The microanatomy of B cell activation.
The logistic problem of B cell antigen encounter in the lymph node has recently been studied by dynamic imaging using two-photon microscopy. These studies combined with the early studies of antigen transport have yielded a more complete picture of the orchestration of B cell activation in vivo. Here we summarize the recent advances and focus on the specialized macrophages that are critical to this process and the role of B cells themselves as antigen transporting cells.
|Authors||Phan, T.G, Gray E.E.; Cyster; J.G.:|
|Publisher Name||CURR OPIN IMMUNOL|
|Published Date||2009-06-29 00:00:00|