Molecular Genetics of Inherited Kidney Disorders Lab

Publications

The mouse relaxin gene: nucleotide sequence and expression

Evans, B. A.;John, M.;Fowler, K. J.;Summers, R. J.;Cronk, M.;Shine, J.;Tregear, G. W. :

JOURNAL OF MOLECULAR ENDOCRINOLOGY 10(1):15-23, 1993

Exclusion of close linkage of bipolar disorder to the dopamine D3 receptor gene in nine Australian pedigrees

Mitchell, P.;Waters, B.;Vivero, C.;Le, F.;Donald, J.;Tully, M.;Campedelli, K.;Lannfelt, L.;Sokoloff, P.;Shine, J.;et al. :

JOURNAL OF AFFECTIVE DISORDERS 27(4):213-24, 1993

Progestin regulation of estrogen receptor messenger RNA in human breast cancer cells

Alexander, I. E.;Shine, J.;Sutherland, R. L. :

MOLECULAR ENDOCRINOLOGY 4(6):821-8, 1990

Structural subtypes of the dopamine D2 receptor are functionally distinct: expression of the cloned D2A and D2B subtypes in a heterologous cell line

Hayes, G.;Biden, T. J.;Selbie, L. A.;Shine, J. :

MOLECULAR ENDOCRINOLOGY 6(6):920-6, 1992

Pre- and postjunctional actions of neuropeptide Y and related peptides

Potter, E. K.;Mitchell, L.;McCloskey, M. J.;Tseng, A.;Goodman, A. E.;Shine, J.;McCloskey, D. I. :

Regul Pept 25(2):167-77, 1989

The major dopamine D2 receptor: molecular analysis of the human D2A subtype

Selbie, L. A.;Hayes, G.;Shine, J. :

DNA 8(9):683-9, 1989

Molecular cloning and characterisation of a human brain A1 adenosine receptor cDNA

Townsend-Nicholson, A.;Shine, J. :

Brain Res Mol Brain Res 16(3-4):365-70, 1992

Dopamine receptor diversity

Hayes, G.;Shine, J. :

Todays Life Sciences 4, #11:16-22, 1992

Characterization of the human brain putative A2B adenosine receptor expressed in Chinese hamster ovary (CHO.A2B4) cells

Alexander, S. P.;Cooper, J.;Shine, J.;Hill, S. J. :

BRITISH JOURNAL OF PHARMACOLOGY 119(6):1286-90, 1996

Exclusion of close linkage of bipolar disorder to the Gs-alpha subunit gene in nine Australian pedigrees

Le, F.;Mitchell, P.;Vivero, C.;Waters, B.;Donald, J.;Selbie, L. A.;Shine, J.;Schofield, P. :

JOURNAL OF AFFECTIVE DISORDERS 32(3):187-95, 1994

Molecular cloning and characterisation of the mouse preprogalanin gene

Kofler, B.;Liu, M. L.;Jacoby, A. S.;Shine, J.;Iismaa, T. P. :

GENE 182(1-2):71-5, 1996

Antagonism of ligand-gated ion channel receptors: two domains of the glycine receptor alpha subunit form the strychnine-binding site

Vandenberg, R. J.;French, C. R.;Barry, P. H.;Shine, J.;Schofield, P. R. :

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(5):1765-9, 1992

Assignment of the gene encoding human galanin receptor (GALNR) to 18q23 by in situ hybridization

Nicholl, J.;Kofler, B.;Sutherland, G. R.;Shine, J.;Iismaa, T. P. :

GENOMICS 30(3):629-30, 1995

Home-grown biopharmaceuticals come of age

Shine, J. :

Todays Life Science 6:12-14, 1994

1,25-Dihydroxyvitamin D3 and glucocorticoid regulation of the human osteocalcin gene

Morrison, N.; Shine, J.; Eisman, J.; DV, C.; FH, G.; TJ, M.

Calcium Regulation & Bone Metabolism 10:157-162, 1990

Structural and functional analysis of nitrogenase genes from the broad-host-range Rhizobium strain ANU240

Badenoch-Jones, J.;Holton, T. A.;Morrison, C. M.;Scott, K. F.;Shine, J. :

GENE 77(1):141-53, 1989

High expression in mammalian cells without amplification

Friedman, J. S.;Cofer, C. L.;Anderson, C. L.;Kushner, J. A.;Gray, P.;Chapman, G. E.;Stuart, M. C.;Lazarus, L.;Shine, J.;Kushner, P. J. :

Biotechnology 7 (4):359-362, 1989

Distribution and characterization of the cell types expressing GALR2 mRNA in brain and pituitary gland

Depczynski, B.;Nichol, K.;Fathi, Z.;Iismaa, T.;Shine, J.;Cunningham, A. :

Annals of the New York Academy of Sciences 863:120-8, 1998

The second galanin receptor GalR2 plays a key role in neurite outgrowth from adult sensory neurons

Mahoney, S. A.;Hosking, R.;Farrant, S.;Holmes, F. E.;Jacoby, A. S.;Shine, J.;Iismaa, T. P.;Scott, M. K.;Schmidt, R.;Wynick, D. :

JOURNAL OF NEUROSCIENCE 23(2):416-21, 2003

Human growth hormone production from a recombinant mammalian cell line

Chapman, G. E.;Lazarus, L.;Shine, J.;Kushner, P.;Gray, P. P.;Marsden, W. L. :

Proc Biochemical Processing: New developments and future opportunities, NZ 1987

Effects of human, rat and porcine galanins on cardiac vagal action and blood pressure in the anaesthetised cat

Ulman, L. G.;Evans, H. F.;Iismaa, T. P.;Potter, E. K.;McCloskey, D. I.;Shine, J. :

NEUROSCIENCE LETTERS 136(1):105-8, 1992

Galanin GAL-R1 receptor null mutant mice display increased anxiety-like behavior specific to the elevated plus-maze

Holmes, A.;Kinney, J. W.;Wrenn, C. C.;Li, Q.;Yang, R. J.;Ma, L.;Vishwanath, J.;Saavedra, M. C.;Innerfield, C. E.;Jacoby, A. S.;Shine, J.;Iismaa, T. P.;Crawley, J. N. :

BIOLOGICAL PSYCHIATRY 28(6):1031-44, 2003

Localisation of mRNA encoding the protein precursor of galanin in the monkey hypothalamus and basal forebrain

Evans, H. F.;Huntley, G. W.;Morrison, J. H.;Shine, J. :

JOURNAL OF COMPARATIVE NEUROLOGY 328(2):203-12, 1993

DNA homology screening: isolation and characterization of the human D2A dopamine receptor subtype

Selbie, L. A.;Hayes, G.;Shine, J. :

Adv Second Messenger Phosphoprotein Res 24:9-14, 1990

Molecular biology of the vitamin D hormone

Haussler, M.;Mangelsdorf, D.;Komm, B.;Terpening, C.;Yamaoka, K.;Allegretto, E.;Baker, A.;Shine, J.;McDonnell, D.;Hughes, M.;Weigel, N.;O'Malley, B.;Pike, J. :

RECENT PROG HORM RES 44:263-305, 1988

Hyperalgesia and increased neuropathic pain-like response in mice lacking galanin receptor 1 receptors

Blakeman, K. H.;Hao, J. X.;Xu, X. J.;Jacoby, A. S.;Shine, J.;Crawley, J. N.;Iismaa, T.;Wiesenfeld-Hallin, Z. :

NEUROSCIENCE 117(1):221-7, 2003

Genetic instability and the development of steroid hormone insensitivity in cultured T 47D human breast cancer cells

Reddel, R. R.;Alexander, I. E.;Koga, M.;Shine, J.;Sutherland, R. L. :

CANCER RESEARCH 48(15):4340-7, 1988

Human Sec63 endoplasmic reticulum membrane protein, map position 6q21

Woollatt, E.;Pine, K. A.;Shine, J.;Sutherland, G. R.;Iismaa, T. P. :

CHROMOSOME RESEARCH 7(1):77, 1999

Molecular cloning and expression of an adenosine A2b receptor from human brain

Pierce, K. D.;Furlong, T. J.;Selbie, L. A.;Shine, J. :

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 187(1):86-93, 1992

Steroid hormone receptor gene expression in human breast cancer cells: inverse relationship between oestrogen and glucocorticoid receptor messenger RNA levels

Hall, R. E.;Lee, C. S.;Alexander, I. E.;Shine, J.;Clarke, C. L.;Sutherland, R. L. :

INTERNATIONAL JOURNAL OF CANCER 46(6):1081-7, 1990

Probing the future: hormones affecting blood pressure

Shine, J. :

Clin Biochem Revs 10:13-16, 1989

Molecular modelling and site-directed mutagenesis of human GALR1 galanin receptor defines determinants of receptor subtype specificity

Church, W. B.;Jones, K. A.;Kuiper, D. A.;Shine, J.;Iismaa, T. P. :

Protein Eng 15(4):313-23, 2002

Molecular characterization of a human brain adenosine A2 receptor

Furlong, T. J.;Pierce, K. D.;Selbie, L. A.;Shine, J. :

Brain Res Mol Brain Res 15(1-2):62-6, 1992

Inverse relationship between estrogen receptor and epidermal growth factor receptor mRNA levels in human breast cancer cell lines

Lee, C. S.;Hall, R. E.;Alexander, I. E.;Koga, M.;Shine, J.;Sutherland, R. L. :

GROWTH FACTORS 3(2):97-103, 1990

Structural organization and chromosomal localization of three human galanin receptor genes

Iismaa, T. P.;Fathi, Z.;Hort, Y. J.;Iben, L. G.;Dutton, J. L.;Baker, E.;Sutherland, G. R.;Shine, J. :

Annals of the New York Academy of Sciences 863:56-63, 1998

Galanin and galanin receptors

Iismaa, T. P.;Shine, J. :

Results Probl Cell Differ 26:257-91, 1999

Novel G protein-coupled receptors: a gene family of putative human olfactory receptor sequences

Selbie, L. A.;Townsend-Nicholson, A.;Iismaa, T. P.;Shine, J. :

Brain Res Mol Brain Res 13(1-2):159-63, 1992

Expression of galanin and the GALR1 galanin receptor subtype in the colon of children with paradoxical fecal incontinence

Engelis, A.;Mozgis, D. Z.;Pine, K. A.;Shine, J.;Iismaa, T. P.;Pilmane, M. :

Annals of the New York Academy of Sciences 863:425-9, 1998

G protein-coupled receptors

Iismaa, T. P.;Biden, T. J.;Shine, J. :

JOURNAL OF CARDIAC FAILURE :pp181, 1995

Human galanin: molecular cloning reveals a unique structure

Evans, H. F.;Shine, J. :

ENDOCRINOLOGY 129(3):1682-4, 1991

Human GALR1 galanin receptor (GALNR1). Map position 18q23

Crawford, J.;Hort, Y. J.;Shine, J.;Iismaa, T. P. :

CHROMOSOME RESEARCH 7(3):243, 1999

Exclusion of close linkage of bipolar disorder to dopamine D1 and D2 receptor gene markers

Mitchell, P.;Selbie, L.;Waters, B.;Donald, J.;Vivero, C.;Tully, M.;Shine, J. :

JOURNAL OF AFFECTIVE DISORDERS 25(1):1-11, 1992

A polymorphism in the 3' region of the human preprogalanin gene

Kofler, B.;Lapsys, N.;Furler, S. M.;Klaus, C.;Shine, J.;Iismaa, T. P. :

Mol Cell Probes 12(6):431-2, 1998

The Garvan Institute of Medical Research. Setting the agenda for medical research into the 21st century

Shine, J. :

MEDICAL JOURNAL OF AUSTRALIA 165(11-12):649-51, 1996

Neuropeptide Y and peptide YY have distinct roles in adult mouse olfactory neurogenesis

Doyle, K. L.; Hort, Y. J.; Herzog, H.; Shine, J.;

JOURNAL OF NEUROSCIENCE RESEARCH 90(6):1126-35, 2012

Clinical spectrum, prognosis and estimated prevalence of DNAJB11-kidney disease

Huynh, V. T.; Audrezet, M. P.; Sayer, J. A.; Ong, A. C.; Lefevre, S.; Le Brun, V.; Despres, A.; Senum, S. R.; Chebib, F. T.; Barroso-Gil, M.; Patel, C.; Mallett, A. J.; Goel, H.; Mallawaarachchi, A. C.; Van Eerde, A. M.; Ponlot, E.; Kribs, M.; Genkyst Study Group, Genomics England Research Consortium; Le Meur, Y.; Harris, P. C.; Cornec-Le Gall, E.

KIDNEY INTERNATIONAL 98(2):476-487, 2020

Activity of centrally truncated analogues of neuropeptide Y at Y1 and Y2 receptor subtypes in vivo

McCloskey, M. J.;Moriarty, M. J.;Tseng, A.;Shine, J.;Potter, E. K. :

NEUROPEPTIDES 31(2):193-7, 1997

Altered hippocampal expression of neuropeptides in seizure-prone GALR1 knockout mice

Fetissov, S. O.;Jacoby, A. S.;Brumovsky, P. R.;Shine, J.;Iismaa, T. P.;Hokfelt, T. :

EPILEPSIA 44(8):1022-33, 2003

Close linkage of bipolar disorder to chromosome 11 markers is excluded in two large Australian pedigrees

Mitchell, P.;Waters, B.;Morrison, N.;Shine, J.;Donald, J.;Eisman, J. :

JOURNAL OF AFFECTIVE DISORDERS 21(1):23-32, 1991

Critical role for GALR1 galanin receptor in galanin regulation of neuroendocrine function and seizure activity

Jacoby, A. S.;Hort, Y. J.;Constantinescu, G.;Shine, J.;Iismaa, T. P. :

Brain Res Mol Brain Res 107(2):195-200, 2002

Localization of preprogalanin mRNA in the monkey hippocampal formation

Evans, H. F.;Huntley, G. W.;Morrison, J. H.;Shine, J.;Paxinos, G. :

NEUROSCIENCE LETTERS 146(2):171-5, 1992

G protein-coupled receptors

Iismaa, T. P.;Shine, J. :

CURRENT OPINION IN CELL BIOLOGY 4(2):195-202, 1992

Comprehensive evaluation of a prospective Australian patient cohort with suspected genetic kidney disease undergoing clinical genomic testing: a study protocol

Jayasinghe, K.; Stark, Z.; Patel, C.; Mallawaarachchi, A.; McCarthy, H.; Faull, R.; Chakera, A.; Sundaram, M.; Jose, M.; Kerr, P.; Wu, Y.; Wardrop, L.; Goranitis, I.; Best, S.; Martyn, M.; Quinlan, C.; Mallett, A. J.

BMJ Open 9(8):e029541, 2019

Attitudes and Practices of Australian Nephrologists Toward Implementation of Clinical Genomics

Jayasinghe, K.; Quinlan, C.; Mallett, A. J.; Kerr, P. G.; McClaren, B.; Nisselle, A.; Mallawaarachchi, A.; Polkinghorne, K. R.; Patel, C.; Best, S.; Stark, Z.

Kidney International Reports 6(2):272-283, 2021

Phenotypic analysis of Galr1 knockout mice reveals a role for GALR1 galanin receptor in modulating seizure activity but not nerve regeneration

Jacoby, A. S.;Holmes, F. E.;Hort, Y. J.;Shine, J.;Iismaa, T. P. :

Lett Pept Sci 8:139-146, 2002

Structural conservation and functional diversity--profile of a political peptide

Shine, J. :

ENDOCRINOLOGY 134(5):1989-90, 1994

1,25-dihydroxyvitamin D-responsive element and glucocorticoid repression in the osteocalcin gene

Morrison, N. A.;Shine, J.;Fragonas, J. C.;Verkest, V.;McMenemy, M. L.;Eisman, J. A. :

SCIENCE 246(4934):1158-61, 1989

A polymorphism in the human GALR3 galanin receptor gene (GALNR3)

Lapsys, N. M.;Furler, S. M.;Henderson, N. K.;Dutton, J. L.;Hort, Y. J.;Eisman, J. A.;Shine, J.;Iismaa, T. P. :

Mol Cell Probes 13(4):325-7, 1999

Structural organization of the mouse and human GALR1 galanin receptor genes (Galnr and GALNR) and chromosomal localization of the mouse gene

Jacoby, A. S.;Webb, G. C.;Liu, M. L.;Kofler, B.;Hort, Y. J.;Fathi, Z.;Bottema, C. D.;Shine, J.;Iismaa, T. P. :

GENOMICS 45(3):496-508, 1997

A mutation affecting laminin alpha 5 polymerisation gives rise to a syndromic developmental disorder

Jones, L. K.; Lam, R.; McKee, K. K.; Aleksandrova, M.; Dowling, J.; Alexander, S. I.; Mallawaarachchi, A.; Cottle, D. L.; Short, K. M.; Pais, L.; Miner, J. H.; Mallett, A. J.; Simons, C.; McCarthy, H.; Yurchenco, P. D.; Smyth, I. M.

DEVELOPMENT 147(21) 2020

Dependence of hypotensive effect of neuropeptide-Y 18-36 fragment on intact vagus nerves

Potter, E. K.;Persico, M.;Mitchell, L.;de Pietra, M. G.;Loughnan, M.;Shine, J.;McCloskey, D. I. :

J Auton Nerv Syst 37(3):155-62, 1992

Biosynthetic human growth hormone production using a mammalian cell line

Lazarus, L.;Gray, P.;Shine, J.;Chapman, G.;Stuart, M.;Kushner, P.;Marsden, W. :

The World Biotechnology Report 1985 3: As:109-, 1985

The use of a mammalian cell line to produce biosynthetic human growth hormone

Gray, P.;Lazarus, L.;Chapman, G.;Shine, J.;Kushner, P.;Marsden, W.;Panowitz, D.;Crowley, J. :

J Proc 7th Aust Biotech Conf :106-111, 1986

Isolation and chromosomal localization of a novel human G-protein-coupled receptor (GPR3) expressed predominantly in the central nervous system

Iismaa, T. P.;Kiefer, J.;Liu, M. L.;Baker, E.;Sutherland, G. R.;Shine, J. :

GENOMICS 24(2):391-4, 1994

Progestin inhibition of progesterone receptor gene expression in human breast cancer cells

Alexander, I. E.;Clarke, C. L.;Shine, J.;Sutherland, R. L. :

MOLECULAR ENDOCRINOLOGY 3(9):1377-86, 1989

Genomic diagnostics in polycystic kidney disease: an assessment of real-world use of whole-genome sequencing

Mallawaarachchi, A. C.; Lundie, B.; Hort, Y.; Schonrock, N.; Senum, S. R.; Gayevskiy, V.; Minoche, A. E.; Hollway, G.; Ohnesorg, T.; Hinchcliffe, M.; Patel, C.; Tchan, M.; Mallett, A.; Dinger, M. E.; Rangan, G.; Cowley, M. J.; Harris, P. C.; Burnett, L.; Shine, J.; Furlong, T. J.

EUROPEAN JOURNAL OF HUMAN GENETICS 29(5):760-770, 2021

Cloning and expression of full-length cDNA encoding human vitamin D receptor

Baker, A. R.;McDonnell, D. P.;Hughes, M.;Crisp, T. M.;Mangelsdorf, D. J.;Haussler, M. R.;Pike, J. W.;Shine, J.;O'Malley, B. W. :

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 85(10):3294-8, 1988

High density lipoproteins, genetic polymorphism for apo A-I and coronary artery disease

Simons, L. A.;Balasubramaniam, S.;Szanto, A.;Simons, J.;Friedlander, Y.;Hickie, J. B.;Shine, J. :

Aust N Z J Med 21(3):330-4, 1991