Insulin Signalling Lab


Protein kinase Cepsilon modulates insulin receptor localization and trafficking in mouse embryonic fibroblasts
Pedersen, D. J.; Diakanastasis, B. ; Stockli, J. ; Schmitz-Peiffer, C.;
PLoS One 8(3):e58046, 2013
Time-dependent effects of Prkce deletion on glucose homeostasis and hepatic lipid metabolism on dietary lipid oversupply in mice
Raddatz, K.; Turner, N.; Frangioudakis, G.; Liao, B. M.; Pedersen, D. J.; Cantley, J.; Wilks, D.; Preston, E.; Hegarty, B. D.; Leitges, M.; Raftery, M. J.; Biden, T. J.; Schmitz-Peiffer, C.
DIABETOLOGIA 54(6):1447-56, 2011
Deconstructing the Role of PKC Epsilon in Glucose Homeostasis
Schmitz-Peiffer, C.
Deletion of protein kinase Cepsilon in mice has limited effects on liver metabolite levels but alters fasting ketogenesis and gluconeogenesis
Raddatz, K.; Frangioudakis, G.; Diakanastasis, B.; Liao, B. M.; Leitges, M.; Schmitz-Peiffer, C.
DIABETOLOGIA 55(10):2789-93, 2012
Targeting ceramide synthesis to reverse insulin resistance
Schmitz-Peiffer, C.;
DIABETES 59(10):2351-3, 2010
PKCdelta blues for the beta-cell
Schmitz-Peiffer, C.; Biden, T. J.;
DIABETES 59(1):1-3, 2010
Proteomic analysis of livers from fat-fed mice deficient in either PKCdelta or PKCepsilon identifies Htatip2 as a regulator of lipid metabolism
Liao, B. M.
; Raddatz, K.
; Zhong, L.
; Parker, B. L.
; Raftery, M. J.
; Schmitz-Peiffer, C.;
PROTEOMICS 14(21-22):2578-87, 2014
Protein Kinase C Epsilon Deletion in Adipose Tissue, but Not in Liver, Improves Glucose Tolerance
Brandon, A. E.; Liao, B. M.; Diakanastasis, B.; Parker, B. L.; Raddatz, K.; McManus, S. A.; O'Reilly, L.; Kimber, E.; van der Kraan, A. G.; Hancock, D.; Henstridge, D. C.; Meikle, P. J.; Cooney, G. J.; James, D. E.; Reibe, S.; Febbraio, M. A.; Biden, T. J.; Schmitz-Peiffer, C.
Cell Metabolism 29(1):183-191 e7, 2019
Characterization of peptide interactions that regulate PKCε activation
Chandrashekaran, I. R., Norton, R. S., Schmitz-Peiffer, C.
FEBS LETTERS 592(2):179-189, 2018
Anarchy in the UPR: A Ca(2+)-insensitive PKC inhibits SERCA activity to promote ER stress
Schmitz-Peiffer, C.
BIOSCIENCE REPORTS :pii: BSR20170966, 2018
A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism
Turner, N.; Lim, X. Y.; Toop, H. D.; Osborne, B.; Brandon, A. E.; Taylor, E. N.; Fiveash, C. E.; Govindaraju, H.; Teo, J. D.; McEwen, H. P.; Couttas, T. A.; Butler, S. M.; Das, A.; Kowalski, G. M.; Bruce, C. R.; Hoehn, K. L.; Fath, T.; Schmitz-Peiffer, C.; Cooney, G. J.; Montgomery, M. K.; Morris, J. C.; Don, A. S.
Nature Communications 9(1):3165, 2018