The microanatomy of B cell activation.
The logistic problem of B cell antigen encounter in the lymph node has recently been studied by dynamic imaging using two-photon microscopy. These studies combined with the early studies of antigen transport have yielded a more complete picture of the orchestration of B cell activation in vivo. Here we summarize the recent advances and focus on the specialized macrophages that are critical to this process and the role of B cells themselves as antigen transporting cells.
|Authors||Phan, T.G, Gray E.E.; Cyster; J.G.:|
|Responsible Garvan Author|
|Publisher Name||CURRENT OPINION IN IMMUNOLOGY|
|Published Date||2009-06-29 00:00:00|
|URL link to publisher's version||http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19481917|
|OpenAccess link to author's accepted manuscript version||https://publications.gimr.garvan.org.au/open-access/10278|