.; Wong, Melanie; Macintosh, Rebecca; Burnett, Leslie; Tangye, Stuart G.; on behalf of, Circa
JOURNAL OF CLINICAL IMMUNOLOGY 40(5):763-766, 2020
Coronavirus disease 2019 in patients with inborn errors of immunity: lessons learned
Bucciol, G.; Tangye, S. G.; Meyts, I.
CURRENT OPINION IN PEDIATRICS 33(6):648-656, 2021
Human CD8(+) T cell cross-reactivity across influenza A, B and C viruses
Koutsakos, M.; Illing, P. T.; Nguyen, T. H. O.; Mifsud, N. A.; Crawford, J. C.; Rizzetto, S.; Eltahla, A. A.; Clemens, E. B.; Sant, S.; Chua, B. Y.; Wong, C. Y.; Allen, E. K.; Teng, D.; Dash, P.; Boyd, D. F.; Grzelak, L.; Zeng, W.; Hurt, A. C.; Barr, I.; Rockman, S.; Jackson, D. C.; Kotsimbos, T. C.; Cheng, A. C.; Richards, M.; Westall, G. P.; Loudovaris, T.; Mannering, S. I.; Elliott, M.; Tangye, S. G.; Wakim, L. M.; Rossjohn, J.; Vijaykrishna, D.; Luciani, F.; Thomas, P. G.; Gras, S.; Purcell, A. W.; Kedzierska, K.
NATURE IMMUNOLOGY 20(5):613-625, 2019
It's that time of year-APRIL promotes humoral immunity in humans
Tangye, S. G.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 146(5):1013-1015, 2020
Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification
Bousfiha A, Jeddane L, Picard C, Al-Herz W, Ailal F, Chatila T, Cunningham-Rundles C, Etzioni A, Franco JL, Holland SM, Klein C, Morio T, Ochs HD, Oksenhendler E, Puck J, Torgerson TR, Casanova JL, Sullivan KE, Tangye SG.
JOURNAL OF CLINICAL IMMUNOLOGY 40(1):66-81, 2020
Mechanisms underlying host defense and disease pathology in response to severe acute respiratory syndrome (SARS)-CoV2 infection: insights from inborn errors of immunity
Tangye, S.; Bucciol, G.; Meyts, I.
Current Opinion in Allergy and Clinical Immunology 21(6):515-524, 2021
Autoimmunity: IL-21: a new player in Th17-cell differentiation
Deenick, E. K.;Tangye, S. G. :
IMMUNOLOGY AND CELL BIOLOGY 85(7):503-5, 2007
An essential role for the Zn(2+) transporter ZIP7 in B cell development
Anzilotti, C.; Swan, D. J.; Boisson, B.; Deobagkar-Lele, M.; Oliveira, C.; Chabosseau, P.; Engelhardt, K. R.; Xu, X.; Chen, R.; Alvarez, L.; Berlinguer-Palmini, R.; Bull, K. R.; Cawthorne, E.; Cribbs, A. P.; Crockford, T. L.; Dang, T. S.; Fearn, A.; Fenech, E. J.; de Jong, S. J.; Lagerholm, B. C.; Ma, C. S.; Sims, D.; van den Berg, B.; Xu, Y.; Cant, A. J.; Kleiner, G.; Leahy, T. R.; de la Morena, M. T.; Puck, J. M.; Shapiro, R. S.; van der Burg, M.; Chapman, J. R.; Christianson, J. C.; Davies, B.; McGrath, J. A.; Przyborski, S.; Santibanez Koref, M.; Tangye, S. G.; Werner, A.; Rutter, G. A.; Padilla-Parra, S.; Casanova, J. L.; Cornall, R. J.; Conley, M. E.; Hambleton, S.
NATURE IMMUNOLOGY 20(3):350-361, 2019
Tuberculosis and impaired IL-23–dependent IFN- immunity in humans homozygous for a common TYK2 missense variant
Stéphanie Boisson-Dupuis1,2,3*†, Noe Ramirez-Alejo1†, Zhi Li4,5‡, Etienne Patin6,7,8‡, Geetha Rao9‡, Gaspard Kerner2,3‡, Che Kang Lim10,11‡, Dimitry N. Krementsov12‡, Nicholas Hernandez1, Cindy S. Ma9,13, Qian Zhang14, Janet Markle1, Ruben Martinez-Barricarte1, Kathryn Payne9, Robert Fisch1, Caroline Deswarte2,3, Joshua Halpern1, Matthieu Bouaziz2,3, Jeanette Mulwa1, Durga Sivanesan15,16, Tomi Lazarov17, Rodrigo Naves18, Patricia Garcia19, Yuval Itan1,20,21, Bertrand Boisson1,2,3, Alix Checchi2,3, Fabienne Jabot-Hanin2,3, Aurélie Cobat2,3, Andrea Guennoun14, Carolyn C. Jackson1,22, Sevgi Pekcan23, Zafer Caliskaner24, Jaime Inostroza25, Beatriz Tavares Costa-Carvalho26, Jose Antonio Tavares Albuquerque27, Humberto Garcia-Ortiz28, Lorena Orozco28, Tayfun Ozcelik29, Ahmed Abid30, Ismail Abderahmani Rhorfi31, Hicham Souhi30, Hicham Naji Amrani30, Adil Zegmout30, Frédéric Geissmann17, Stephen W. Michnick15, Ingrid Muller-Fleckenstein31, Bernhard Fleckenstein31, Anne Puel1,2,3, Michael J. Ciancanelli1, Nico Marr32, Hassan Abolhassani10,33, Maria Elvira Balcells34, Antonio Condino-Neto27, Alexis Strickler35, Katia Abarca36, Cory Teuscher37, Hans D. Ochs38, Ismail Reisli39, Esra H. Sayar39, Jamila El-Baghdadi40, Jacinta Bustamante1,2,3,41§, Lennart Hammarström10,11,42§, Stuart G. Tangye9,13§, Sandra Pellegrini4,5§, Lluis Quintana-Murci6,7,8§, Laurent Abel1,2,3||, Jean-Laurent Casanova
Science Immunology 3(30):pii: eaau8714, 2018
Coronavirus disease 2019 in patients with inborn errors of immunity: An international study
Meyts, I.; Bucciol, G.; Quinti, I.; Neven, B.; Fischer, A.; Seoane, E.; Lopez-Granados, E.; Gianelli, C.; Robles-Marhuenda, A.; Jeandel, P. Y.; Paillard, C.; Sankaran, V. G.; Demirdag, Y. Y.; Lougaris, V.; Aiuti, A.; Plebani, A.; Milito, C.; Dalm, V. A.; Guevara-Hoyer, K.; Sanchez-Ramon, S.; Bezrodnik, L.; Barzaghi, F.; Gonzalez-Granado, L. I.; Hayman, G. R.; Uzel, G.; Mendonca, L. O.; Agostini, C.; Spadaro, G.; Badolato, R.; Soresina, A.; Vermeulen, F.; Bosteels, C.; Lambrecht, B. N.; Keller, M.; Mustillo, P. J.; Abraham, R. S.; Gupta, S.; Ozen, A.; Karakoc-Aydiner, E.; Baris, S.; Freeman, A. F.; Yamazaki-Nakashimada, M.; Scheffler-Mendoza, S.; Espinosa-Padilla, S.; Gennery, A. R.; Jolles, S.; Espinosa, Y.; Poli, M. C.; Fieschi, C.; Hauck, F.; Cunningham-Rundles, C.; Mahlaoui, N.; Immunity, Iuis Committee of Inborn Errors of; Warnatz, K.; Sullivan, K. E.; Tangye, S. G.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 147(2):520-531, 2021
How we approach: Severe congenital neutropenia and myelofibrosis due to mutations in VPS45
Shadur, B.; Asherie, N.; Newburger, P. E.; Stepensky, P.
PEDIATRIC BLOOD & CANCER 66(1):e27473, 2019
Cytokine-Mediated Regulation of Human Lymphocyte Development and Function: Insights from Primary Immunodeficiencies
Tangye, S. G.; Pelham, S. J.; Deenick, E. K.; Ma, C. S.
JOURNAL OF IMMUNOLOGY 199(6):1949-1958, 2017
Genetic cause of immune dysregulation - one gene or two?
Tangye, S. G.
JOURNAL OF CLINICAL INVESTIGATION 126(11):4065-4067, 2016
Low IgE Is Insufficiently Sensitive to Guide Genetic Testing of STAT3 Gain-of-Function Mutations
Tangye, S. G.; Forbes, L. R.; Leiding, J.; Preece, K.; Kumar, A. R.; Gambineri, E.; Milner, J. D.; Cooper, M. A.; Seppanen, M.
CLINICAL CHEMISTRY 63(9):1539-1540, 2017
Respiratory manifestations in LPS-responsive beige-like anchor (LRBA) protein-deficient patients
Shamriz, O.; Shadur, B.; NaserEddin, A.; Zaidman, I.; Simanovsky, N.; Elpeleg, O.; Kerem, E.; Reiter, J.; Stepensky, P.
EUROPEAN JOURNAL OF PEDIATRICS 177(8):1163-1172, 2018
SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease?
Sancho-Shimizu, V.; Brodin, P.; Cobat, A.; Biggs, C.M.; Toubiana, J.; Lucas, C.L.; Henrickson, S.E.; Belot, A.; Tangye, S.G.; Milner, J.D.; Levin, M.; Abel, L.; Bogunovic, D.; Casanova, J.L.; Zhang, S.Y.
JOURNAL OF EXPERIMENTAL MEDICINE 218(6) 2021
Successful hematopoietic stem cell transplantation for osteopetrosis using reduced intensity conditioning
Shadur, B.; Zaidman, I.; NaserEddin, A.; Lokshin, E.; Hussein, F.; Oron, H. C.; Avni, B.; Grisariu, S.; Stepensky, P.
PEDIATRIC BLOOD & CANCER 65(6):e27010, 2018
Refractory very early-onset inflammatory bowel disease associated with cytosolic isoleucyl-tRNA synthetase deficiency: A case report.
Fagbemi, A., Newman, WG., Tangye, SG., Hughes, SM., Cheesman. E., Arkwright,PD.
WORLD JOURNAL OF GASTROENTEROLOGY 26(15):1841-1846, 2020
Human IgM+CD27+ B cells: memory B cells or ""memory"" B cells?
Tangye, S. G.;Good, K. L. :
JOURNAL OF IMMUNOLOGY 179(1):13-9, 2007
The Next Generation of Diagnostic Tests for Primary Immunodeficiency Disorders
French, M. A.; Tangye, S. G.
JOURNAL OF INFECTIOUS DISEASES 221(8):1232-1234, 2020
Haematopoietic stem cell induction by somite-derived endothelial cells controlled by meox1
Nguyen, P. D.
; Hollway, G. E.
; Sonntag, C.
; Miles, L. B.
; Hall, T. E.
; Berger, S.
; Fernandez, K. J.
; Gurevich, D. B.
; Cole, N. J.
; Alaei, S.
; Ramialison, M.
; Sutherland, R. L.
; Polo, J. M.
; Lieschke, G. J.
; Currie, P. D.;
NATURE 512(7514):314-8, 2014
To B1 or not to B1 ? that really is the question!
Tangye, S. G.
Blood 121(26):5109-10, 2013
Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation
Infantino, S.; Light, A.; O'Donnell, K.; Bryant, V.; Avery, D. T.; Elliott, M.; Tangye, S. G.; Belz, G.; Mackay, F.; Richard, S.; Tarlinton, D.
Nature Communications 8(1):891, 2017
Memory B cells: effectors of long-lived immune responses
Tangye, S. G.; Tarlinton, D. M.;
EUROPEAN JOURNAL OF IMMUNOLOGY 39(8):2065-75, 2009
Human inborn errors of the actin cytoskeleton affecting immunity: way beyond WAS and WIP
Tangye, S. G.; Bucciol, G.; de Las Casas, J. M.; Pillay, B.; Ma, C. S.; Moens, L.; Meyts, I.
IMMUNOLOGY AND CELL BIOLOGY 97(4):389-402, 2019
The origins, function, and regulation of T follicular helper cells
Ma, C. S.; Deenick, E. K.; Batten, M.; Tangye, S. G.
JOURNAL OF EXPERIMENTAL MEDICINE 209(7):1241-53, 2012
Human immunity against EBV—lessons from the clinic
Tangye,SG.; Palendira, U.; Edwards, ES.
JOURNAL OF EXPERIMENTAL MEDICINE 214(1):269-283, 2017
CD4(+) T cells that help B cells - a proposal for uniform nomenclature
Eisenbarth, S. C.; Baumjohann, D.; Craft, J.; Fazilleau, N.; Ma, C. S.; Tangye, S. G.; Vinuesa, C. G.; Linterman, M. A.
TRENDS IN IMMUNOLOGY 42(8):658-669, 2021
The good, the bad and the ugly - TFH cells in human health and disease
Tangye, S. G.; Ma, C. S.; Brink, R.; Deenick, E. K.
NATURE REVIEWS IMMUNOLOGY 13(6):412-26, 2013
Scube activity is necessary for Hedgehog signal transduction in vivo.
Johnson, J-L.F.A.; Hall, T.E.; Dyson, J.M.; Sonntag, C.; Ayers, K.; Berger, S.; Gautier, P.; Mitchell, C.; Hollway, G.E.; Currie, P.D.;
DEVELOPMENTAL BIOLOGY 368(2):193-202, 2012
Three copies of four interferon receptor genes underlie mucocutaneous candidiasis and auto-immune thyroiditis in patients with Down Syndrome
XF Kong, L Worley, D Rinchai, V Bondet, D Duffy, P Veettil Jithesh, M Goulet, E Nonnotte, N Gürtler, L Liu, M Migaud, CS Ma, J Bustamante, L Abel, S Boisson-Dupuis, A Ravel, S Lyonnet, D Chaussabel, SG Tangye, JL Casanova, A Puel.
JOURNAL OF CLINICAL IMMUNOLOGY 40:807-819, 2020
Elucidating the effects of disease-causing mutations on STAT3 function in autosomal-dominant hyper-IgE syndrome
Pelham, S. J.
; Lenthall, H. C.
; Deenick, E. K.
; Tangye, S. G.;
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 138(4):1210-1213 e5, 2016
Germline-activating mutations in PIK3CD compromise B cell development and function
Avery, D. T.; Kane, A.; Nguyen, T.; Lau, A.; Nguyen, A.; Lenthall, H.; Payne, K.; Shi, W.; Brigden, H.; French, E.; Bier, J.; Hermes, J. R.; Zahra, D.; Sewell, W. A.; Butt, D.; Elliott, M.; Boztug, K.; Meyts, I.; Choo, S.; Hsu, P.; Wong, M.; Berglund, L. J.; Gray, P.; O'Sullivan, M.; Cole, T.; Holland, S. M.; Ma, C. S.; Burkhart, C.; Corcoran, L. M.; Phan, T. G.; Brink, R.; Uzel, G.; Deenick, E. K.; Tangye, S. G.
JOURNAL OF EXPERIMENTAL MEDICINE 215(8):2073-2095, 2018
Dedicator of cytokinesis 8-deficient CD4+ T cells are biased to a TH2 effector fate at the expense of TH1 and TH17 cells.
Tangye, SG.; Pillay, B.; Randall, L.; Avery, DT.; Phan, TG.; Gray, P.; Ziegler, JB.; Smart,JM.; Choo, S.; Peake, J.; Arkwright,PD.; Hambleton, S.; Oswaldo Lugo Reyes, S.; Orange, J.; Freeman, AF.; Uzel, G.; Su, HC.; Goodnow, CG.; Casanova, JL.; Ma, CS.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 139:933-949, 2017
The right ""Job"" for STAT3 mutant mice!
Tangye, S. G.
Blood 123(19):2907-9, 2014
B cells race the clock to get a second wind
Phan, T. G.; Tangye, S. G.
NATURE IMMUNOLOGY 19:791-793, 2018
Plasmacytoid DCs induce gutsy plasma cells.
Tangye, S.
IMMUNITY 34(2):144-6, 2011
Decreased expression of Kruppel-like factors in memory B cells induces the rapid response typical of secondary antibody responses
Good, K. L.;Tangye, S. G. :
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104(33):13420-5, 2007
T(+) NK(+) IL-2 Receptor gamma Chain Mutation: a Challenging Diagnosis of Atypical Severe Combined Immunodeficiency
Stepensky, P.; Keller, B.; Shamriz, O.; von Spee-Mayer, C.; Friedmann, D.; Shadur, B.; Unger, S.; Fuchs, S.; NaserEddin, A.; Rumman, N.; Amro, S.; Molho Pessach, V.; Abuzaitoun, O.; Somech, R.; Elpeleg, O.; Ehl, S.; Warnatz, K.
JOURNAL OF CLINICAL IMMUNOLOGY 38(4):527-536, 2018
Everolimus-Induced Remission of Classic Kaposi's Sarcoma Secondary to Cryptic Splicing Mediated CTLA4 Haploinsufficiency
Yap JY, Gloss B, Batten M, Hsu P, Berglund L, Cai F, Dai P, Parker A, Qiu M, Miley W, Roshan R, Marshall V, Whitby D, Wegman E, Garsia R, Wu KHC, Kirk E, Polizzotto M, Deenick EK, SG Tangye, Ma CS, CIRCA, Phan TG
JOURNAL OF CLINICAL IMMUNOLOGY 40(5) 2020
T cells require DOCK8 for flexibility and function
Tangye, S. G.;
JOURNAL OF EXPERIMENTAL MEDICINE 211(13):2482-3, 2014
Coronavirus disease 2019 in patients with inborn errors of immunity: An international study
Meyts, I. Bucciol, G. Quinti, I. Neven, B. Fischer, A. Seoane, E. Lopez-Granados, E. Gianelli, C. Robles-Marhuenda, A. Jeandel, P. Y. Paillard, C. Sankaran, V. G. Demirdag, Y. Y. Lougaris, V. Aiuti, A. Plebani, A. Milito, C. Dalm, V. A. Guevara-Hoyer, K. Sanchez-Ramon, S. Bezrodnik, L. Barzaghi, F. Gonzalez-Granado, L. I. Hayman, G. R. Uzel, G. Mendonca, L. O. Agostini, C. Spadaro, G. Badolato, R. Soresina, A. Vermeulen, F. Bosteels, C. Lambrecht, B. N. Keller, M. Mustillo, P. J. Abraham, R. S. Gupta, S. Ozen, A. Karakoc-Aydiner, E. Baris, S. Freeman, A. F. Yamazaki-Nakashimada, M. Scheffler-Mendoza, S. Espinosa-Padilla, S. Gennery, A. R. Jolles, S. Espinosa, Y. Poli, M. C. Fieschi, C. Hauck, F. Cunningham-Rundles, C. Mahlaoui, N. Iuis Committee of Inborn Errors of Immunity Warnatz, K. Sullivan, K. E. Tangye, S. G.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 147(2):520.531, 2021
XLP: clinical features and molecular etiology due to mutations in SH2D1A encoding SAP
Tangye, S. G.
JOURNAL OF CLINICAL IMMUNOLOGY 34:772-779, 2014
The Evidence for Allogeneic Hematopoietic Stem Cell Transplantation for Congenital Neutrophil Disorders: A Comprehensive Review by the Inborn Errors Working Party Group of the EBMT
Bakhtiar, S.; Shadur, B.; Stepensky, P.
Frontiers in Pediatrics 7:436, 2019
Regulation of the germinal center and humoral immunity by interleukin-21
Tangye, S. G.; Ma, C. S.
JOURNAL OF EXPERIMENTAL MEDICINE 217(1):e20191638, 2020
Unresponsiveness to inhaled antigen is governed by conventional dendritic cells and overridden during infection by monocytes
Bedford, J. G.; Heinlein, M.; Garnham, A. L.; Nguyen, T. H. O.; Loudovaris, T.; Ge, C.; Mannering, S. I.; Elliott, M.; Tangye, S. G.; Kedzierska, K.; Gray, D. H. D.; Heath, W. R.; Wakim, L. M.
Science Immunology 5(52):eabb5439, 2020
Combined immunodeficiency and Epstein-Barr virus-induced B cell malignancy in humans with inherited CD70 deficiency.
Abolhassani, H.; Edwards E.; Ikinciogullari, A.; Jing, H.; Borte, S.; Buggert, M.; Du, L.; Matsuda-Lennikov,M.; Romano, R.; Caridha, R.; Bade, S.; Zhang, Y.; Frederiksen, J.; Fang, M.; Kostel Bal, S.; Haskologlu, S.; Dogu, F.; Tacyildiz, N.; Matthews, HF.; McElwee, JJ.; Gostick, E.; Price, DA.; Palendira, U.; Aghamohammadi, A.; Boisson, B.; Rezaei, N.; Karlsson, AC.; Lenardo, MJ.; Casanova, JL.; Hammarström, L.; Tangye, SG.; Su, HC.; Pan-Hammarström, P.
J EXP MED 214(1):91-106, 2017
CD8(+) T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph
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Nature Communications 12(1):2931, 2021
Molecular pathogenesis of EBV susceptibility in XLP as revealed by analysis of female carriers with heterozygous expression of SAP
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PLOS BIOL 9(11):e1001187, 2011
Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency
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JOURNAL OF CLINICAL INVESTIGATION 127(5):1991-2006, 2017
The Broad Clinical Spectrum and Transplant Results of PNP Deficiency
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JOURNAL OF CLINICAL IMMUNOLOGY 2020
International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee Report on Inborn Errors of Immunity
Picard, C.; Bobby Gaspar, H.; Al-Herz, W.; Bousfiha, A.; Casanova, J. L.; Chatila, T.; Crow, Y. J.; Cunningham-Rundles, C.; Etzioni, A.; Franco, J. L.; Holland, S. M.; Klein, C.; Morio, T.; Ochs, H. D.; Oksenhendler, E.; Puck, J.; Tang, M. L. K.; Tangye, S. G.; Torgerson, T. R.; Sullivan, K. E.
JOURNAL OF CLINICAL IMMUNOLOGY 38(1):96-128, 2018
STAT3 is required for IL-21-induced secretion of IgE from human naive B cells
Avery, D. T.;Ma, C. S.;Bryant, V. L.;Santner-Nanan, B.;Nanan, R.;Wong, M.;Fulcher, D. A.;Cook, M. C.;Tangye, S. G. :
Blood 112(5):1784-93, 2008
Human IFN-y immunity to mycobacteria is governed by both IL-12 and IL-23
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Science Immunology 3(30):eaau6759, 2018
AD Hyper-IgE Syndrome Due to a Novel Loss-of-Function Mutation in STAT3: a Diagnostic Pursuit Won by Clinical Acuity.
Moens, L.; Schaballie, H.; Bosch, B.; Voet, A.; Bossuyt, X.; Casanova, JL.; Boisson-Dupuis, S.; Tangye, SG.; Meyts, I.
JOURNAL OF CLINICAL IMMUNOLOGY 37(1):12-17, 2017
Primary immune deficiencies affecting lymphocyte differentiation: lessons from the spectrum of resulting infections
Cook, M. C.; Tangye, S. G.;
INTERNATIONAL IMMUNOLOGY 21(9):1003-11, 2009
Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to multiple infectious agents
Levy, R.; Langlais, D.; Beziat, V.; Rapaport, F.; Rao, G.; Lazarov, T.; Bourgey, M.; Zhou, Y. J.; Briand, C.; Moriya, K.; Ailal, F.; Avery, D. T.; Markle, J.; Lim, A. I.; Ogishi, M.; Yang, R.; Pelham, S.; Emam, M.; Migaud, M.; Deswarte, C.; Habib, T.; Saraiva, L. R.; Moussa, E. A.; Guennoun, A.; Boisson, B.; Belkaya, S.; Martinez-Barricarte, R.; Rosain, J.; Belkadi, A.; Breton, S.; Payne, K.; Benhsaien, I.; Plebani, A.; Lougaris, V.; Di Santo, J. P.; Neven, B.; Abel, L.; Ma, C. S.; Bousfiha, A. A.; Marr, N.; Bustamante, J.; Liu, K.; Gros, P.; Geissmann, F.; Tangye, S. G.; Casanova, J. L.; Puel, A.
JOURNAL OF CLINICAL INVESTIGATION 131(17):e150143, 2021
The Expanding Spectrum of NFkB1 Deficiency
Bryant, V.; Tangye, SG.;
JOURNAL OF CLINICAL IMMUNOLOGY (36):531-532, 2016
Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules
Ma, C. S.;Nichols, K. E.;Tangye, S. G. :
Annual Review of Immunology 25:337-79, 2007
IRF4 haploinsufficiency in a family with Whipple's disease
Guerin, A.; Kerner, G.; Marr, N.; Markle, J. G.; Fenollar, F.; Wong, N.; Boughorbel, S.; Avery, D. T.; Ma, C. S.; Bougarn, S.; Bouaziz, M.; Beziat, V.; Della Mina, E.; Oleaga-Quintas, C.; Lazarovt, T.; Worley, L.; Nguyen, T.; Patin, E.; Deswarte, C.; Martinez-Barricarte, R.; Boucherit, S.; Ayral, X.; Edouard, S.; Boisson-Dupuis, S.; Rattina, V.; Bigio, B.; Vogt, G.; Geissmann, F.; Quintana-Murci, L.; Chaussabel, D.; Tangye, S. G.; Raoult, D.; Abel, L.; Bustamante, J.; Casanova, J. L.
eLife 7(7):e32340, 2018
Successful treatment with daratumumab for post-HSCT refractory hemolytic anemia
Even-Or, E.; Naser Eddin, A.; Shadur, B.; Dinur Schejter, Y.; Najajreh, M.; Zelig, O.; Zaidman, I.; Stepensky, P.
PEDIATRIC BLOOD & CANCER 67(1):e28010, 2020
The 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies
Bousfiha, A.; Jeddane, L.; Picard, C.; Ailal, F.; Bobby Gaspar, H.; Al-Herz, W.; Chatila, T.; Crow, Y. J.; Cunningham-Rundles, C.; Etzioni, A.; Franco, J. L.; Holland, S. M.; Klein, C.; Morio, T.; Ochs, H. D.; Oksenhendler, E.; Puck, J.; Tang, M. L. K.; Tangye, S. G.; Torgerson, T. R.; Casanova, J. L.; Sullivan, K. E.
JOURNAL OF CLINICAL IMMUNOLOGY 38(1):129-143, 2018
Human inborn errors of immunity to herpes viruses
Jouanguy, E.; Beziat, V.; Mogensen, T. H.; Casanova, J. L.; Tangye, S. G.; Zhang, S. Y.
CURRENT OPINION IN IMMUNOLOGY 62:106-122, 2020
T cell/B cell interactions in primary immunodeficiencies
Tangye, S.G; Deenick, E.K; Palendira, U.; Ma, C.S:
Annals of the New York Academy of Sciences 1250:1-13, 2012
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths
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Science Immunology 6(62):eabl4340, 2021
BAFF, APRIL and human B cell disorders
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SEMINARS IN IMMUNOLOGY 18(5):305-17, 2006
Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function, and EBV immunity
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 143(1):276-291, 2019
Mutations affecting the actin regulator WDR1 lead to aberrant lymphoid immunity
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 142(5):1589-1604, 2018
Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 143(1):276-291 e6, 2019
Human STAT3 variants underlie autosomal dominant hyper-IgE syndrome by negative dominance
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JOURNAL OF EXPERIMENTAL MEDICINE 218(8):e20202592, 2021
Tissue-resident regulatory T cells accumulate at human barrier lymphoid organs
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IMMUNOLOGY AND CELL BIOLOGY 2021
IL-21 is the primary common gamma chain-binding cytokine required for human B-cell differentiation in vivo
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Blood 118(26):6824-35, 2011
Hematopoietic Stem Cell Transplantation Cures Chronic Aichi Virus Infection in a Patient with X-linked Agammaglobulinemia
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JOURNAL OF CLINICAL IMMUNOLOGY 41(6):1403-1405, 2021
Systemic Inflammation and Myelofibrosis in a Patient with Takenouchi-Kosaki Syndrome due to CDC42 Tyr64Cys Mutation
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JOURNAL OF CLINICAL IMMUNOLOGY 40(4):567-570, 2020
Phosphatidylinositol 3-kinase signaling and immune regulation: insights into disease pathogenesis and clinical implications
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Expert Review of Clinical Immunology 17(8):905-914, 2021
Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome
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JOURNAL OF EXPERIMENTAL MEDICINE 217(6):e20191804, 2020
The TORC that Gets the GC Cycling
Deenick, EK.; Tangye, SG.
IMMUNITY 46:974-976, 2017
IL-21-induced isotype switching to IgG and IgA by human naive B cells is differentially regulated by IL-4
Avery, D. T.; Bryant, V. L.; Ma, C. S.; de Waal Malefyt, R.; Tangye, S. G.
JOURNAL OF IMMUNOLOGY 181(3):1767-79, 2008
Advances in IL-21 biology - enhancing our understanding of human disease
Tangye, S. G.
CURRENT OPINION IN IMMUNOLOGY 34:107-115, 2015
Editorial overview: Lymphocyte activation and effector functions
Reynaud, C. A.; Tangye, S.
CURRENT OPINION IN IMMUNOLOGY 28:v-vii, 2014
Intrinsic Defects in B Cell Development and Differentiation, T Cell Exhaustion and Altered Unconventional T Cell Generation Characterize Human Adenosine Deaminase Type 2 Deficiency
Yap, J. Y.; Moens, L.; Lin, M. W.; Kane, A.; Kelleher, A.; Toong, C.; Wu, K. H. C.; Sewell, W. A.; Phan, T. G.; Hollway, G. E.; Enthoven, K.; Gray, P. E.; Casas-Martin, J.; Wouters, C.; De Somer, L.; Hershfield, M.; Bucciol, G.; Delafontaine, S.; Ma, C. S.; Tangye, S. G.; Meyts, I.
JOURNAL OF CLINICAL IMMUNOLOGY 41(8):1915-1935, 2021
Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency
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BLOOD 136(23):2638-2655, 2020
Circulating TFH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity
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Science Translational Medicine 10(428) 2018
Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria
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CELL 183(7):1826-1847 e31, 2020
Staying alive: regulation of plasma cell survival
Tangye, S. G.
TRENDS IN IMMUNOLOGY 32(12):595-602, 2011
Human DOCK2 Deficiency: Report of a Novel Mutation and Evidence for Neutrophil Dysfunction
Moens, L.; Gouwy, M.; Bosch, B.; Pastukhov, O.; Nieto-Patlan, A.; Siler, U.; Bucciol, G.; Mekahli, D.; Vermeulen, F.; Desmet, L.; Maebe, S.; Flipts, H.; Corveleyn, A.; Moshous, D.; Philippet, P.; Tangye, S. G.; Boisson, B.; Casanova, J. L.; Florkin, B.; Struyf, S.; Reichenbach, J.; Bustamante, J.; Notarangelo, L. D.; Meyts, I.
JOURNAL OF CLINICAL IMMUNOLOGY 39(3):298-308, 2019
Flow Cytometric-Based Analysis of Defects in Lymphocyte Differentiation and Function Due to Inborn Errors of Immunity
Ma, C. S.; Tangye, S. G.
Frontiers in Immunology 10:2108, 2019
A deep intronic splice mutation of STAT3 underlies hyper IgE syndrome by negative dominance
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116(33):16463-16472, 2019
STAT3 regulates cytotoxicity of human CD57+ CD4+ T cells in blood and lymphoid follicles
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Scientific Reports 8(1):3529, 2018
Combined Immunodeficiency with Ring Chromosome 21
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JOURNAL OF CLINICAL IMMUNOLOGY 38(3):251-256, 2018
Molecular requirements for human lymphopoiesis as defined by inborn errors of immunity
Della Mina, E., Guerin, A., Tangye, S. G.
STEM CELLS 39(4):389-402, 2021
Naïve and memory B cells exhibit distinct biochemical responses following BCR engagement
Moens, L.; Kane, A.; Tangye, SG.
IMMUNOLOGY AND CELL BIOLOGY 94(8):774-786, 2016
Chronic mucocutaneous candidiasis and connective tissue disorder in humans with impaired JNK1-dependent responses to IL-17A/F and TGF-beta
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Science Immunology 4(41):eaax7965, 2019
Pathogenic CD4+ T cells regulating B-cell differentiation in autoimmunity: not exactly Tfh cells.
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IMMUNOLOGY AND CELL BIOLOGY 95:419-421, 2017
Genomic Spectrum and Phenotypic Heterogeneity of Human IL-21 Receptor Deficiency
Cagdas, D. Mayr, D. Baris, S. Worley, L. Langley, D. B. Metin, A. Aytekin, E. S. Atan, R. Kasap, N. Bal, S. K. Dmytrus, J. Heredia, R. J. Karasu, G. Torun, S. H. Toyran, M. Karakoc-Aydiner, E. Christ, D. Kuskonmaz, B. Uckan-Cetinkaya, D. Uner, A. Oberndorfer, F. Schiefer, A. I. Uzel, G. Deenick, E. K. Keller, B. Warnatz, K. Neven, B. Durandy, A. Sanal, O. Ma, C. S. Ozen, A. Stepensky, P. Tezcan, I. Boztug, K. Tangye, S. G.
JOURNAL OF CLINICAL IMMUNOLOGY 2021
Management of XLP-1 and ITK deficiency: The challenges posed by PID with an unpredictable spectrum of disease manifestations
Shadur, B.; Abuzaitoun, O.; NaserEddin, A.; Even-Or, E.; Zaidman, I.; Stepensky, P.
CLINICAL IMMUNOLOGY 198:39-45, 2019
High Th2 cytokine levels and upper airway inflammation in human inherited T-bet deficiency
Yang, R.; Weisshaar, M.; Mele, F.; Benhsaien, I.; Dorgham, K.; Han, J.; Croft, C. A.; Notarbartolo, S.; Rosain, J.; Bastard, P.; Puel, A.; Fleckenstein, B.; Glimcher, L. H.; Di Santo, J. P.; Ma, C. S.; Gorochov, G.; Bousfiha, A.; Abel, L.; Tangye, S. G.; Casanova, J. L.; Bustamante, J.; Sallusto, F.
JOURNAL OF EXPERIMENTAL MEDICINE 218(8):e20202726, 2021
Human plasma C3 is essential for the development of memory B, but not T, lymphocytes
Jimenez-Reinoso, A.; Marin, A. V.; Subias, M.; Lopez-Lera, A.; Roman-Ortiz, E.; Payne, K.; Ma, C. S.; Arbore, G.; Kolev, M.; Freeley, S. J.; Kemper, C.; Tangye, S. G.; Fernandez-Malave, E.; Rodriguez de Cordoba, S.; Lopez-Trascasa, M.; Regueiro, J. R.
JOURNAL OF CLINICAL IMMUNOLOGY 141(3):1153-1154, 2018
A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity
Beziat, V.; Li, J.; Lin, J. X.; Ma, C. S.; Li, P.; Bousfiha, A.; Pellier, I.; Zoghi, S.; Baris, S.; Keles, S.; Gray, P.; Du, N.; Wang, Y.; Zerbib, Y.; Levy, R.; Leclercq, T.; About, F.; Lim, A. I.; Rao, G.; Payne, K.; Pelham, S. J.; Avery, D. T.; Deenick, E. K.; Pillay, B.; Chou, J.; Guery, R.; Belkadi, A.; Guerin, A.; Migaud, M.; Rattina, V.; Ailal, F.; Benhsaien, I.; Bouaziz, M.; Habib, T.; Chaussabel, D.; Marr, N.; El-Benna, J.; Grimbacher, B.; Wargon, O.; Bustamante, J.; Boisson, B.; Muller-Fleckenstein, I.; Fleckenstein, B.; Chandesris, M. O.; Titeux, M.; Fraitag, S.; Alyanakian, M. A.; Leruez-Ville, M.; Picard, C.; Meyts, I.; Di Santo, J. P.; Hovnanian, A.; Somer, A.; Ozen, A.; Rezaei, N.; Chatila, T. A.; Abel, L.; Leonard, W. J.; Tangye, S. G.; Puel, A.; Casanova, J. L.
Science Immunology 3(24) 2018
Diversity of XMEN Disease: Description of 2 Novel Variants and Analysis of the Lymphocyte Phenotype
Klinken, E. M.; Gray, P. E.; Pillay, B.; Worley, L.; Edwards, E. S. J.; Payne, K.; Bennetts, B.; Hung, D.; Wood, B. A.; Chan, J. J.; Marshall, G. M.; Mitchell, R.; Uzel, G.; Ma, C. S.; Tangye, S. G.; McLean-Tooke, A.
JOURNAL OF CLINICAL IMMUNOLOGY 40(2):299-309, 2020
Stem cell transplantation for osteopetrosis in patients beyond the age of 5 years
Stepensky, P.; Grisariu, S.; Avni, B.; Zaidman, I.; Shadur, B.; Elpeleg, O.; Sirin, M.; Hoenig, M.; Schuetz, C.; Furlan, I.; Beer, M.; von Harsdorf, S.; Bunjes, D.; Debatin, K. M.; Schulz, A. S.
Blood Advances 3(6):862-868, 2019
Expansion of somatically reverted memory CD8+ T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus
Palendira, U.; Low, C.; Bell, A. I.; Ma, C. S.; Abbott, R. J.; Phan, T. G.; Riminton, D. S.; Choo, S.; Smart, J. M.; Lougaris, V.; Giliani, S.; Buckley, R. H.; Grimbacher, B.; Alvaro, F.; Klion, A. D.; Nichols, K. E.; Adelstein, S.; Rickinson, A. B.; Tangye, S. G.
JOURNAL OF EXPERIMENTAL MEDICINE 209(5):913-24, 2012
The expansion of human T-bet(high)CD21(low) B cells is T cell dependent
Keller, B.; Strohmeier, V.; Harder, I.; Unger, S.; Payne, K. J.; Andrieux, G.; Boerries, M.; Felixberger, P. T.; Landry, J. J. M.; Nieters, A.; Rensing-Ehl, A.; Salzer, U.; Frede, N.; Usadel, S.; Elling, R.; Speckmann, C.; Hainmann, I.; Ralph, E.; Gilmour, K.; Wentink, M. W. J.; van der Burg, M.; Kuehn, H. S.; Rosenzweig, S. D.; Kolsch, U.; von Bernuth, H.; Kaiser-Labusch, P.; Gothe, F.; Hambleton, S.; Vlagea, A. D.; Garcia Garcia, A.; Alsina, L.; Markelj, G.; Avcin, T.; Vasconcelos, J.; Guedes, M.; Ding, J. Y.; Ku, C. L.; Shadur, B.; Avery, D. T.; Venhoff, N.; Thiel, J.; Becker, H.; Erazo-Borras, L.; Trujillo-Vargas, C. M.; Franco, J. L.; Fieschi, C.; Okada, S.; Gray, P. E.; Uzel, G.; Casanova, J. L.; Fliegauf, M.; Grimbacher, B.; Eibel, H.; Ehl, S.; Voll, R. E.; Rizzi, M.; Stepensky, P.; Benes, V.; Ma, C. S.; Bossen, C.; Tangye, S. G.; Warnatz, K.
Science Immunology 6(64):eabh0891, 2021
Insights into the role of STAT3 in human lymphocyte differentiation as revealed by the hyper-IgE syndrome
Tangye, S. G.; Cook, M. C.; Fulcher, D. A.;
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Primary immunodeficiencies reveal the molecular requirements for effective host defense against EBV infection.
Tangye, S.G.; Latour, S.
BLOOD 135(9):644-655, 2020
Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency
Kong, X. F.; Martinez-Barricarte, R.; Kennedy, J.; Mele, F.; Lazarov, T.; Deenick, E. K.; Ma, C. S.; Breton, G.; Lucero, K. B.; Langlais, D.; Bousfiha, A.; Aytekin, C.; Markle, J.; Trouillet, C.; Jabot-Hanin, F.; Arlehamn, C. S. L.; Rao, G.; Picard, C.; Lasseau, T.; Latorre, D.; Hambleton, S.; Deswarte, C.; Itan, Y.; Abarca, K.; Moraes-Vasconcelos, D.; Ailal, F.; Ikinciogullari, A.; Dogu, F.; Benhsaien, I.; Sette, A.; Abel, L.; Boisson-Dupuis, S.; Schroder, B.; Nussenzweig, M. C.; Liu, K.; Geissmann, F.; Tangye, S. G.; Gros, P.; Sallusto, F.; Bustamante, J.; Casanova, J. L.
NATURE IMMUNOLOGY 19(9):973-985, 2018
Is it dead or alive? TLR8 can tell
Tangye, S. G.
NATURE IMMUNOLOGY 19(4):324-326, 2018
DOCK8 Drives Src-Dependent NK Cell Effector Function
Kearney, C. J.; Vervoort, S. J.; Ramsbottom, K. M.; Freeman, A. J.; Michie, J.; Peake, J.; Casanova, J. L.; Picard, C.; Tangye, S. G.; Ma, C. S.; Johnstone, R. W.; Randall, K. L.; Oliaro, J.
JOURNAL OF IMMUNOLOGY 199(6):2118-2127, 2017