Parkinsons Disease and Neurodegeneration Lab


ERADicate ER Stress or Die Trying
Kincaid, M. M.;Cooper, A. A. :
Common Variants Coregulate Expression of GBA and Modifier Genes to Delay Parkinson's Disease Onset
Schierding, W.; Farrow, S.; Fadason, T.; Graham, O. E. E.; Pitcher, T. L.; Qubisi, S.; Davidson, A. J.; Perry, J. K.; Anderson, T. J.; Kennedy, M. A.; Cooper, A.; O'Sullivan, J. M.
MOVEMENT DISORDERS 35(8):1346-1356, 2020
Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease
Dong, X.; Liao, Z.; Gritsch, D.; Hadzhiev, Y.; Bai, Y.; Locascio, J. J.; Guennewig, B.; Liu, G.; Blauwendraat, C.; Wang, T.; Adler, C. H.; Hedreen, J. C.; Faull, R. L. M.; Frosch, M. P.; Nelson, P. T.; Rizzu, P.; Cooper, A. A.; Heutink, P.; Beach, T. G.; Mattick, J. S.; Muller, F.; Scherzer, C. R.
NATURE NEUROSCIENCE 21(10):1482-1492, 2018
Misfolded proteins traffic from the endoplasmic reticulum (ER) due to ER export signals
Kincaid, M. M.;Cooper, A. A. :
De Novo Gene Variants and Familial Bipolar Disorder
Toma, C.; Shaw, A. D.; Overs, B. J.; Mitchell, P. B.; Schofield, P. R.; Cooper, A. A.; Fullerton, J. M.
JAMA Network Open 3(5):e203382, 2020
alphaSynuclein and Mitochondrial Dysfunction: A Pathogenic Partnership in Parkinson's Disease?
Protter, D.; Lang, C.; Cooper, A. A.;
Parkinson's Disease 2012:829207, 2012
Intronic Haplotypes in GBA Modify Age at Diagnosis of Parkinson's: Replication in a Subgroup
O'Sullivan, J. M.; den Heijer, J. M.; Groeneveld, G. J.; Cooper, A. A.
MOVEMENT DISORDERS 36(6):1468-1470, 2021
Defining early changes in Alzheimer's disease from RNA sequencing of brain regions differentially affected by pathology
Guennewig, B.; Lim, J.; Marshall, L.; McCorkindale, A. N.; Paasila, P. J.; Patrick, E.; Kril, J. J.; Halliday, G. M.; Cooper, A. A.; Sutherland, G. T.
Scientific Reports 11(1):4865, 2021