Selected Publications
Colinda L. G. J. Scheele*, David Herrmann*, Erika Yamashita, Cristina Lo Celso, Craig N. Jenne, Maja H. Oktay, David Entenberg, Peter Friedl, Roberto Weigert, Franck L. B. Meijboom, Masaru Ishii, Paul Timpson#, and Jacco van Rheenen# (2022). Multiphoton intravital microscopy of rodents. Nature Reviews Methods Primers 2(1), 89. *Co-first author, #Co-corresponding author.
Michael Papanicolaou, Amelia L. Parker, Michelle Yam, Elysse C. Filipe, Sunny Z. Wu, Jessica L. Chitty, Kaitlin Wyllie, Emmi Tran, Ellie Mok, Audrey Nadalini, Joanna N. Skhinas, Morghan C. Lucas, David Herrmann, Max Nobis, Brooke A. Pereira, Andrew M. K. Law, Lesley Castillo, Kendelle J. Murphy, Anaiis Zaratzian, Jordan F. Hastings, David R. Croucher, Elgene Lim, Brian G. Oliver, Fatima Valdes Mora, Benjamin L. Parker, David Gallego-Ortega, Alexander Swarbrick, Sandra O’Toole, Paul Timpson#, and Thomas R. Cox# (2022) Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis. Nature Communications. 13, 4587. #Co-corresponding author.
Kendelle J. Murphy, Daniel A. Reed, Claire Vennin, James R. W. Conway, Max Nobis, Julia X. Yin, Cecilia R. Chambers, Brooke A. Pereira, Victoria Lee, Elysse C. Filipe, Michael Trpceski, Shona Ritchie, Morghan C. Lucas, Sean C. Warren, Joanna N. Skhinas, Astrid Magenau, Xanthe L. Metcalf, Janett Stoehr, Gretel Major, Ashleigh Parkin, Romain Bidanel, Ruth J. Lyons, Anaiis Zaratzian, Michael Tayao, Andrew Da Silva, Lea Abdulkhalek, Australian Pancreatic Genome Initiative (APGI), Australian Pancreatic Cancer Matrix Atlas (APMA), Anthony J. Gill, Amber L. Johns, Andrew V. Biankin, Jaswinder Samra, Sean M. Grimmond, Angela Chou, Jacky G. Goetz, Michael S. Samuel, J. Guy Lyons, Andrew Burgess, C. Elizabeth Caldon, Lisa G. Horvath, Roger J. Daly, Nikolaj Gadegaard, Yingxiao Wang, Owen J. Sansom, Jennifer P. Morton, Thomas R. Cox, Marina Pajic, David Herrmann#, and Paul Timpson# (2021) Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status. Science Advances. 7(40), eabh0363. #Co-corresponding author.
Alessia Floerchinger, Kendelle J. Murphy, Sharissa L. Latham, Sean C. Warren, Andrew T. McCulloch, Young-Kyung Lee, Janett Stoehr, Pauline Mélénec, Cris S. Guaman, Xanthe L. Metcalf, Victoria Lee, Anaiis Zaratzian, Andrew Da Silva, Michael Tayao, Sonia Rolo, Monica Phimmachanh, Ghazal Sultani, Laura McDonald, Susan M. Mason, Nicola Ferrari, Lisa M. Ooms, Anna-Karin E. Johnsson, Heather J. Spence, Michael F. Olson, Laura M. Machesky, Owen J. Sansom, Jennifer P. Morton, Christina A. Mitchell, Michael S. Samuel, David R. Croucher, Heidi C.E. Welch, Karen Blyth, C. Elizabeth Caldon, David Herrmann, Kurt I. Anderson, Paul Timpson#, Max Nobis# (2021) Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging. Cell Reports. 36(11),109689. #Co-corresponding author.
Quantifying and visualising the nuances of cellular dynamics in vivo using intravital imaging. Current Opinion in Cell Biology. 72, 41-53. #Co-corresponding author.
Cecilia R. Chambers, Shona Ritchie, Brooke A. Pereira#, Paul Timpson# (2021) Overcoming the senescence-associated secretory phenotype (SASP): a complex mechanism of resistance in the treatment of cancer. Molecular Oncology. doi: 10.1002/1878-0261.13042. #Co-corresponding author.
Shona Ritchie, Daniel A. Reed, Brooke A. Pereira#, Paul Timpson# (2021) The cancer cell secretome drives cooperative manipulation of the tumour microenvironment to accelerate tumourigenesis. Faculty Reviews. 10, 4. doi: 10.12703/r/10-4. #Co-corresponding author.
Follain G, Herrmann D, Harlepp S, Hyenne V, Osmani N, Warren SC, Timpson P#, Goetz JG# (2020) Fluids and their mechanics in tumour transit: shaping metastasis. Nature Reviews Cancer. 20(2):107-124.
Shona C. Ritchie, Brooke A. Pereira, Claire Vennin#, Paul Timpson# (2020) Targeting genetically-tuned CAFs in pancreatic cancer via perlecan manipulation. Expert Opinion on Therapeutic Targets. 24(3), 171-174. #Co-corresponding author.
Brooke A. Pereira, Claire Vennin, Michael Papanicolaou, Cecilia R. Chambers, David Herrmann, Jennifer P. Morton, Thomas R. Cox# and Paul Timpson# (2019) CAF subpopulations: a new reservoir of stromal targets in pancreatic cancer. Trends in Cancer. 5 (11), 724-741. #Co-corresponding author.
Claire Vennin, Pauline Mélénec, Romain Rouet, Kendelle J. Murphy, David Herrmann, Daniel A. Reed, Morghan C. Lucas, Sean C. Warren, Zehra Elgundi, Mark Pinese, Gabriella Kalna, Daniel Roden, Monisha Samuel, Anaiis Zaratzian, Shane T. Grey, Andrew Da Silva, Wilfred Leung, Australian Pancreatic Genome Initiative (APGI), Suresh Mathivanan, Yingxiao Wang, Anthony W. Braithwaite, Daniel Christ, Ales Benda, Ashleigh Parkin, Phoebe A. Phillips, John M. Whitelock, Anthony J. Gill, Owen J. Sansom, David R. Croucher, Benjamin L. Parker, Marina Pajic, Jennifer P. Morton, Thomas R. Cox# & Paul Timpson# (2019) CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan. Nature Communications. 10(1), 3637. #Co-corresponding author.
Neophytos Christodoulou, Antonia Weberling, Douglas Strathdee, Kurt I. Anderson, Paul Timpson & Magdalena Zernicka-Goetz (2019) Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation. Nature Communications. 10(1), 3557.
Ashleigh Parkin, Jennifer Man, Paul Timpson#, and Marina Pajic# (2019) Targeting the complexity of Src signalling in the tumour microenvironment of pancreatic cancer: from mechanism to therapy. The FEBS Journal. doi:10.1111/febs.15011. #Co-corresponding authors
James R.W. Conway, David Herrmann, Jeffry Evans, Jennifer P. Morton and Paul Timpson (2019) Combating pancreatic cancer with PI3K pathway inhibitors in the era of personalized medicine.
Andreia V. Pinho, Mathias Van Bulck, Lorraine Chantrill, Mehreen Arshi, Tatyana Sklyarova, David Herrmann, Claire Vennin, David Gallego-Ortega, Amanda Mawson, Marc Giry-Laterriere, Astrid Magenau, Luc Baeyens, Australian Pancreatic Cancer Genome Initiative (APGI), Anthony J. Gill, Phoebe Phillips, Paul Timpson, Andrew Biankin, Jianmin Wu, Ilse Rooman (2018) ROBO2 is a stroma suppressor gene in the pancreas through regulation of TGF-b. Nature Communications, 9(1): 5083.
Sean C. Warren #, Max Nobis, Astrid Magenau, Yousuf H. Mohammed, David Herrmann, Imogen Moran, Claire Vennin, James R.W. Conway, Pauline Mélénec, Yingxiao Wang, Jennifer P. Morton, Heidi C.E. Welch, Douglas Strathdee, Kurt I. Anderson, Tri G. Phan, Michael S. Roberts and Paul Timpson # (2018) Removing physiological motion from intravital and clinical fluorescence imaging data. eLife. 7, e35800. doi:10.7554/eLife.35800. #Co-corresponding authors
James R.W. Conway, Sean C. Warren, David Herrmann, Kendelle J. Murphy, Aurélie S. Cazet, Claire Vennin, Robert F. Shearer, Monica J. Killen, Astrid Magenau, Pauline Mélénec, Mark Pinese, Max Nobis, Anaiis Zaratzian, Alice Boulghourjian, Andrew M. Da Silva, Gonzalo del Monte-Nieto, Arne S.A. Adam, Richard P. Harvey, Jody J. Haigh, Yingxiao Wang, David R. Croucher, Owen J. Sansom, Marina Pajic, C. Elizabeth Caldon, Jennifer P. Morton# and Paul Timpson# (2018) Intravital imaging to monitor therapeutic response in moving hypoxic regions resistant to PI3K pathway targeting in pancreatic cancer. Cell Reports. 23(11): 3312-3326. #Co-corresponding authors
Nicola Rath, June Munro, Marie Francene Cutiongco, Alicja Jagiełło, Nikolaj Gadegaard, Lynn McGarry, Mathieu Unbekandt, Evdokia Michalopoulou, Jurre J. Kamphorst, David Sumpton, Gillian Mackay, Claire Vennin, Marina Pajic, Paul Timpson, Michael F Olson (2018) Rho kinase inhibitor AT13148 blocks pancreatic ductal adenocarinoma invasion and tumor growth. Cancer Research. doi: 10.1158/0008-5472.CAN-17-1339.
Max Nobis, Sean C. Warren, Morghan C. Lucas, Kendelle J. Murphy, David Herrmann# and Paul Timpson# (2018) Molecular mobility and activity in an intravital imaging setting - implications for cancer progression and targeting. Journal of Cell Science. 131(5). pii: jcs206995. doi: 10.1242/jcs.206995. #Co-corresponding authors
Claire Vennin, Kendelle J. Murphy, Jennifer P. Morton, Thomas R. Cox, Marina Pajic# and Paul Timpson# (2018) Reshaping the tumor stroma for treatment of pancreatic cancer. Gastroenterology, Dec 26. doi: 10.1053/j.gastro.2017.11.280. Epub. #Co-corresponding authors
Fahad A. Benthani, David Herrmann, Phuong N. Tran, Laurent Pangon, Morghan C. Lucas, Amr H. Allam, Nicola Currey, Sam Al-Sohaily, Marc Giry-Laterriere, Janindra Warusavitarne, Paul Timpson# and Maija R.J. Kohonen-Corish# (2018) ‘MCC’ protein interacts with E-cadherin and β-catenin strengthening cell–cell adhesion of HCT116 colon cancer cells. Oncogene. doi: 10.1038/onc.2017.362. #Co-corresponding authors
Max Nobis, David Herrmann, Sean C. Warren, Shereen Kadir, Wilfred Leung, Monica Killen, Astrid Magenau, David Stevenson, Morghan C. Lucas, Nadine Reischmann, Claire Vennin, James R.W. Conway, Alice Boulghourjian, Anaiis Zaratzian, Andrew M. Law, David Gallego-Ortega, Christopher J. Ormandy, Stacey N. Walters, Shane T. Grey, Jacqueline Bailey, Tatyana Chtanova, Julian M.W. Quinn, Paul A. Baldock, Peter I. Croucher, Juliane P. Schwarz, Agata Mrowinska, Lei Zhang, Herbert Herzog, Andrius Masedunskas, Edna C. Hardeman, Peter W. Gunning, Gonzalo del Monte-Nieto, Richard P. Harvey, Michael S. Samuel, Marina Pajic, Ewan J. McGhee, Anna-Karin E. Johnsson, Owen J. Sansom, Heidi C.E. Welch, Jennifer P. Morton, Douglas Strathdee, Kurt I. Anderson#, and Paul Timpson# (2017) A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts. Cell Reports. 21(1), 274-288. doi: 10.1016/j.celrep.2017.09.022. #Co-corresponding authors
Claire Vennin, Venessa T. Chin, Sean C. Warren, Morghan C. Lucas, David Herrmann, Astrid Magenau, Pauline Melenec, Stacey N. Walters, Gonzalo del Monte-Nieto, James R.W. Conway, Max Nobis, Amr H. Allam, Rachael A. McCloy, Nicola Currey, Mark Pinese, Alice Boulghourjian, Anaiis Zaratzian, Arne S.A. Adam, Celine Heu, Adnan M. Nagrial, Angela Chou, Angela Steinmann, Alison Drury, Danielle Froio, Marc Giry-Laterriere, Nathanial L.E. Harris, Tri Phan, Rohit Jain, Wolfgang Weninger, Ewan J. McGhee, Renee Whan, Amber L. Johns, Jaswinder S. Samra, Lorraine Chantrill, Anthony J. Gill, Maija Kohonen-Corish, Richard P. Harvey, Andrew V. Biankin, Australian Pancreatic Cancer Genome Initiative (APGI), T.R. Jeffry Evans, Kurt I. Anderson, Shane T. Grey, Christopher J. Ormandy, David Gallego-Ortega, Yingxiao Wang, Michael S. Samuel, Owen J. Sansom, Andrew Burgess, Thomas R. Cox, Jennifer P. Morton, Marina Pajic# and Paul Timpson# (2017) Transient tissue ‘priming’ via ROCK manipulation uncouples pancreatic cancer progression, chemo-resistance and the onset of the metastatic niche. Science Translational Medicine. 9(384). doi: 10.1126/scitranslmed.aai8504. #Co-corresponding authors full text Reprints
James R.W. Conway, Sean C. Warren and Paul Timpson# (2017) Context-dependent intravital imaging of therapeutic response using intramolecular FRET biosensors. Methods. 128, 78-94. doi: 10.1016/j.ymeth.2017.04.014. #Corresponding author
Claire Vennin, David Herrmann, Morghan C. Lucas, Paul Timpson# (2016) Intravital imaging reveals new ancillary mechanisms co-opted by cancer cells to drive tumor progression. F1000Research. 5(F1000 Faculty Rev), 892. #Corresponding author
Zahra Erami, David Herrmann, Sean C. Warren, Max Nobis, Ewan J. McGhee, Morghan C. Lucas, Wilfred Leung, Nadine Reischmann, Agata Mrowinska, Juliane P. Schwarz, Shereen Kadir, James R.W. Conway, Claire Vennin, Saadia A. Karim, Andrew D. Campbell, David Gallego-Ortega, Astrid Magenau, Kendelle J. Murphy, Rachel A. Ridgway, Andrew M. Law, Stacey N. Walters, Shane T. Grey, David R. Croucher, Lei Zhang, Herbert Herzog, Edna C. Hardeman, Peter W. Gunning, Chris J. Ormandy, T.R. Jeffry Evans, Douglas Strathdee, Owen J. Sansom, Jennifer P. Morton, Kurt I. Anderson# and Paul Timpson# (2016) Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue. Cell Reports. 14, 152-67. #Corresponding authors
Jasreen Kular, Kaitlin G. Scheer, Natasha T. Pyne, Amr H. Allam, Anthony N. Pollard, Astrid Magenau, Rebecca L. Wright, Natasha Kolesnikoff, Paul A. Moretti, Lena Wullkopf, Frank C. Stomski, Allison J. Cowin, Joanna M. Woodcock, Michele A. Grimbaldeston, Stuart M. Pitson, Paul Timpson, Hayley S. Ramshaw, Angel F. Lopez, Michael S. Samuel (2015) A Negative Regulatory Mechanism Involving 14-3-3ζ Limits Signaling Downstream of ROCK to Regulate Tissue Stiffness in Epidermal Homeostasis. Developmental Cell. 35(6), 759-74. doi: 10.1016/j.devcel.2015.11.026.
Lisa M. Ooms, Lauren C. Binge, Elizabeth M. Davies, Parvin Rahman, James R.W. Conway, Rajendra Gurung, Daniel T. Ferguson, Antonella Papa, Clare G. Fedele, Jessica L. Vieusseux, Ryan C. Chai, Frank Koentgen, John T. Price, Tony Tiganis, Paul Timpson, Catriona A. McLean and Christina A. Mitchell (2015) The Inositol Polyphosphate 5-Phosphatase PIPP Regulates AKT1-Dependent Breast Cancer Growth and Metastasis. Cancer Cell. 28(2), 155-69. doi: 10.1016/j.ccell.2015.07.003.
James R.W. Conway, Neil O. Carragher# and Paul Timpson# (2014) Developments in preclinical cancer imaging: innovating the discovery of therapeutics. Nature Reviews Cancer. 14, 314-328. #Co-corresponding authors *received a F1000 prime 2-star recommendation.
David Herrmann, James R.W. Conway, Claire Vennin, Astrid Magenau, Will E. Hughes, Jen P. Morton and Paul Timpson# (2014) Three-dimensional cancer models mimic cell-matrix interactions in the tumour microenvironment. Carcinogenesis. #Corresponding author
Anna-Karin E. Johnsson, Yanfeng Dai, Max Nobis, Martin J. Baker, Ewan J. McGhee, Simon Walker, Juliane P. Schwarz, Shereen Kadir, Jennifer P. Morton, Kevin B. Myant, David J. Huels, Anne Segonds-Pichon, Owen J. Sansom, Kurt I. Anderson, Paul Timpson# and Heidi C.E. Welch# (2014) The Rac-FRET Mouse Reveals Tight Spatiotemporal Control of Rac Activity in Primary Cells and Tissues. Cell reports. 6, 1153-1164. #Co-corresponding authors
Meritxell Reverter, Carles Rentero, Ana Garcia-Melero, Monira Hoque, Sandra Vilà de Muga, Anna Álvarez-Guaita, James R.W. Conway, Peta Wood, Rose Cairns, Lilia Lykopoulou, Daniel Grinberg, Lluïsa Vilageliu, Marta Bosch, Joerg Heeren, Juan Blasi, Paul Timpson, Albert Pol, Francesc Tebar, Rachael Z. Murray, Thomas Grewal, Carlos Enrich (2014) Cholesterol Regulates Syntaxin 6 Trafficking at trans-Golgi Network Endosomal Boundaries. Cell reports.
Max Nobis, Neil O. Carragher, Ewan J. McGhee, Jennifer P. Morton, Owen J. Sansom, Kurt I. Anderson and Paul Timpson# (2013) Advanced intravital sub-cellular imaging reveals vital 3D signalling events driving cancer cell behaviour and drug response in live tissue. FEBS Journal. 280(12), 5177-97. #Corresponding author
Max Nobis, Ewan J. McGhee, Jennifer P. Morton, Juliane P. Schwarz, Saadia A. Karim, Jean Quinn, Mike Edward, Andrew D. Campbell, Lynn C. McGarry, T.R. Jeffry Evans, Valerie G. Brunton, Margaret C. Frame, Neil O. Carragher, Yingxiao Wang, Owen J. Sansom, Paul Timpson# and Kurt I. Anderson# (2013) Intravital FLIM-FRET imaging reveals dasatinib-induced spatial control of Src in pancreatic cancer. Cancer Research. 73(15), 4674-86. #Co-corresponding authors
Kevin B. Myant, Patrizia Cammareri, Ewan J. McGhee, Rachel A. Ridgway, David J. Huels, Julia B. Cordero, Sarah Schwitalla, Gabriela Kalna, Erinn-Lee Ogg, Dimitris Athineos, Paul Timpson, Marcos Vidal, Graeme I. Murray, Florian R. Greten, Kurt I. Anderson, Owen J. Sansom (2013) ROS production and NF-kappaB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation. Cell stem cell .12, 761-773.
Paul Timpson#, Ewan J. McGhee, Jennifer P. Morton, Alex von Kriegsheim, Juliane P. Schwarz, Saadia A. Karim, Brendan Doyle, Jean A. Quinn, Neil O. Carragher, Mike Edward, Michael F. Olson, Margaret C. Frame, Valerie G. Brunton, Owen J. Sansom and Kurt I. Anderson (2011) Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53. Cancer Research. 71(3), 747-57. #Corresponding author
Paul Timpson, Ewan J. McGhee and Kurt I. Anderson (2011) Imaging molecular dynamics in vivo--from cell biology to animal models. J Cell Sci. 124, 2877-2890.
Ewan J. McGhee, Jennifer P. Morton, Alex Von Kriegsheim, Juliane P. Schwarz, Saadia A. Karim, Neil O. Carragher, Owen J. Sansom, Kurt I. Anderson and Paul Timpson# (2011) FLIM-FRET Imaging In Vivo Reveals 3D-Environment Spatially Regulates RhoGTPase Activity During Cancer Cell Invasion. Small GTPases. 2(4), 239-244. #Corresponding author
Paul Timpson, Ewan J. McGhee, Zahra Erami, Jean A. Quinn, Mike Edward, and Kurt I. Anderson (2011) Organotypic collagen Ι assay: A malleable platform to assess cell behaviour in a 3-dimensional context. J Vis Exp. (56), e3089.
Colin R. Lindsay, Samuel Lawn, Andrew D. Campbell, William J. Faller, Richard L. Mort, Florian Rambow, Paul Timpson, Ang Li, Rachel A. Ridgway, Jennifer P. Morton, Brendan Doyle, Mairin Rafferty, Ian G. Murphy, Enda W. McDermott, Kieran Sheahan, Katherine Pedone, Alexander J. Finn, Pamela A. Groben, Nancy E. Thomas, Honglin Hao, Craig Carson, William M. Gallacher, Ian J. Jackson, Leon Van Kempen, Channing Der , Friedrich Beermann, Lionel Larue, Heidi C. Welch, Brad W. Ozanne, and Owen J. Sansom (2011) P-Rex1 is required for efficient melanoblast migration and melanoma metastasis. Nature Communications. 2, 555.
Michael Samuel, Jose Lopez, Ewan McGhee, Daniel Croft, David Strachan, Paul Timpson, June Munro, Ewald Schröder, Jing Zhou, Valerie Brunton, Nick Barker, Hans Clevers, Owen Sansom, Kurt Anderson, Valerie Weaver and Michael Olson (2011) Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce interfollicular epidermal hyperplasia and tumor growth. Cancer Cell. 19(6), 776-91.
Jennifer Morton, Paul Timpson, Saadia A. Karim, Rachel A. Ridgway, Dimitris Athineos, Brendan D. Doyle, Nigel B. Jamieson, Karin A. Oien, Andy Lowy, Valerie G. Brunton, Margaret C. Frame, T.R. Jeffry Evans and Owen J. Sansom (2010) Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer. PNAS USA. 107(1), 246-51. *received a F1000 prime 2-star recommendation.
Jennifer Morton, Saadia Karim, Kathryn Graham, Paul Timpson, Nigel Jamieson, Susan Mason, Man-yeung Heung, Karin A. Oien, Margaret C. Frame, T.R. Jeffry Evans, Owen J. Sansom and Valerie G. Brunton (2010) Dasatinib inhibits the development of metastases in a mouse model of pancreatic ductal adenocarcinoma. Gastroenterology. 139 (1), 292-303.
Alan Serrels*, Paul Timpson*, Marta Canel, Juliane P Schwarz, Neil Carragher, Margaret C. Frame, Valerie G. Brunton and Kurt Anderson (2009) Real-time study of E-cadherin and membrane dynamics in living animals; implications for disease modelling and drug development. Cancer Research. 69(7), 2714-9. *co-first authors
Paul Timpson, Ashleigh S. Wilson, Gillian M. Lehrbach, Robert L. Sutherland, Elizabeth A. Musgrove and Roger J. Daly (2007) Aberrant expression of cortactin in head and neck squamous cell carcinoma cells is associated with enhanced cell proliferation and resistance to the epidermal growth factor receptor inhibitor gefitinib. Cancer Research. 67(19), 9304-14.
Paul Timpson, Danielle K. Lynch, Daniel Schramek, Francesca Walker, and Roger J. Daly (2005) Cortactin overexpression inhibits ligand-induced down-regulation of the epidermal growth factor receptor. Cancer Res. 65, 3273-3280.
Paul Timpson, Gareth E. Jones, Margaret C. Frame and Valerie G. Brunton (2001) Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity. Curr Biol. 11, 1836-1846.
More Garvan Publications
