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The microanatomy of B cell activation.

Abstract

The logistic problem of B cell antigen encounter in the lymph node has recently been studied by dynamic imaging using two-photon microscopy. These studies combined with the early studies of antigen transport have yielded a more complete picture of the orchestration of B cell activation in vivo. Here we summarize the recent advances and focus on the specialized macrophages that are critical to this process and the role of B cells themselves as antigen transporting cells.

Type Journal
ISBN 1879-0372 (Electronic)
Authors Phan, T.G, Gray E.E.; Cyster; J.G.:
Responsible Garvan Author A/Prof Tri Phan
Publisher Name CURRENT OPINION IN IMMUNOLOGY
Published Date 2009-06-29
Published Volume 21
Published Issue 3
Published Pages 258-65
Status Published in-print
URL link to publisher's version http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19481917
OpenAccess link to author's accepted manuscript version https://publications.gimr.garvan.org.au/open-access/10278